PROSITE documentation PDOC00055
Ribosomal protein S17 signature


Ribosomal protein S17 is one of the proteins from the small ribosomal subunit. In Escherichia coli, S17 is known to bind specifically to the 5' end of 16S ribosomal RNA and is thought to be involved in the recognition of termination codons. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2,3], groups:

  • Eubacterial S17.
  • Plant chloroplast S17 (nuclear encoded).
  • Red algal chloroplast S17.
  • Cyanelle S17.
  • Archaebacterial S17.
  • Mammalian and plant cytoplasmic S11.
  • Yeast S18a and S18b (RP41; YS12).

As a signature pattern, we selected the best conserved regions located in the C-terminal section of these proteins.

Last update:

November 1997 / Pattern and text revised.


Technical section

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_S17, PS00056; Ribosomal protein S17 signature  (PATTERN)


1AuthorsGantt J.S. Thompson M.D.
TitlePlant cytosolic ribosomal protein S11 and chloroplast ribosomal protein CS17. Their primary structures and evolutionary relationships.
SourceJ. Biol. Chem. 265:2763-2767(1990).
PubMed ID2406240

2AuthorsHerfurth E. Hirano H. Wittmann-Liebold B.
TitleThe amino-acid sequences of the Bacillus stearothermophilus ribosomal proteins S17 and S21 and their comparison to homologous proteins of other ribosomes.
SourceBiol. Chem. Hoppe-Seyler 372:955-961(1991).
PubMed ID1772592

3AuthorsOtaka E. Hashimoto T. Mizuta K.
SourceProtein Seq. Data Anal. 5:285-300(1993).

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