We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC01006Uncharacterized protein family UPF0758 signature
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PURL: https://purl.expasy.org/prosite/documentation/PDOC01006
Description
UPF0758 was previously known as the radC family. The name was assigned according to the radC102 mutant of E. coli which was later demonstrated to be an allele of the transcription-repair-coupling factor recG (see <PDOC51192>) [1,2]. The function of the UPF0758 remains to be determined.
As a signature pattern, we selected a perfectly conserved hexapeptide that contains two histidines.
Last update:October 2009 /Text revised.
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Technical section
PROSITE method (with tools and information) covered by this documentation:
References
| 1 | Authors | Lombardo M.J. Rosenberg S.M. |
| Title | radC102 of Escherichia coli is an allele of recG. | |
| Source | J. Bacteriol. 182:6287-6291(2000). | |
| PubMed ID | 11053371 |
| 2 | Authors | Attaiech L. Granadel C. Claverys J.P. Martin B. |
| Title | RadC, a misleading name? | |
| Source | J. Bacteriol. 190:5729-5732(2008). | |
| PubMed ID | 18556794 | |
| DOI | 10.1128/JB.00425-08 |
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