PROSITE entry PS00025

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PURL: https://purl.expasy.org/prosite/signature/PS00025

Direct ScanProsite submission

General information about the entry

Entry name [info]	P_TREFOIL_1
Accession [info]	PS00025
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00024

Name and characterization of the entry

Description [info]	P-type 'Trefoil' domain signature.
Pattern [info]	[KRH]-x(2)-C-x-[FYPSTV]-x(3,4)-[ST]-x(3)-C-x(4)-C-C-[FYWH].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2026_02 which contains 575'503 sequence entries.

Total number of hits	61 in 45 different sequences
Number of true positive hits	61 in 45 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	8
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	88.41 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	6
Site [info]	disulfide at position 3
Site [info]	disulfide at position 9
Site [info]	disulfide at position 11
Site [info]	disulfide at position 12
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

45 sequences

LYAG_BOVIN  (Q9MYM4), LYAG_HUMAN  (P10253), LYAG_MOUSE  (P70699),

LYAG_PONAB  (Q5R7A9), LYAG_RAT(Q6P7A9), MGA_HUMAN   (O43451), 
MLRP1_ACRMI (B3EWZ5), MLRP2_ACRMI (B3EWZ6), MUA1_XENLA  (P10667), 
MUC1_XENLA  (Q05049), SUIS_HUMAN  (P14410), SUIS_MOUSE  (B5THE3), 
SUIS_PIG(P56729), SUIS_RABIT  (P07768), SUIS_RAT(P23739), 
SUIS_SUNMU  (O62653), TFF1_CANLF  (Q863T4), TFF1_HUMAN  (P04155), 
TFF1_MOUSE  (Q08423), TFF1_RAT(Q63467), TFF2_CANLF  (Q863J2), 
TFF2_HUMAN  (Q03403), TFF2_MOUSE  (Q03404), TFF2_PIG(P01359), 
TFF2_RAT(Q09030), TFF3_BOVIN  (A8YXX7), TFF3_CANLF  (Q863B4), 
TFF3_FELCA  (B4X8D9), TFF3_HUMAN  (Q07654), TFF3_MOUSE  (Q62395), 
TFF3_PIG(Q29183), TFF3_RAT(Q03191), XP1_XENLA   (Q00222), 
XP2_XENLA   (P17437), XP4_XENLA   (Q00223), ZP1_HUMAN   (P60852), 
ZP1_MOUSE   (Q62005), ZP1_RABIT   (I6M4H4), ZP1_RAT (O54766), 
ZP4_BOVIN   (Q9BH11), ZP4_FELCA   (P48834), ZP4_HUMAN   (Q12836), 
ZP4_PIG (Q07287), ZP4_RABIT   (Q00193), ZP4_RAT (Q8CH34)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

8 sequences

FMR1N_HUMAN (Q8N0W7), FMR1N_MOUSE (Q80ZA7), FYV1_DICDI  (B0G126),

MGAL_HUMAN  (Q2M2H8), TM190_BOVIN (E1BJD3), TM190_CANLF (E2R0A5), 
TM190_HUMAN (Q8WZ59), TM190_MOUSE (Q9D2E9)

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PDB
[Detailed view]

41 PDB

pdb_00001e9t; pdb_00001hi7; pdb_00001pcp; pdb_00001pe3; pdb_00001pos; pdb_00001ps2; pdb_00001psp; pdb_00002psp; pdb_00002qly; pdb_00002qmj; pdb_00003ctt; pdb_00003l4t; pdb_00003l4u; pdb_00003l4v; pdb_00003l4w; pdb_00003l4x; pdb_00003l4y; pdb_00003l4z; pdb_00003lpo; pdb_00003lpp; pdb_00005kzw; pdb_00005kzx; pdb_00005nn3; pdb_00005nn4; pdb_00005nn5; pdb_00005nn6; pdb_00005nn8; pdb_00006v1c; pdb_00006v1d; pdb_00007p2z; pdb_00007p32; pdb_00008cb1; pdb_00008cb6; pdb_00009gsv; pdb_00009gsw; pdb_00009gtc; pdb_00009gtd; pdb_00009gtl; pdb_00009gtn; pdb_00009gtt; pdb_00009gtw
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