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ProRule PRU10004


General rule information [?]

Accession PRU10004
Dates 16-OCT-2006 (Created)
14-MAY-2022 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS00068; MDH
Name Malate dehydrogenase active site
Function Undefined
Scope(s) Eukaryota
Bacteria
Example(s) Q5U907 (MDH_ACTSZ);

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + AltName: Full=Malate dehydrogenase;
                 EC=1.1.1.37;

Comments [?]

CATALYTIC ACTIVITY Reaction=(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate; Xref=Rhea:RHEA:21432, ChEBI:CHEBI:15378, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.37;

Features [?]

From: PS00068
Key From To Description Tag Condition FTGroup
ACT_SITE 5 5 /note="Proton relay"
BINDING 6 6 /ligand="substrate"

Additional information [?]

Size range unlimited amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]