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PROSITE entry PS00011


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PURL: https://purl.expasy.org/prosite/signature/PS00011

Direct ScanProsite submission
General information about the entry

Entry name [info] GLA_1
Accession [info] PS00011
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-MAY-2005 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00011

Name and characterization of the entry

Description [info] Vitamin K-dependent carboxylation domain.
Pattern [info] 
E-x(2)-[ERK]-E-x-C-x(6)-[EDR]-x(10,11)-[FYA]-[YW].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 120 in 120 different sequences
Number of true positive hits 118 in 118 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 3
Number of 'partial' sequences 6
Precision (true positives / (true positives + false positives)) 98.33 %
Recall (true positives / (true positives + false negatives)) 97.52 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 118 sequences 

FA101_PSETE (Q1L659), FA102_PSETE (Q1L658), FA10_BOVIN  (P00743), 

FA10_CHICK  (P25155), FA10_HUMAN  (P00742), FA10_MOUSE  (O88947), 
FA10_RABIT  (O19045), FA10_RAT(Q63207), FA10_TROCA  (Q4QXT9), 
FA7_BOVIN   (P22457), FA7_HUMAN   (P08709), FA7_MOUSE   (P70375), 
FA7_PANPA   (Q2F9P4), FA7_PANTR   (Q2F9P2), FA7_RABIT   (P98139), 
FA7_RAT (Q8K3U6), FA9_BOVIN   (P00741), FA9_CANLF   (P19540), 
FA9_CHICK   (Q804X6), FA9_FELCA   (Q6SA95), FA9_HUMAN   (P00740), 
FA9_MOUSE   (P16294), FA9_PANTR   (Q95ND7), FA9_PIG (P16293), 
FA9_RAT (P16296), FAXC_OXYMI  (Q58L95), FAXC_OXYSU  (Q58L96), 
FAXC_PSETE  (Q56VR3), FAXD1_DEMVE (A6MFK7), FAXD1_NOTSC (P82807), 
FAXD2_DEMVE (A6MFK8), FAXD2_NOTSC (Q58L94), FAXD_CRYNI  (B5G6G5), 
FAXD_HOPST  (P83370), FAXD_PSEPO  (Q58L93), FAXD_TROCA  (P81428), 
GAS6_HUMAN  (Q14393), GAS6_MOUSE  (Q61592), GAS6_RAT(Q63772), 
MGP_BOVIN   (P07507), MGP_CHICK   (O42413), MGP_CHILA   (Q6QN06), 
MGP_GALGA   (P56620), MGP_HUMAN   (P08493), MGP_MOUSE   (P19788), 
MGP_PIG (Q8MJ39), MGP_PONAB   (Q5RDP6), MGP_RABIT   (P47841), 
MGP_RAT (P08494), OSTC1_DIPSG (P86867), OSTC1_SOLSE (Q1EG28), 
OSTC2_DIPSG (K7NTD0), OSTC2_MOUSE (P86547), OSTC2_SOLSE (P86863), 
OSTCN_ARGRE (Q800Y1), OSTCN_ATEGE (A2D4U1), OSTCN_BISPR (P83489), 
OSTCN_BOVIN (P02820), OSTCN_CAMBA (P86314), OSTCN_CAMDR (P86313), 
OSTCN_CANLF (P81455), OSTCN_CAPHI (P0C225), OSTCN_CHICK (P02822), 
OSTCN_CYPCA (Q7LZI4), OSTCN_DANRE (P83238), OSTCN_DRONO (P15504), 
OSTCN_FELCA (P02821), OSTCN_GORGO (P84349), OSTCN_HORSE (P83005), 
OSTCN_HUMAN (P02818), OSTCN_LAMGU (P86315), OSTCN_LEPMA (P28317), 
OSTCN_MACFA (P02819), OSTCN_MACMU (A2D670), OSTCN_MACNE (A2T6K4), 
OSTCN_MOUSE (P86546), OSTCN_NOTEU (P0C226), OSTCN_PANTR (P84348), 
OSTCN_PIG   (Q8HYY9), OSTCN_PONPY (P84350), OSTCN_RABIT (P39056), 
OSTCN_RAT   (P04640), OSTCN_SPAAU (P40148), OSTCN_XENLA (P40147), 
OSTCN_XENTR (Q6DJ00), OSTCN_XIPGL (P02823), OSTR_MOUSE  (P54615), 
PROC_BOVIN  (P00745), PROC_CANLF  (Q28278), PROC_HUMAN  (P04070), 
PROC_MOUSE  (P33587), PROC_PIG(Q9GLP2), PROC_RABIT  (Q28661), 
PROC_RAT(P31394), PROS_BOVIN  (P07224), PROS_HUMAN  (P07225), 
PROS_MACMU  (Q28520), PROS_MOUSE  (Q08761), PROS_RABIT  (P98118), 
PROS_RAT(P53813), PROZ_BOVIN  (P00744), PROZ_HUMAN  (P22891), 
PROZ_MOUSE  (Q9CQW3), THRB_BOVIN  (P00735), THRB_HUMAN  (P00734), 
THRB_MOUSE  (P19221), THRB_PIG(Q19AZ8), THRB_PONAB  (Q5R537), 
THRB_RAT(P18292), TMG1_BOVIN  (A7Z070), TMG1_HUMAN  (O14668), 
TMG1_PONAB  (Q5RCB6), TMG2_HUMAN  (O14669), TMG2_MOUSE  (Q8R182), 
TMG3_HUMAN  (Q9BZD7), TMG3_MOUSE  (Q6PAQ9), TMG4_HUMAN  (Q9BZD6), 
TMG4_MOUSE  (Q8BGN6)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

MGP_ARGRE   (Q800Y2), OST2A_ONCMY (A0A024QYT3), OST2B_ONCMY (K9J977)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			6 sequences
			


			
FAXD_NOTSN  (P0CY52), MGP_PRIGL   (P83347), OSTCN_CAMHE (P86312), 

			
OSTCN_HALDD (P83473), OSTCN_HOMNE (P84351), THRB_SALSA  (P84122)


			
			» more
			


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			2 sequences
			


			
KAD_BORBU   (O51378), KAD_BORGP   (Q661K1)


				
	

	

		PDB
[Detailed view]		
		
			126 PDB
			


			pdb_00001cfh; pdb_00001cfi; pdb_00001dan; pdb_00001ezq; pdb_00001f0r; pdb_00001f0s; pdb_00001fak; pdb_00001iod; pdb_00001j34; pdb_00001j35; pdb_00001ksn; pdb_00001lpg; 
			
				pdb_00001lpk; pdb_00001lpz; pdb_00001lqd; pdb_00001mgx; pdb_00001nfu; pdb_00001nfw; pdb_00001nfx; pdb_00001nfy; pdb_00001nl0; pdb_00001nl1; pdb_00001nl2; pdb_00001o5d; 
				pdb_00001p0s; pdb_00001pfx; pdb_00001q3m; pdb_00001q8h; pdb_00001vzm; pdb_00001w0y; pdb_00001w2k; pdb_00001whe; pdb_00001whf; pdb_00001wqv; pdb_00001wss; pdb_00001wtg; 
				pdb_00001wun; pdb_00001wv7; pdb_00001x7a; pdb_00001z6j; pdb_00002a2q; pdb_00002aei; pdb_00002aer; pdb_00002b7d; pdb_00002b8o; pdb_00002boh; pdb_00002c4f; pdb_00002cji; 
				pdb_00002ec9; pdb_00002f9b; pdb_00002fir; pdb_00002flb; pdb_00002flr; pdb_00002j2u; pdb_00002j34; pdb_00002j38; pdb_00002j4i; pdb_00002j94; pdb_00002j95; pdb_00002pf1; 
				pdb_00002pf2; pdb_00002spt; pdb_00002uwl; pdb_00002uwo; pdb_00002uwp; pdb_00002vh0; pdb_00002vh6; pdb_00002wyg; pdb_00002wyj; pdb_00002y7x; pdb_00002y7z; pdb_00002y80; 
				pdb_00002y81; pdb_00002y82; pdb_00002zp0; pdb_00002zwl; pdb_00002zzu; pdb_00003ela; pdb_00003th2; pdb_00003th3; pdb_00003th4; pdb_00004bxs; pdb_00004bxw; pdb_00004ibl; 
				pdb_00004mzz; pdb_00004nzq; pdb_00004o03; pdb_00004y6d; pdb_00004y71; pdb_00004y76; pdb_00004y79; pdb_00004y7a; pdb_00004y7b; pdb_00004ylq; pdb_00004zh8; pdb_00004zha; 
				pdb_00004zma; pdb_00005edk; pdb_00005edm; pdb_00006bjr; pdb_00006c2w; pdb_00006m3b; pdb_00006m3c; pdb_00007tpp; pdb_00008eok; pdb_00008i74; pdb_00008i75; pdb_00008i76; 
				pdb_00008rtn; pdb_00008uf7; pdb_00008uud; pdb_00009bur; pdb_00009bux; pdb_00009bvk; pdb_00009bvl; pdb_00009bvm; pdb_00009bvp; pdb_00009bvq; pdb_00009bvr; pdb_00009cli; 
				pdb_00009cln; pdb_00009cls; pdb_00009cm2; pdb_00009cm9; pdb_00009cmo; pdb_00009cth
			
			

			» more