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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE documentation PDOC01008
ubiH/COQ6 monooxygenase family signature


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PURL: https://purl.expasy.org/prosite/documentation/PDOC01008

Description

The following proteins are evolutionary related:

  • Escherichia coli ubiH, which is involved in ubiquinone biosynthesis and which catalyzes the convertion of 2-octaprenyl-6-methoxyphenol to 2- octaprenyl-6-methoxy-1,4-benzoquinone.
  • Yeast COQ6, a ubiquinone biosynthesis monooxygenase.
  • Caenorhabditis elegans hypothetical protein K07B1.2.
  • Escherichia coli protein visC.
  • Escherichia coli hypothetical protein yleB.
  • Synechocystis strain PCC 6803 hypothetical protein slr1300.

UbiH and COQ6 are monooxygenases that requires FAD as a cofactor. These are proteins of 42 to 54 Kd that can be picked up by the following pattern.

Last update:

July 1998 / First entry.

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Technical section

PROSITE method (with tools and information) covered by this documentation:

UBIH, PS01304; ubiH/COQ6 monooxygenase family signature  (PATTERN)


Reference



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