annotation rule: PRU01103

General rule information [?]

Accession PRU01103
Dates 21-JUL-2015 (Created)
16-DEC-2016 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51767; PEPTIDASE_A1
Name Peptidase family A1 domain
Function Eukaryotic aspartyl proteases (APs) form peptidase family A1 of clan AA. APs use an Asp dyad to hydrolyze peptide bonds.

Propagated annotation [?]


Comments [?]

Similarity Belongs to the peptidase A1 family.

Cross-references [?]

PROSITE PS00141; ASP_PROTEASE; 2;

Gene Ontology [?]

case <FTGroup:1>
GO:0004190; Molecular function: aspartic-type endopeptidase activity.

Keywords [?]

end case

case <FTTag:disulf>
end case


Features [?]

From: PS51767
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Peptidase A1 #        
ACT_SITE     19     19             D   1
ACT_SITE     204     204             D   1
DISULFID     239     274           disulf   C-x*-C  

Additional information [?]

Size range 211-432 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P32951 (CARP1_CANPA)
Scope Eukaryota
Comments None

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]