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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE documentation PDOC00935
Mrp family signature


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PURL: https://purl.expasy.org/prosite/documentation/PDOC00935

Description

The Escherichia coli protein mrp is a 41 Kd ATP-binding protein of unknown function. Homologs are present in other bacteria (for example: Bacillus subtilis ybaL, Hemophilus influenzae HI1277, Synechocystis PCC 6803 slr0067) as well as in eukaryotes (human NBP, yeast NBP35 and YIL003w, Caenorhabditis elegans F10G8.6) and in archaebacteria (Methanococcus jannaschii MJ0283).

We developed a signature pattern for this family based on a conserved region located about 100 residues after the ATP/GTP-binding motif 'A' (P-loop) (see <PDOC00017>).

Last update:

December 2001 / Pattern and text revised.

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Technical section

PROSITE method (with tools and information) covered by this documentation:

MRP, PS01215; Mrp family signature  (PATTERN)


Reference



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