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PROSITE entry PS00024


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General information about the entry

Entry name [info] HEMOPEXIN
Accession [info] PS00024
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00023

Name and characterization of the entry

Description [info] Hemopexin domain signature.
Pattern [info] 
[LIFAT]-{IL}-x(2)-W-x(2,3)-[PE]-x-{VF}-[LIVMFY]-[DENQS]-[STA]-[AV]-
[LIVMFY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 132 in 125 different sequences
Number of true positive hits 82 in 75 different sequences
Number of 'unknown' hits 0
Number of false positive hits 50 in 50 different sequences
Number of false negative sequences 23
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 62.12 %
Recall (true positives / (true positives + false negatives)) 78.10 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 75 sequences 

HEMO_BOVIN  (Q3SZV7), HEMO_HUMAN  (P02790), HEMO_MOUSE  (Q91X72), 

HEMO_PIG(P50828), HEMO_PONAB  (Q5R543), HEMO_RABIT  (P20058), 
HEMO_RAT(P20059), HE_HEMPU(P91953), MMP10_HUMAN (P09238), 
MMP10_MOUSE (O55123), MMP10_RAT   (P07152), MMP11_HUMAN (P24347), 
MMP11_MOUSE (Q02853), MMP11_RAT   (Q499S5), MMP11_XENLA (Q11005), 
MMP12_HUMAN (P39900), MMP12_MOUSE (P34960), MMP12_RABIT (P79227), 
MMP12_RAT   (Q63341), MMP13_HORSE (O18927), MMP13_HUMAN (P45452), 
MMP13_MOUSE (P33435), MMP13_RABIT (O62806), MMP13_RAT   (P23097), 
MMP13_XENLA (Q10835), MMP14_BOVIN (Q9GLE4), MMP14_HUMAN (P50281), 
MMP14_MOUSE (P53690), MMP14_PIG   (Q9XT90), MMP14_PONAB (Q5RES1), 
MMP14_RABIT (Q95220), MMP14_RAT   (Q10739), MMP15_HUMAN (P51511), 
MMP15_MOUSE (O54732), MMP16_HUMAN (P51512), MMP16_MOUSE (Q9WTR0), 
MMP16_RAT   (O35548), MMP19_MOUSE (Q9JHI0), MMP1A_MOUSE (Q9EPL5), 
MMP1B_MOUSE (Q9EPL6), MMP1_BOVIN  (P28053), MMP1_HORSE  (Q9XSZ5), 
MMP1_HUMAN  (P03956), MMP1_PIG(P21692), MMP1_RABIT  (P13943), 
MMP24_HUMAN (Q9Y5R2), MMP24_MOUSE (Q9R0S2), MMP24_RAT   (Q99PW6), 
MMP27_HUMAN (Q9H306), MMP27_TUPBE (Q9GKE1), MMP2_BOVIN  (Q9GLE5), 
MMP2_CHICK  (Q90611), MMP2_HUMAN  (P08253), MMP2_MOUSE  (P33434), 
MMP2_RABIT  (P50757), MMP2_RAT(P33436), MMP3_CANLF  (Q6Y4Q5), 
MMP3_HORSE  (Q28397), MMP3_HUMAN  (P08254), MMP3_MOUSE  (P28862), 
MMP3_RABIT  (P28863), MMP3_RAT(P03957), MMP8_HUMAN  (P22894), 
MMP8_MOUSE  (O70138), MMP8_RAT(O88766), MMP9_HUMAN  (P14780), 
MMP9_MOUSE  (P41245), MMP9_RABIT  (P41246), MMP9_RAT(P50282), 
PRG4_HUMAN  (Q92954), PRG4_MOUSE  (Q9JM99), VTNC_HUMAN  (P04004), 
VTNC_MOUSE  (P29788), VTNC_PIG(P48819), VTNC_RABIT  (P22458)
» more

UniProtKB/Swiss-Prot
False negative sequences		 23 sequences 

D2MP_DROME  (Q8MPP3), HE_PARLI(P22757), MMP13_BOVIN (O77656), 

MMP17_HUMAN (Q9ULZ9), MMP17_MOUSE (Q9R0S3), MMP18_XENLA (O13065), 
MMP19_HUMAN (Q99542), MMP1_AQUCT  (Q11133), MMP20_BOVIN (O18767), 
MMP20_HUMAN (O60882), MMP20_MOUSE (P57748), MMP20_PIG   (P79287), 
MMP21_CYNPY (Q90YC2), MMP21_HUMAN (Q8N119), MMP21_MOUSE (Q8K3F2), 
MMP21_XENLA (O93470), MMP25_HUMAN (Q9NPA2), MMP25_MOUSE (Q3U435), 
MMP28_HUMAN (Q9H239), MMP9_BOVIN  (P52176), MMP9_CANLF  (O18733), 
MMPA_CAEEL  (G5EGM1), MMPC_CAEEL  (G5EBU3)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

HEMO_CHICK  (P20057)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			50 sequences
			


			
ASTE_PARXL  (Q141D1), BPHA4_RHOJR (Q0S032), CPLN1_MOUSE (Q8CE72), 

			
DPP6_PANTR  (Q5IS50), GC_PSHV1(Q6UDI7), HISX_PROMM  (Q7V5N9), 
KATG_MYCGI  (A4TA35), LGRC_BREPA  (Q70LM5), LTD_ORYSI   (A2YLX7), 
LTD_ORYSJ   (A3BKF2), MPPE1_AILME (D2I2M6), MPPE1_CHICK (Q5ZK82), 
MPPE1_CRIGR (C7G3A0), MPPE1_HUMAN (Q53F39), MPPE1_MACFA (Q9GMS6), 
MPPE1_MOUSE (Q80XL7), MPPE1_PONAB (Q5RET5), MPPE1_RAT   (B1WC86), 
MPPE1_XENLA (Q0IHA5), MSLN_HUMAN  (Q13421), NIFJ_ECOLI  (P52647), 
OPGG2_SHEON (Q8EDL2), PMA6E_HUMAN (A0A0J9YXQ4), PORCN_CAEBR (A8WZ09), 
STEA4_HUMAN (Q687X5), STEA4_MOUSE (Q923B6), SYE1_RHIWR  (A5V932), 
SYT_HAEDU   (Q7VKR9), TFE_METTP   (A0B9P3), TMCA_CITK8  (A8ADB3), 
TRAK1_HUMAN (Q9UPV9), TRAK1_MOUSE (Q6PD31), TYSY_HALVO  (Q9UWQ5), 
UBID_BURL3  (Q39IR6), UBID_BURMA  (Q62HU9), UBID_BURO1  (Q1BYC0), 
UBID_BURP1  (Q3JPM4), UBID_BURPS  (Q63RP1), UBID_BURTA  (Q2SYC8), 
UBID_METCA  (Q602K0), UBID_NITEU  (Q82TP1), UBID_THIDA  (Q3SMI8), 
URE1_ACIAD  (Q6FD83), URE1_CORGL  (Q79VJ3), UTP20_SCHPO (O60055), 
Y022_ALKMQ  (A6TJ97), Y1488_MYCTO (P9WPR8), Y1488_MYCTU (P9WPR9), 
Y1524_MYCBO (P63694), Y3298_MAGMM (A0LCU4)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			24 PDB
			


			1CK7; 1FBL; 1GEN; 1GXD; 1HXN; 1ITV; 1PEX; 1QHU; 1QJS; 1RTG; 1SU3; 2CLT; 
			
				2JXY; 2MQS; 3BA0; 3C7X; 4AUO; 4FU4; 4FVL; 4G0D; 6CLZ; 6CM1; 6O5E; 7RJ9
			
			

			» more