AC   PRU50000;
DC   Protein;
TR   Metamotif; -; Nter~5,15~PS50076~15,220~PS51287~0,15~PS51341~35,50~PS51206~65,150~Cter
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Names: Large T antigen
 LT
 LT-AG
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ID   LT
DE   RecName: Full=Large T antigen;
DE            Short=LT;
DE            Short=LT-AG;
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CC   -!- FUNCTION: Initiates DNA unwinding and replication via elaborate
CC       interactions with the viral origin of replication.
CC   -!- SUBUNIT: Forms homohexamers in the presence of ATP.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- DOMAIN: The zinc finger region contributes to protein-protein
CC       interactions essential for the assembly of stable T-antigen hexamers at
CC       the origin of replication and hexamers are needed for subsequent
CC       alterations in the structure of origin DNA.
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DR   PROSITE; PS50076; DNAJ_2; 1; trigger=yes
DR   PROSITE; PS51287; T_AG_OBD; 1; trigger=yes
DR   PROSITE; PS51341; ZF_T_AG_D1; 1; trigger=yes
DR   PROSITE; PS51206; SF3_HELICASE_1; 1; trigger=yes
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GO   GO:0005634; C:nucleus
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KW   Early protein
KW   Nucleus
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FT   From: any
FT   CHAIN           from..to
FT                   /note="Large T antigen"
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Size: 580-790;
Related: None;
Example: Q53R41;
Scope:
 Eukaryota
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
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# Revision 1.9 2019/11/22
//