The potato inhibitor I family is one of the numerous families of serine
proteinase inhibitors. Members of this protein family are found in plants;
in the seeds of barley or beans [1,2,3], and in potato or tomato leaves where
they accumulate in response to mechanical damage [4,5]. An inhibitor belonging
to this family is also found in leech . It is interesting to note that,
currently, this is the only proteinase inhibitor family to be found both in
plant and animal kingdoms.
Structurally these inhibitors are small (60 to 90 residues) and in contrast
with other families of protease inhibitors, they lack disulfide bonds. They
have a single inhibitory site. The consensus pattern we developed includes
three out of the four residues conserved in all members of this family and is
located in the N-terminal half.
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see prosite_license.html.