We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC00408FGGY family of carbohydrate kinases signatures
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PURL: https://purl.expasy.org/prosite/documentation/PDOC00408
Description
It has been shown [1] that four different type of carbohydrate kinases seem to be evolutionary related. These enzymes are:
- L-fuculokinase (EC 2.7.1.51) (gene fucK).
- Gluconokinase (EC 2.7.1.12) (gene gntK).
- Glycerokinase (EC 2.7.1.30) (gene glpK).
- Xylulokinase (EC 2.7.1.17) (gene xylB).
- L-xylulose kinase (EC 2.7.1.53) (gene lyxK).
These enzymes are proteins of from 480 to 520 amino acid residues.
As consensus patterns for this family of kinases we selected two conserved regions, one in the central section, the other in the C-terminal section.
Last update:April 2006 / Pattern revised.
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Technical section
PROSITE methods (with tools and information) covered by this documentation:
Reference
| 1 | Authors | Reizer A. Deutscher J. Saier M.H. Jr. Reizer J. |
| Title | Analysis of the gluconate (gnt) operon of Bacillus subtilis. | |
| Source | Mol. Microbiol. 5:1081-1089(1991). | |
| PubMed ID | 1659648 |
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