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PROSITE entry PS00060


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00060
Entry name [info] ADH_IRON_2
Accession [info] PS00060
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00059

Name and characterization of the entry

Description [info] Iron-containing alcohol dehydrogenases signature 2.
Pattern [info] 
[GSW]-x-[LIVTSACD]-[GH]-x(2)-[GSAE]-[GSHYQ]-x-[LIVTP]-[GAST]-[GAS]-x(3)-
[LIVMT]-x-[HNS]-[GA]-x-[GTAC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 38 in 38 different sequences
Number of true positive hits 35 in 35 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 36
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 92.11 %
Recall (true positives / (true positives + false negatives)) 49.30 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 35 sequences 

4HBDH_CLOK5 (P38945), ADH1_CLOSA  (P13604), ADH2_ECOLI  (P37686), 

ADH2_ENTH1  (Q24803), ADH2_GEOTN  (A4ISB9), ADH2_ZYMMA  (F8DVL8), 
ADH2_ZYMMO  (P0DJA2), ADH3_ENTH1  (Q24857), ADH4_SCHPO  (Q09669), 
ADH4_YEAS7  (A6ZTT5), ADH4_YEAST  (P10127), ADHA_CLOAB  (Q04944), 
ADHB_CLOAB  (Q04945), ADHE_ECO57  (P0A9Q8), ADHE_ECOLI  (P0A9Q7), 
ADHE_STRP2  (A0A0H2ZM56), ADHE_STRPN  (A0A0H2URT2), DHAT_CITFR  (P45513), 
DHAT_KLEPN  (Q59477), EUTG_ECOLI  (P76553), EUTG_SALTY  (P41795), 
FUCO_ECO57  (P0A9S2), FUCO_ECOLI  (P0A9S1), GBSB_BACSU  (P71017), 
GLDA_CITFR  (P45511), GLDA_ECOL6  (P0A9S6), GLDA_ECOLI  (P0A9S5), 
GLDA_GEOSE  (P32816), GLDA_PSEPU  (P50173), GLDA_THEMA  (Q9WYQ4), 
GLYAR_HALSA (Q9HHR2), MEDH_BACMT  (P31005), YQHD_ECOLI  (Q46856), 
YUGJ_BACSU  (O05239), YUGK_BACSU  (O05240)
» more

UniProtKB/Swiss-Prot
False negative sequences		 36 sequences 

4HBDH_CUPNE (Q59104), ADH1_GEOTN  (A4IP64), ADHA_THEET  (Q9F282), 

ADHE_CLOAB  (P33744), ADH_THEBA   (A0A0S1X9S7), CLCE_PSEAI  (O87612), 
CLCE_PSEKB  (O30847), GRAC_RHIS5  (A1IIX4), HCXA_ECOLI  (P45579), 
HOT_AEDAE   (Q17EN4), HOT_ANOGA   (Q7Q547), HOT_BOVIN   (A6QP15), 
HOT_CAEBR   (A8WTJ7), HOT_CAEEL   (Q9U2M4), HOT_DICDI   (Q54GJ7), 
HOT_DROME   (Q9W265), HOT_DROPS   (Q28XT3), HOT_HUMAN   (Q8IWW8), 
HOT_MOUSE   (Q8R0N6), HOT_PONAB   (Q5RF11), HOT_RAT (Q4QQW3), 
HOT_XENLA   (Q08B39), HOT_XENTR   (Q6P371), KDNB_SHEON  (Q8EEB0), 
LINF_SPHIU  (Q5W9E3), MACA1_RHOOP (O84992), MNO_RHOER   (Q53062), 
PHPC_STRVT  (D9XF45), SARD_BILW3  (E5Y946), SQWF_CLOS9  (J1H1J3), 
TCBF_PSESQ  (P27101), TFDF1_CUPPJ (P27137), TFDF2_CUPPJ (P94135), 
TFDF_DELAC  (Q93T12), TFTE_BURCE  (Q45072), Y1167_SYNY3 (P74246)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

MACA2_RHOOP (P56870)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			3 sequences
			


			
CAP2_HUMAN  (P40123), CAP2_PONAB  (Q5R5X8), GIF1_ORYSJ  (Q6AVI1)


				
	

	

		PDB
[Detailed view]		
		
			33 PDB
			


			1JPU; 1JQ5; 1JQA; 1KQ3; 1OJ7; 1RRM; 2BI4; 2BL4; 3BFJ; 3OWO; 3OX4; 4QGS; 
			
				5BR4; 5ZXL; 6AHC; 6SCG; 6SCI; 6TQH; 6TQM; 7BVP; 7QLG; 7QLQ; 7QLS; 7QNF; 
				7QNH; 7QNI; 7QNJ; 7R0P; 7R3D; 7R5T; 8GOA; 8GOB; 8X6M
			
			

			» more