We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC00958RIO1/ZK632.3/MJ0444 family signature
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PURL: https://purl.expasy.org/prosite/documentation/PDOC00958
Description
The following uncharacterized proteins are evolutionary related [1]:
- Yeast protein RIO1.
- Caenorhabditis elegans hypothetical protein ZK632.3.
- Methanococcus jannaschii hypothetical protein MJ0444.
- Thermoplasma acidophilum hypothetical protein if rpoA2 3'region.
The eukaryotic members of this family are proteins of about 55 to 60 Kd, while the archebacterial ones are half that size. The central part of these proteins is highly conserved. We selected the best conserved region as a signature pattern.
Last update:December 2004 / Pattern and text revised.
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Technical section
PROSITE method (with tools and information) covered by this documentation:
Reference
| 1 | Authors | Bairoch A. |
| Source | Unpublished observations (1997). |
Copyright
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.