PROSITE logo

PROSITE entry PS00011


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00011
Entry name [info] GLA_1
Accession [info] PS00011
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-MAY-2005 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00011

Name and characterization of the entry

Description [info] Vitamin K-dependent carboxylation domain.
Pattern [info] 
E-x(2)-[ERK]-E-x-C-x(6)-[EDR]-x(10,11)-[FYA]-[YW].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 120 in 120 different sequences
Number of true positive hits 118 in 118 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 3
Number of 'partial' sequences 6
Precision (true positives / (true positives + false positives)) 98.33 %
Recall (true positives / (true positives + false negatives)) 97.52 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 118 sequences 

FA101_PSETE (Q1L659), FA102_PSETE (Q1L658), FA10_BOVIN  (P00743), 

FA10_CHICK  (P25155), FA10_HUMAN  (P00742), FA10_MOUSE  (O88947), 
FA10_RABIT  (O19045), FA10_RAT(Q63207), FA10_TROCA  (Q4QXT9), 
FA7_BOVIN   (P22457), FA7_HUMAN   (P08709), FA7_MOUSE   (P70375), 
FA7_PANPA   (Q2F9P4), FA7_PANTR   (Q2F9P2), FA7_RABIT   (P98139), 
FA7_RAT (Q8K3U6), FA9_BOVIN   (P00741), FA9_CANLF   (P19540), 
FA9_CHICK   (Q804X6), FA9_FELCA   (Q6SA95), FA9_HUMAN   (P00740), 
FA9_MOUSE   (P16294), FA9_PANTR   (Q95ND7), FA9_PIG (P16293), 
FA9_RAT (P16296), FAXC_OXYMI  (Q58L95), FAXC_OXYSU  (Q58L96), 
FAXC_PSETE  (Q56VR3), FAXD1_DEMVE (A6MFK7), FAXD1_NOTSC (P82807), 
FAXD2_DEMVE (A6MFK8), FAXD2_NOTSC (Q58L94), FAXD_CRYNI  (B5G6G5), 
FAXD_HOPST  (P83370), FAXD_PSEPO  (Q58L93), FAXD_TROCA  (P81428), 
GAS6_HUMAN  (Q14393), GAS6_MOUSE  (Q61592), GAS6_RAT(Q63772), 
MGP_BOVIN   (P07507), MGP_CHICK   (O42413), MGP_CHILA   (Q6QN06), 
MGP_GALGA   (P56620), MGP_HUMAN   (P08493), MGP_MOUSE   (P19788), 
MGP_PIG (Q8MJ39), MGP_PONAB   (Q5RDP6), MGP_RABIT   (P47841), 
MGP_RAT (P08494), OSTC1_DIPSG (P86867), OSTC1_SOLSE (Q1EG28), 
OSTC2_DIPSG (K7NTD0), OSTC2_MOUSE (P86547), OSTC2_SOLSE (P86863), 
OSTCN_ARGRE (Q800Y1), OSTCN_ATEGE (A2D4U1), OSTCN_BISPR (P83489), 
OSTCN_BOVIN (P02820), OSTCN_CAMBA (P86314), OSTCN_CAMDR (P86313), 
OSTCN_CANLF (P81455), OSTCN_CAPHI (P0C225), OSTCN_CHICK (P02822), 
OSTCN_CYPCA (Q7LZI4), OSTCN_DANRE (P83238), OSTCN_DRONO (P15504), 
OSTCN_FELCA (P02821), OSTCN_GORGO (P84349), OSTCN_HORSE (P83005), 
OSTCN_HUMAN (P02818), OSTCN_LAMGU (P86315), OSTCN_LEPMA (P28317), 
OSTCN_MACFA (P02819), OSTCN_MACMU (A2D670), OSTCN_MACNE (A2T6K4), 
OSTCN_MOUSE (P86546), OSTCN_NOTEU (P0C226), OSTCN_PANTR (P84348), 
OSTCN_PIG   (Q8HYY9), OSTCN_PONPY (P84350), OSTCN_RABIT (P39056), 
OSTCN_RAT   (P04640), OSTCN_SPAAU (P40148), OSTCN_XENLA (P40147), 
OSTCN_XENTR (Q6DJ00), OSTCN_XIPGL (P02823), OSTR_MOUSE  (P54615), 
PROC_BOVIN  (P00745), PROC_CANLF  (Q28278), PROC_HUMAN  (P04070), 
PROC_MOUSE  (P33587), PROC_PIG(Q9GLP2), PROC_RABIT  (Q28661), 
PROC_RAT(P31394), PROS_BOVIN  (P07224), PROS_HUMAN  (P07225), 
PROS_MACMU  (Q28520), PROS_MOUSE  (Q08761), PROS_RABIT  (P98118), 
PROS_RAT(P53813), PROZ_BOVIN  (P00744), PROZ_HUMAN  (P22891), 
PROZ_MOUSE  (Q9CQW3), THRB_BOVIN  (P00735), THRB_HUMAN  (P00734), 
THRB_MOUSE  (P19221), THRB_PIG(Q19AZ8), THRB_PONAB  (Q5R537), 
THRB_RAT(P18292), TMG1_BOVIN  (A7Z070), TMG1_HUMAN  (O14668), 
TMG1_PONAB  (Q5RCB6), TMG2_HUMAN  (O14669), TMG2_MOUSE  (Q8R182), 
TMG3_HUMAN  (Q9BZD7), TMG3_MOUSE  (Q6PAQ9), TMG4_HUMAN  (Q9BZD6), 
TMG4_MOUSE  (Q8BGN6)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

MGP_ARGRE   (Q800Y2), OST2A_ONCMY (A0A024QYT3), OST2B_ONCMY (K9J977)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			6 sequences
			


			
FAXD_NOTSN  (P0CY52), MGP_PRIGL   (P83347), OSTCN_CAMHE (P86312), 

			
OSTCN_HALDD (P83473), OSTCN_HOMNE (P84351), THRB_SALSA  (P84122)


			
			» more
			


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			2 sequences
			


			
KAD_BORBU   (O51378), KAD_BORGP   (Q661K1)


				
	

	

		PDB
[Detailed view]		
		
			117 PDB
			


			1CFH; 1CFI; 1DAN; 1EZQ; 1F0R; 1F0S; 1FAK; 1IOD; 1J34; 1J35; 1KSN; 1LPG; 
			
				1LPK; 1LPZ; 1LQD; 1MGX; 1NFU; 1NFW; 1NFX; 1NFY; 1NL0; 1NL1; 1NL2; 1O5D; 
				1P0S; 1PFX; 1Q3M; 1Q8H; 1VZM; 1W0Y; 1W2K; 1WHE; 1WHF; 1WQV; 1WSS; 1WTG; 
				1WUN; 1WV7; 1X7A; 1Z6J; 2A2Q; 2AEI; 2AER; 2B7D; 2B8O; 2BOH; 2C4F; 2CJI; 
				2EC9; 2F9B; 2FIR; 2FLB; 2FLR; 2J2U; 2J34; 2J38; 2J4I; 2J94; 2J95; 2PF1; 
				2PF2; 2SPT; 2UWL; 2UWO; 2UWP; 2VH0; 2VH6; 2WYG; 2WYJ; 2Y7X; 2Y7Z; 2Y80; 
				2Y81; 2Y82; 2ZP0; 2ZWL; 2ZZU; 3ELA; 3TH2; 3TH3; 3TH4; 4BXS; 4BXW; 4IBL; 
				4MZZ; 4NZQ; 4O03; 4Y6D; 4Y71; 4Y76; 4Y79; 4Y7A; 4Y7B; 4YLQ; 4ZH8; 4ZHA; 
				4ZMA; 5EDK; 5EDM; 6BJR; 6C2W; 6M3B; 6M3C; 7TPP; 8EOK; 8I74; 8I75; 8I76; 
				8UF7; 8UUD; 9CLI; 9CLN; 9CLS; 9CM2; 9CM9; 9CMO; 9CTH
			
			

			» more