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PROSITE documentation PDOC01007 |
The following prokaryotic transport proteins are evolutionary related [1]:
These transport proteins belong to a family known as BCCT (for βine / Carnitine / Choline Transporters) which are specific for compounds containing a quaternary nitrogen atom. These proteins contains 12 transmembrane regions and are energized by proton symport. They contains a concerved region with 4 tryptophans in their central region. We use this region as a signature pattern.
Note:These proteins belongs to family TC 2.33 in the classification of transporters [2].
Last update:December 2004 / Pattern and text revised.
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PROSITE method (with tools and information) covered by this documentation:
1 | Authors | Kappes R.M. Kempf B. Bremer E. |
Title | Three transport systems for the osmoprotectant glycine betaine operate in Bacillus subtilis: characterization of OpuD. | |
Source | J. Bacteriol. 178:5071-5079(1996). | |
PubMed ID | 8752321 |
2 | Authors | Saier M.H. Jr. |
Source | Adv. Microbiol. Physiol. 40:81-136(1998). |