We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC01021SsrA-binding protein
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PURL: https://purl.expasy.org/prosite/documentation/PDOC01021
Description
A protein which orignally was called, in Escherichia coli, small protein B (gene smpB) binds specifically to the ssrA RNA (tmRNA) and is required for stable association of ssrA with ribosomes [1]. It is a hydrophilic protein of about 145 to 160 amino-acid residues.
As a signature pattern, we selected a conserved region in the N-terminal section.
Last update:December 2001 / Pattern and text revised.
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Technical section
PROSITE method (with tools and information) covered by this documentation:
Reference
| 1 | Authors | Karzai A.W. Susskind M.M. Sauer R.T. |
| Title | SmpB, a unique RNA-binding protein essential for the peptide-tagging activity of SsrA (tmRNA). | |
| Source | EMBO J. 18:3793-3799(1999). | |
| PubMed ID | 10393194 | |
| DOI | 10.1093/emboj/18.13.3793 |
Copyright
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