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ProRule PRU10116


General rule information [?]

Accession PRU10116
Dates 16-OCT-2006 (Created)
22-NOV-2019 (Last updated, Version 5)
Data class Domain;
Predictors PROSITE; PS01226; HMG_COA_SYNTHASE
Name Hydroxymethylglutaryl-coenzyme A synthase active site
Function Undefined
Scope(s) Eukaryota
Example(s) P23228 (HMCS1_CHICK);

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + AltName: Full=Hydroxymethylglutaryl-CoA synthase;
                 EC=2.3.3.10;

Comments [?]

CATALYTIC ACTIVITY Reaction=acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-hydroxy-3- methylglutaryl-CoA + CoA + H(+); Xref=Rhea:RHEA:10188, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:43074, ChEBI:CHEBI:57286, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.3.10;

Features [?]

From: PS01226
Key From To Description Tag Condition FTGroup
ACT_SITE 10 10

Additional information [?]

Size range unlimited amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



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UniProtKB rule member sequences [?]