PROSITE documentation PDOC01023
Ribosome-binding factor A signature


Ribosome-binding factor A [1] (gene rbfA) is a bacterial protein that associates with free 30S ribosomal subunits. It does not associates with 30S subunits that are part of 70S ribosomes or polysomes. It is essential for efficient processing of 16S rRNA.

Ribosome-binding factor A is a protein of from 13 to 15 Kd which is found in most prokaryotic organisms. A putative chloroplastic form seems to exist in plants [2].

As a signature pattern, we selected the best conserved region which is located in the second half of the protein.

Last update:

December 2004 / Pattern and text revised.


Technical section

PROSITE method (with tools and information) covered by this documentation:

RBFA, PS01319; Ribosome-binding factor A signature  (PATTERN)


1AuthorsBylund G.O. Wipemo L.C. Lundberg L.A. Wikstrom P.M.
TitleRimM and RbfA are essential for efficient processing of 16S rRNA in Escherichia coli.
SourceJ. Bacteriol. 180:73-82(1998).
PubMed ID9422595

2AuthorsBairoch A.
SourceUnpublished observations (1998).

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