![]() |
|
PROSITE documentation PDOC00937 |
A number of proteins involved in the transport of ammonium ions across a membrane as well as some yet uncharacterized proteins have been shown [1,2] to be evolutionary related. These proteins are:
As expected by their transport function, these proteins are highly hydrophobic and seem to contain from 10 to 12 transmembrane domains. The best conserved region seems to be located in the fifth (or sixth) transmembrane region and is used as a signature pattern.
Note:These proteins belongs to family TC 2.49 in the classification of transporters [3].
Last update:December 2004 / Pattern and text revised.
-------------------------------------------------------------------------------
PROSITE method (with tools and information) covered by this documentation:
1 | Authors | Ninnemann O. Jauniaux J.-C. Frommer W.B. |
Title | Identification of a high affinity NH4+ transporter from plants. | |
Source | EMBO J. 13:3464-3471(1994). | |
PubMed ID | 8062823 |
2 | Authors | Siewe R.M. Weil B. Burkovski A. Eikmanns B.J. Eikmanns M. Kramer R. |
Title | Functional and genetic characterization of the (methyl)ammonium uptake carrier of Corynebacterium glutamicum. | |
Source | J. Biol. Chem. 271:5398-5403(1996). | |
PubMed ID | 8621394 |
3 | Authors | Saier M.H. Jr. |
Source | Adv. Microbiol. Physiol. 40:81-136(1998). |