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PROSITE entry PS00020


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General information about the entry

Entry name [info] ACTININ_2
Accession [info] PS00020
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00019

Name and characterization of the entry

Description [info] Actinin-type actin-binding domain signature 2.
Pattern [info]
[LIVM]-x-[SGNL]-[LIVMN]-[DAGHENRS]-[SAGPNVT]-x-[DNEAG]-[LIVM]-x-[DEAGQ]-
x(4)-[LIVM]-x-[LM]-[SAG]-[LIVM]-[LIVMT]-[WS]-x(0,1)-[LIVM](2).

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 105 in 89 different sequences
Number of true positive hits 105 in 89 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.06 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
89 sequences

ACTN1_BOVIN (Q3B7N2), ACTN1_CHICK (P05094), ACTN1_HUMAN (P12814), 
ACTN1_MACFA (Q2PFV7), ACTN1_MOUSE (Q7TPR4), ACTN1_RAT   (Q9Z1P2), 
ACTN2_BOVIN (Q3ZC55), ACTN2_CHICK (P20111), ACTN2_HUMAN (P35609), 
ACTN2_MOUSE (Q9JI91), ACTN3_BOVIN (Q0III9), ACTN3_HUMAN (Q08043), 
ACTN3_MOUSE (O88990), ACTN4_BOVIN (A5D7D1), ACTN4_CHICK (Q90734), 
ACTN4_HUMAN (O43707), ACTN4_MOUSE (P57780), ACTN4_PONAB (Q5RCS6), 
ACTN4_RAT   (Q9QXQ0), ACTNA_DICDI (P05095), ACTNB_DICDI (O76329), 
ACTN_ANOGA  (Q7PKQ5), ACTN_DERFA  (L7UZ85), ACTN_DROME  (P18091), 
AIN1_SCHPO  (O13728), ANC1_CAEEL  (Q9N4M4), CLMN_HUMAN  (Q96JQ2), 
CLMN_MOUSE  (Q8C5W0), DMDA_DROME  (Q9VDW6), DMD_CANLF   (O97592), 
DMD_CHICK   (P11533), DMD_HUMAN   (P11532), DMD_MOUSE   (P11531), 
DMD_PIG (Q5GN48), DMD_RAT (P11530), DYST_HUMAN  (Q03001), 
DYST_MOUSE  (Q91ZU6), FIMB1_ARATH (Q7G188), FIMB2_ARATH (O50064), 
FIMB3_ARATH (Q9FJ70), FIMB5_ARATH (Q9FKI0), FIMB_DICDI  (P54680), 
FIMB_SCHPO  (O59945), FIMB_YEAST  (P32599), FLNA_DROME  (Q9VEN1), 
FLNA_HUMAN  (P21333), FLNA_MOUSE  (Q8BTM8), FLNB_HUMAN  (O75369), 
FLNB_MOUSE  (Q80X90), FLNC_HUMAN  (Q14315), FLNC_MOUSE  (Q8VHX6), 
FLNC_RAT(D3ZHA0), GELA_DICDI  (P13466), MACF1_HUMAN (Q9UPN3), 
MACF1_MOUSE (Q9QXZ0), MACF1_RAT   (D3ZHV2), MS300_DROME (M9MRD1), 
PLEC_CRIGR  (Q9JI55), PLEC_HUMAN  (Q15149), PLEC_MOUSE  (Q9QXS1), 
PLEC_RAT(P30427), PLSI_BOVIN  (A6H742), PLSI_CHICK  (P19179), 
PLSI_HUMAN  (Q14651), PLSI_MOUSE  (Q3V0K9), PLSL_DANRE  (Q6P698), 
PLSL_HUMAN  (P13796), PLSL_MOUSE  (Q61233), PLST_BOVIN  (A7E3Q8), 
PLST_CRIGR  (O88818), PLST_DANRE  (Q6DG81), PLST_HUMAN  (P13797), 
PLST_MOUSE  (Q99K51), PLST_RAT(Q63598), SPTB1_HUMAN (P11277), 
SPTB1_MOUSE (P15508), SPTB2_HUMAN (Q01082), SPTB2_MOUSE (Q62261), 
SPTCB_DROME (Q00963), SPTN2_HUMAN (O15020), SPTN2_RAT   (Q9QWN8), 
SPTN4_HUMAN (Q9H254), SPTN5_HUMAN (Q9NRC6), SYNE1_HUMAN (Q8NF91), 
SYNE1_MOUSE (Q6ZWR6), SYNE2_HUMAN (Q8WXH0), SYNE2_MOUSE (Q6ZWQ0), 
UTRN_HUMAN  (P46939), UTRN_RAT(G3V7L1)
» more

UniProtKB/Swiss-Prot
False negative sequences
1 sequence

DMD_CAEEL   (Q9TW65)

		
PDB
[Detailed view]
46 PDB

1AOA; 1DXX; 1MB8; 1PXY; 1QAG; 1RT8; 1SH5; 1SH6; 1SJJ; 1TJT; 1WKU; 2EYI; 2EYN; 2R0O; 2WA5; 2WA6; 2WA7; 2WFN; 3F7P; 3FER; 3HOC; 3HOP; 3HOR; 3LUE; 4B7L; 4D1E; 4Q57; 4Q58; 4Q59; 4Z6G; 5A36; 5A37; 5A38; 5A4B; 5BVR; 6ANU; 6D8C; 6M5G; 6O31; 6OA6; 6SWT; 6VEC; 7R94; 7SX8; 7SX9; 7SXA
» more