annotation rule: PRU00981

General rule information [?]

Accession PRU00981
Dates 5-JUL-2012 (Created)
26-JUL-2017 (Last updated, Version 5)
Data class Domain
Predictors PROSITE; PS50888; BHLH
Name Myc-type, basic helix-loop-helix (bHLH) domain
Function Fill in

Propagated annotation [?]

Comments [?]

Subcellular location Nucleus.
case not <FTTag:basic>
Caution Contains a degenerate basic motif not likely to bind DNA.
end case

Gene Ontology [?]

GO:0005634; Cellular component: nucleus.

Keywords [?]

case <FTTag:basic>
end case

Features [?]

From: PS50888
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       bHLH #        
REGION     15     to       Helix-loop-helix motif #        
case <Feature:PS50888:1-14=x(0,)-[RK]-x(0,)-[RK]-x(0,)-[RK]-x(0,)-[RK]-x(0,)>
REGION     from     14       Basic motif #   basic      
REGION     from     14       Basic motif #; degenerate        
end case

Additional information [?]

Size range 38-115 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9W6C8 (NDF2_DANRE)
Scope Eukaryota
Viruses; Retroviridae
Comments None


PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to or see: prosite_license.html.

UniProtKB rule member sequences [?]