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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE documentation PDOC51648
YcgL domain profile


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PURL: https://purl.expasy.org/prosite/documentation/PDOC51648

Description

YcgL represents a conserved class of small proteins widespread in γproteobacteria. This group of protein contains a 85-residue domain of unknown function. The YcgL domain contains two α-helices and four β-strands in the sequential arrangement β1-β2-α1-β3-α2-β4 as a 3-layer (α/β/α) sandwich (see <PDB:2H7A>) [1].

The profile we developed covers the entire YcgL domain.

Last update:

June 2012 / First entry.

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Technical section

PROSITE method (with tools and information) covered by this documentation:

YCGL, PS51648; YcgL domain profile  (MATRIX)


Reference

1AuthorsMinailiuc O.M. Vavelyuk O. Gandhi S. Hung M.-N. Cygler M. Ekiel I.
TitleNMR structure of YcgL, a conserved protein from Escherichia coli representing the DUF709 family, with a novel alpha/beta/alpha sandwich fold.
SourceProteins 66:1004-1007(2007).
PubMed ID17221885
DOI10.1002/prot.21198



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