The following uncharacterized proteins are evolutionary related :
Yeast protein RIO1.
Caenorhabditis elegans hypothetical protein ZK632.3.
Methanococcus jannaschii hypothetical protein MJ0444.
Thermoplasma acidophilum hypothetical protein if rpoA2 3'region.
The eukaryotic members of this family are proteins of about 55 to 60 Kd, while
the archebacterial ones are half that size. The central part of these proteins
is highly conserved. We selected the best conserved region as a signature
PROSITE method (with tools and information) covered by this documentation:
Unpublished observations (1997).
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