|PROSITE documentation PDOC00993|
Mono(ADP-ribosyl)transferase (EC 126.96.36.199) catalyzes the transfer of the ADP-ribose moiety of nicotinamide adenine dinucleotide (NAD) to an acceptor amino acid in proteins. In vertebrates there is a family of such enzymes that transfer an NAD group to arginine .
At least five distinct forms of this enzyme has been found so far, some are attached to the membrane by a GPI anchor while others seem to be secreted. They are proteins of about 250 to 300 amino acid residues. As a signature pattern, we selected a conserved region in the central section of these enzymes.Last update:
December 2004 / Pattern and text revised.
PROSITE method (with tools and information) covered by this documentation:
|1||Authors||Okazaki I.J. Kim H.-J. Moss J.|
|Title||Cloning and characterization of a novel membrane-associated lymphocyte NAD:arginine ADP-ribosyltransferase.|
|Source||J. Biol. Chem. 271:22052-22057(1996).|