PROSITE documentation PDOC00053
Ribosomal protein S11 signature


Ribosomal protein S11 [1] plays an essential role in selecting the correct tRNA in protein biosynthesis. It is located on the large lobe of the small ribosomal subunit. S11 belongs to a family of ribosomal proteins which, on the basis of sequence similarities, groups [2]:

  • Eubacterial S11.
  • Algal and plant chloroplast S11.
  • Cyanelle S11.
  • Archaebacterial S11.
  • Marchantia polymorpha and Prototheca wickerhamii mitochondrial S11.
  • Acanthamoeba castellanii mitochondrial S11.
  • Neurospora crassa S14 (crp-2).
  • Yeast S14 (RP59 or CRY1).
  • Mammalian, Drosophila, Trypanosoma, and plant S14.
  • Caenorhabditis elegans S14 (F37C12.9).

We selected one of the best conserved regions in these proteins as a signature pattern.

Last update:

December 2004 / Pattern and text revised.


Technical section

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_S11, PS00054; Ribosomal protein S11 signature  (PATTERN)


1AuthorsKimura T. Nishikawa M. Fujisawa J.
TitleUncleaved env gp160 of human immunodeficiency virus type 1 is degraded within the Golgi apparatus but not lysosomes in COS-1 cells.
SourceFEBS Lett. 390:15-20(1996).
PubMed ID8706820

2AuthorsOtaka E. Hashimoto T. Mizuta K.
SourceProtein Seq. Data Anal. 5:285-300(1993).

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


View entry in original PROSITE document format
View entry in raw text format (no links)