PROSITE documentation PDOC01006Uncharacterized protein family UPF0758 signature
Description
UPF0758 was previously known as the radC family. The name was assigned according to the radC102 mutant of E. coli which was later demonstrated to be an allele of the transcription-repair-coupling factor recG (see <PDOC51192>) [1,2]. The function of the UPF0758 remains to be determined.
As a signature pattern, we selected a perfectly conserved hexapeptide that contains two histidines.
Last update:October 2009 /Text revised.
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Technical section
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References
| 1 | Authors | Lombardo M.J. Rosenberg S.M. |
| Title | radC102 of Escherichia coli is an allele of recG. | |
| Source | J. Bacteriol. 182:6287-6291(2000). | |
| PubMed ID | 11053371 |
| 2 | Authors | Attaiech L. Granadel C. Claverys J.P. Martin B. |
| Title | RadC, a misleading name? | |
| Source | J. Bacteriol. 190:5729-5732(2008). | |
| PubMed ID | 18556794 | |
| DOI | 10.1128/JB.00425-08 |
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