PROSITE documentation PDOC00208Gas vesicles protein GVPc repeated domain signature
Gas vesicles are small, hollow, gas filled protein structures found in several cyanobacterial and archaebacterial microorganisms [1]. They allow the positioning of the bacteria at the favorable depth for growth. Gas vesicles are hollow cylindrical tubes, closed by a hollow, conical cap at each end. Both the conical end caps and central cylinder are made up of 4-5 nm wide ribs that run at right angles to the long axis of the structure. Gas vesicles seem to be constituted of two different protein components: GVPa and GVPc.
GVPc is a minor constituent of gas vesicles and seems to be located on the outer surface. Structurally, cyanobacterial GVPc consists of four or five tandem repeats of a 33 residue sequence flanked by sequences of 18 and 10 residues at the N- and C-termini, respectively.
We derived a signature pattern for the repeated domain. This signature spans positions 11 to 33 of that domain.
Note:This pattern is not designed to detect archaebacterial GVPc [2] which is composed of 8 tandem repeats of a sequence very distantly (if at all) related to that of cyanobacterial GVPc.
Last update:June 1992 / Text revised.
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PROSITE method (with tools and information) covered by this documentation:
| 1 | Authors | Walsby A.E. Hayes P.K. |
| Title | Gas vesicle proteins. | |
| Source | Biochem. J. 264:313-322(1989). | |
| PubMed ID | 2513809 |
| 2 | Authors | Jones J.G. Young D.C. DasSarma S. |
| Title | Structure and organization of the gas vesicle gene cluster on the Halobacterium halobium plasmid pNRC100. | |
| Source | Gene 102:117-122(1991). | |
| PubMed ID | 1864501 |
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