PROSITE documentation PDOC00456
Ribosomal protein S14 signature


Ribosomal protein S14 is one of the proteins from the small ribosomal subunit. In Escherichia coli, S14 is known to be required for the assembly of 30S particles and may also be responsible for determining the conformation of 16S rRNA at the A site. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [1,2], groups:

  • Eubacterial S14.
  • Algal and plant chloroplast S14.
  • Cyanelle S14.
  • Archaebacterial Methanococcus vannielii S14.
  • Plant mitochondrial S14.
  • Yeast mitochondrial MRP2.
  • Mammalian S29.
  • Yeast YS29A/B.

S14 is a protein of 53 to 115 amino-acid residues. Our signature pattern is based on the few conserved positions located in the center of these proteins.

Last update:

April 2006 / Pattern revised.


Technical section

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_S14, PS00527; Ribosomal protein S14 signature  (PATTERN)


1AuthorsChan Y.-L. Suzuki K. Olvera J. Wool I.G.
TitleZinc finger-like motifs in rat ribosomal proteins S27 and S29.
SourceNucleic Acids Res. 21:649-655(1993).
PubMed ID8441676

2AuthorsOtaka E. Hashimoto T. Mizuta K.
SourceProtein Seq. Data Anal. 5:285-300(1993).

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


View entry in original PROSITE document format
View entry in raw text format (no links)