We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC00874Uncharacterized protein family UPF0034 signature
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PURL: https://purl.expasy.org/prosite/documentation/PDOC00874
Description
The following uncharacterized proteins have been shown [1] to share regions of similarities:
- Escherichia coli hypothetical protein yhdG and HI0979, the corresponding Haemophilus influenzae protein.
- Escherichia coli hypothetical protein yjbN and HI0634, the corresponding Haemophilus influenzae protein.
- Escherichia coli hypothetical protein yohI and HI0270, the corresponding Haemophilus influenzae protein.
- Bacillus subtilis hypothetical protein yacF.
- Rhodobacter capsulatus protein nifR3 and related proteins in Azospirillum brasilense and Rhizobium leguminosarum.
- Synechocystis strain PCC 6803 hypothetical protein slr0644.
- Synechocystis strain PCC 6803 hypothetical protein sll0926.
- Caenorhabditis elegans hypothetical protein C45G9.2.
- Yeast protein SMM1.
- Yeast hypothetical protein YLR401c.
- Yeast hypothetical protein YLR405w.
- Yeast hypothetical protein YML080w.
Although it has been proposed [2] that Rhodobacter capsulatus nifR3 is a transcriptional regulatory protein, we believe that these proteins constitute a family of enzymes whose active site could include a conserved cysteine which we have used as the central part of a signature pattern.
Last update:April 2006 / Pattern revised.
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Technical section
PROSITE method (with tools and information) covered by this documentation:
References
| 1 | Authors | Bairoch A. Rudd K.E. |
| Source | Unpublished observations (1995). |
| 2 | Authors | Foster-Hartnett D. Cullen P.J. Gabbert K.K. Kranz R.G. |
| Source | Mol. Microbiol. 8:903-914(1993). |
Copyright
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