|PROSITE documentation PDOC00717|
Trehalase (EC 188.8.131.52) is the enzyme responsible for the degradation of the disaccharide α,α-trehalose yielding two glucose subunits . It is an enzyme found in a wide variety of organisms and whose sequence has been highly conserved throughout evolution.
As signature patterns we selected two of the most highly conserved regions. The first pattern is located in the central section, the second one is in the C-terminal region.Note:
December 2004 / Pattern and text revised.
PROSITE methods (with tools and information) covered by this documentation:
|1||Authors||Kopp M., Mueller H., Holzer H.|
|Title||Molecular analysis of the neutral trehalase gene from Saccharomyces cerevisiae.|
|Source||J. Biol. Chem. 268:4766-4774(1993).|
|2||Authors||Henrissat B., Bairoch A.|
|Title||New families in the classification of glycosyl hydrolases based on amino acid sequence similarities.|
|Source||Biochem. J. 293:781-788(1993).|