PROSITE documentation PDOC00313
Ribosomal protein S15 signature


Ribosomal protein S15 is one of the proteins from the small ribosomal subunit. In Escherichia coli, this protein binds to 16S ribosomal RNA and functions at early steps in ribosome assembly. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2], groups:

  • Eubacterial S15.
  • Archaebacterial Halobacterium marismortui HmaS15 (HS11).
  • Plant chloroplast S15.
  • Yeast mitochondrial S28.
  • Mammalian S13.
  • Brugia pahangi and Wuchereria bancrofti S13 (S15).
  • Yeast S13 (YS15).

S15 is a protein of 80 to 250 amino-acid residues. As a signature pattern, we selected a conserved region located in the C-terminal part of these proteins.

Expert(s) to contact by email:

Ellis S.R.

Last update:

December 2004 / Pattern and text revised.


Technical section

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_S15, PS00362; Ribosomal protein S15 signature  (PATTERN)


1AuthorsDang H. Ellis S.R.
TitleStructural and functional analyses of a yeast mitochondrial ribosomal protein homologous to ribosomal protein S15 of Escherichia coli.
SourceNucleic Acids Res. 18:6895-6901(1990).
PubMed ID2263452

2AuthorsOtaka E. Hashimoto T. Mizuta K.
SourceProtein Seq. Data Anal. 5:285-300(1993).

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