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PROSITE entry PS00021


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General information about the entry

Entry name [info] KRINGLE_1
Accession [info] PS00021
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-SEP-2002 DATA UPDATE;
03-MAY-2023 INFO UPDATE.
PROSITE Doc. [info] PDOC00020

Name and characterization of the entry

Description [info] Kringle domain signature.
Pattern [info] 
[FY]-C-[RH]-[NS]-x(7,8)-[WY]-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2023_02 which contains 569'516 sequence entries.


Total number of hits 198 in 99 different sequences
Number of true positive hits 193 in 94 different sequences
Number of 'unknown' hits 0
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 2
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 97.47 %
Recall (true positives / (true positives + false negatives)) 98.97 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 16
Site [info] disulfide at position 2
Site [info] disulfide at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 94 sequences 

APOA_HUMAN  (P08519    ), APOA_MACMU  (P14417    ), CAM1_CAEEL  (G5EGK5    ), 

FA12_CAVPO  (Q04962    ), FA12_HUMAN  (P00748    ), FA12_MOUSE  (Q80YC5    ), 
FA12_PIG    (O97507    ), FA12_RAT    (D3ZTE0    ), HABP2_BOVIN (Q5E9Z2    ), 
HABP2_HUMAN (Q14520    ), HABP2_MOUSE (Q8K0D2    ), HABP2_RAT   (Q6L711    ), 
HGFA_CANLF  (Q6QNF4    ), HGFA_HUMAN  (Q04756    ), HGFA_MOUSE  (Q9R098    ), 
HGFL_BOVIN  (Q24K22    ), HGFL_HUMAN  (P26927    ), HGFL_MOUSE  (P26928    ), 
HGF_BOVIN   (Q76BS1    ), HGF_CANLF   (Q867B7    ), HGF_FELCA   (Q9BH09    ), 
HGF_HUMAN   (P14210    ), HGF_MOUSE   (Q08048    ), HGF_RAT     (P17945    ), 
KREM1_HUMAN (Q96MU8    ), KREM1_MOUSE (Q99N43    ), KREM1_RAT   (Q924S4    ), 
KREM1_XENLA (Q90Y90    ), KREM2_HUMAN (Q8NCW0    ), KREM2_MOUSE (Q8K1S7    ), 
LPAL2_HUMAN (Q16609    ), MST1L_HUMAN (Q2TV78    ), MUSK_CHICK  (Q8AXY6    ), 
NETR_GORGO  (Q5G270    ), NETR_HUMAN  (P56730    ), NETR_MACMU  (Q5G267    ), 
NETR_MOUSE  (O08762    ), NETR_NOMLE  (Q5G268    ), NETR_PANTR  (Q5G271    ), 
NETR_PONPY  (Q5G269    ), NETR_RAT    (G3V801    ), NETR_SAGLB  (Q5G265    ), 
NETR_TRAPH  (Q5G266    ), P3IP1_BOVIN (Q1RMT9    ), P3IP1_DANRE (Q7SXB3    ), 
P3IP1_HUMAN (Q96FE7    ), P3IP1_MOUSE (Q7TMJ8    ), P3IP1_PONAB (Q5RCS3    ), 
P3IP1_RAT   (Q56A20    ), PLMN_BOVIN  (P06868    ), PLMN_CANLF  (P80009    ), 
PLMN_CAPHI  (Q7M323    ), PLMN_ERIEU  (Q29485    ), PLMN_HORSE  (P80010    ), 
PLMN_HUMAN  (P00747    ), PLMN_MACMU  (P12545    ), PLMN_MOUSE  (P20918    ), 
PLMN_NOTEU  (O18783    ), PLMN_PETMA  (P33574    ), PLMN_PIG    (P06867    ), 
PLMN_PONAB  (Q5R8X6    ), PLMN_RAT    (Q01177    ), PLMN_SHEEP  (P81286    ), 
ROR1_DROME  (Q24488    ), ROR1_HUMAN  (Q01973    ), ROR1_MOUSE  (Q9Z139    ), 
ROR2_DROME  (Q9V6K3    ), ROR2_HUMAN  (Q01974    ), ROR2_MOUSE  (Q9Z138    ), 
THRB_BOVIN  (P00735    ), THRB_HUMAN  (P00734    ), THRB_MOUSE  (P19221    ), 
THRB_PIG    (Q19AZ8    ), THRB_PONAB  (Q5R537    ), THRB_RAT    (P18292    ), 
TPA_BOVIN   (Q28198    ), TPA_HUMAN   (P00750    ), TPA_MOUSE   (P11214    ), 
TPA_PIG     (Q8SQ23    ), TPA_PONAB   (Q5R8J0    ), TPA_RAT     (P19637    ), 
UROK_BOVIN  (Q05589    ), UROK_CHICK  (P15120    ), UROK_HUMAN  (P00749    ), 
UROK_MOUSE  (P06869    ), UROK_PAPCY  (P16227    ), UROK_PIG    (P04185    ), 
UROK_PONAB  (Q5RF29    ), UROK_RABIT  (Q8MHY7    ), UROK_RAT    (P29598    ), 
URT1_DESRO  (P98119    ), URT2_DESRO  (P15638    ), URTB_DESRO  (P98121    ), 
URTG_DESRO  (P49150    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 2 sequences 

FA12_BOVIN  (P98140    ), SVH1_CAEEL  (Q17800    )


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			1 sequence
			


			
THRB_SALSA  (P84122    )


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			5 sequences
			


			
CO1EA_CONGR (J7GY56    ), M7J_CONCN   (P0DKQ6    ), O1641_CONMI (Q3YEG4    ), 

			
O1VA_CONGR  (A0A2I4QAG8), PWAP_HALLA  (P84811    )


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			117 PDB
			


			1A0H; 1B2I; 1BHT; 1CEA; 1CEB; 1GMN; 1GMO; 1GP9; 1HPJ; 1HPK; 1I5K; 1I71; 
			
				1JFN; 1KDU; 1KI0; 1KIV; 1KRN; 1NK1; 1NL1; 1NL2; 1PK2; 1PK4; 1PKR; 1PMK; 
				1PML; 1TPK; 1URK; 2DOH; 2DOI; 2FD6; 2FEB; 2HPP; 2HPQ; 2I9A; 2I9B; 2K4R; 
				2K51; 2KNF; 2L0S; 2PF1; 2PF2; 2PK4; 2QJ2; 2QJ4; 2SPT; 3BT1; 3BT2; 3E6P; 
				3HN4; 3K65; 3KIV; 3LAQ; 3MKP; 3NXP; 3SP8; 3U73; 4A5T; 4BV5; 4BV7; 4BVC; 
				4BVD; 4BVV; 4BVW; 4CIK; 4D3C; 4DUR; 4DUU; 4HZH; 4IUA; 4K24; 4KIV; 4NZQ; 
				4O03; 5COE; 5CP9; 5CS1; 5CS3; 5CS5; 5CS9; 5CSQ; 5CT1; 5CT2; 5CT3; 5EDK; 
				5EDM; 5FWS; 5FWT; 5FWU; 5FWV; 5FWW; 5HPG; 5Z55; 6BA5; 6BAN; 6BJR; 6C2W; 
				6OG4; 6OQJ; 6OQK; 6OSH; 6OSN; 6OSV; 6RX7; 6UZ4; 6UZ5; 7BZT; 7BZU; 7ME4; 
				7MO7; 7MO8; 7MO9; 7MOA; 7MOB; 7OCL; 7OCM; 7TNG; 7TPP
			
			

			» more