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PROSITE documentation PDOC50901 |
The FtsK domain is a hydrophilic domain of about 200 residues, which is found in:
The FtsK domain contains a highly conserved putative ATP-binding P-loop motif (see <PDOC00017>) and is assumed to be cytoplasmic. It can be found in one to three copies and is thought to be involved in DNA translocation by coupling ATP hydrolysis to movement relative to the long axis of DNA [1,2,3].
The profile we developed covers the entire FtsK domain.
Last update:August 2003 / Text revised.
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PROSITE method (with tools and information) covered by this documentation:
1 | Authors | Begg K.J. Dewar S.J. Donachie W.D. |
Title | A new Escherichia coli cell division gene, ftsK. | |
Source | J. Bacteriol. 177:6211-6222(1995). | |
PubMed ID | 7592387 |
2 | Authors | Errington J. Bath J. Wu L.J. |
Title | DNA transport in bacteria. | |
Source | Nat. Rev. Mol. Cell Biol. 2:538-545(2001). | |
PubMed ID | 11433368 | |
DOI | 10.1038/35080005 |
3 | Authors | Pallen M.J. |
Title | The ESAT-6/WXG100 superfamily -- and a new Gram-positive secretion system? | |
Source | Trends Microbiol. 10:209-212(2002). | |
PubMed ID | 11973144 |