PROSITE entry PS00071
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Direct ScanProsite submission
General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS00071 |
| Entry name [info] | GAPDH |
| Accession [info] | PS00071 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00069 |
| Associated ProRule [info] | PRU10009 |
Name and characterization of the entry
| Description [info] | Glyceraldehyde 3-phosphate dehydrogenase active site. |
| Pattern [info] |
[ASV]-S-C-[NT]-T-{S}-x-[LIM].
|
Numerical results [info]
| Total number of hits | 409 in 409 different sequences |
| Number of true positive hits | 393 in 393 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 16 in 16 different sequences |
| Number of false negative sequences | 25 |
| Number of 'partial' sequences | 9 |
| Precision (true positives / (true positives + false positives)) | 96.09 % |
| Recall (true positives / (true positives + false negatives)) | 94.02 % |
Comments [info]
| Taxonomic range [info] | Archaea, Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 3 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
393 sequences
E4PD_CITK8 (A8APE1), E4PD_CROS8 (A7MJQ2), E4PD_ECO24 (A7ZR35), E4PD_ECO27 (B7UHW9), E4PD_ECO45 (B7MMA9), E4PD_ECO55 (B7LFI3), E4PD_ECO57 (P0A9B8), E4PD_ECO5E (B5YQB9), E4PD_ECO7I (B7NHY6), E4PD_ECO81 (B7MZM0), E4PD_ECO8A (B7LYU4), E4PD_ECOBW (C5A0J7), E4PD_ECODH (B1XEL0), E4PD_ECOHS (A8A467), E4PD_ECOK1 (A1AFB1), E4PD_ECOL5 (Q0TDS9), E4PD_ECOL6 (P0A9B7), E4PD_ECOLC (B1IT76), E4PD_ECOLI (P0A9B6), E4PD_ECOLU (B7N7H3), E4PD_ECOSE (B6I761), E4PD_ECOSM (B1LDD2), E4PD_ECOUT (Q1R7A6), E4PD_EDWI9 (C5BAU7), E4PD_ENT38 (A4WE72), E4PD_ERWT9 (B2VF24), E4PD_ESCF3 (B7LPD5), E4PD_KLEP3 (B5XUB7), E4PD_KLEP7 (A6TDT2), E4PD_PECAS (Q6D086), E4PD_PECCP (C6DFH8), E4PD_PHOLL (Q7N7Z6), E4PD_PROMH (B4EUH7), E4PD_PSYIN (A1SVN9), E4PD_SALA4 (B5F5J5), E4PD_SALAR (A9MRF0), E4PD_SALCH (Q57K44), E4PD_SALDC (B5FUI3), E4PD_SALEP (B5QXJ7), E4PD_SALG2 (B5RE31), E4PD_SALHS (B4THF4), E4PD_SALNS (B4T5H2), E4PD_SALPA (Q5PJI5), E4PD_SALPB (A9N3Q6), E4PD_SALPC (C0PY46), E4PD_SALPK (B5BFN5), E4PD_SALSV (B4TV39), E4PD_SALTI (Q8XGA4), E4PD_SALTY (Q7CPU5), E4PD_SHEAM (A1S9A4), E4PD_SHEB2 (B8E5U5), E4PD_SHEDO (Q12QA4), E4PD_SHEFN (Q087Q7), E4PD_SHEHH (B0TUC0), E4PD_SHELP (A3QAX7), E4PD_SHEON (Q8EIB2), E4PD_SHEPA (A8H0M9), E4PD_SHEPC (A4Y3R9), E4PD_SHEPW (B8CU41), E4PD_SHESA (A0L0K7), E4PD_SHESM (Q0HM63), E4PD_SHESR (Q0HRM3), E4PD_SHESW (A1RN69), E4PD_SHIB3 (B2U0U3), E4PD_SHIBS (Q31WI6), E4PD_SHIDS (Q32BY7), E4PD_SHIF8 (Q0T0X3), E4PD_SHIFL (P0A9B9), E4PD_SHISS (Q3YXU5), E4PD_YERE8 (A1JPR1), E4PD_YERPA (Q1CB62), E4PD_YERPE (Q7CGS4), E4PD_YERPN (Q1CEY2), E4PD_YERPS (Q666Q0), G3P1_AGABI (P32635), G3P1_BACCE (Q4MQ58), G3P1_BACSU (P09124), G3P1_CAEEL (P04970), G3P1_CANGA (Q6FPW3), G3P1_DROME (P07486), G3P1_ECO57 (P0A9B4), G3P1_ECOLI (P0A9B2), G3P1_GIAIN (P53429), G3P1_GLORO (O16027), G3P1_KLULA (P17819), G3P1_KLUMA (P84998), G3P1_METAC (P58837), G3P1_METBF (Q46AH5), G3P1_MUCCL (Q9C136), G3P1_NOSS1 (P80506), G3P1_SCHPO (P78958), G3P1_STAAC (Q5HHP5), G3P1_STAAM (P0A036), G3P1_STAAN (P99136), G3P1_STAAR (Q6GIL8), G3P1_STAAS (Q6GB58), G3P1_STAAW (P0A037), G3P1_STAEQ (Q5HQV4), G3P1_STAES (Q8CPY5), G3P1_STRAE (P54226), G3P1_STRAW (Q82IZ2), G3P1_SYNY3 (P49433), G3P1_TRIKO (P17729), G3P1_TRIV2 (P34916), G3P1_YEAST (P00360), G3P2_AGABI (P32636), G3P2_BACSU (O34425), G3P2_CAEBR (P32809), G3P2_CAEEL (P17329), G3P2_CANGA (Q6FSM4), G3P2_DANRE (Q5MJ86), G3P2_DROME (P07487), G3P2_DROPS (O44104), G3P2_DROSU (O44105), G3P2_ECO57 (P58072), G3P2_KLULA (Q6CX23), G3P2_KLUMA (Q01077), G3P2_METAC (P58838), G3P2_METBF (Q465K9), G3P2_MUCCL (Q96UF2), G3P2_NOSS1 (P58554), G3P2_SCHPO (O43026), G3P2_STAAC (Q5HF86), G3P2_STAAM (P64180), G3P2_STAAN (P99067), G3P2_STAAR (Q6GG19), G3P2_STAAS (Q6G8N9), G3P2_STAAW (P64181), G3P2_STAEQ (Q5HNL7), G3P2_STAES (Q8CNY0), G3P2_STRAE (E3VWI2), G3P2_SYNY3 (P80505), G3P2_TRIKO (P17730), G3P2_TRIV2 (P34917), G3P2_YEAST (P00358), G3P3_CAEBR (P32810), G3P3_CAEEL (P17330), G3P3_KLUMA (P84999), G3P3_MUCCL (Q96UF1), G3P3_NOSS1 (P58559), G3P3_TRIV2 (P34918), G3P3_YEAST (P00359), G3P4_CAEEL (P17331), G3PA1_ARATH (P25856), G3PA2_ARATH (Q9LPW0), G3PA_CHLRE (P50362), G3PA_CHOCR (P34919), G3PA_GRAGA (P30724), G3PA_GUITH (O09452), G3PA_MAIZE (P09315), G3PA_PEA(P12858), G3PA_SCEVA (Q8VXQ9), G3PA_SINAL (P09672), G3PA_SPIOL (P19866), G3PA_TOBAC (P09043), G3PB_ARATH (P25857), G3PB_PEA(P12859), G3PB_SPIOL (P12860), G3PB_TOBAC (P09044), G3PC1_ARATH (P25858), G3PC1_HORVU (P26517), G3PC1_MAIZE (P08735), G3PC1_ORYSJ (Q0J8A4), G3PC2_ARATH (Q9FX54), G3PC2_MAIZE (Q09054), G3PC2_ORYSJ (Q7FAH2), G3PC3_MAIZE (Q43247), G3PC3_ORYSJ (Q6K5G8), G3PC_ANTMA (P25861), G3PC_CHLRE (P49644), G3PC_CHOCR (P34920), G3PC_CRAPL (Q42671), G3PC_CUPNH (P50321), G3PC_DIACA (P34921), G3PC_GINBI (Q39769), G3PC_GRAGA (P54270), G3PC_LEIME (Q01558), G3PC_MAGLI (P26518), G3PC_MESCR (P17878), G3PC_ORYSI (A2YQT7), G3PC_PEA(P34922), G3PC_PETCR (P26519), G3PC_PETHY (P26520), G3PC_PHYPA (P34923), G3PC_PINSY (P34924), G3PC_RANAC (P26521), G3PC_SCEVA (Q8VXQ8), G3PC_SINAL (P04796), G3PC_TAXBA (Q41595), G3PC_TOBAC (P09094), G3PC_TRYBB (P10097), G3PG_CRIFA (O96423), G3PG_LEIME (Q27890), G3PG_TRYBB (P22512), G3PG_TRYCR (P22513), G3PP1_ARATH (Q9SAJ6), G3PP2_ARATH (Q5E924), G3PP_CUPNH (P50322), G3PT_BOVIN (Q2KJE5), G3PT_HUMAN (O14556), G3PT_MACFA (Q4R3T1), G3PT_MOUSE (Q64467), G3PT_RAT(Q9ESV6), G3P_AERPE (Q9YFS9), G3P_AJECA (Q9HFX1), G3P_AMAMU (P55071), G3P_AQUAE (O67161), G3P_ARCFU (O28542), G3P_ASPNG (Q12552), G3P_ASPOR (Q9HGY7), G3P_ATLHE (P24750), G3P_ATRNU (P34783), G3P_BACFR (Q59199), G3P_BLUHO (Q00640), G3P_BOLED (Q00301), G3P_BORBU (P46795), G3P_BORHE (P46796), G3P_BOVIN (P10096), G3P_BRUMA (P48812), G3P_BUCAI (P57384), G3P_BUCAP (Q07234), G3P_BUCBP (Q89AK1), G3P_CANAW (Q92211), G3P_CANLF (Q28259), G3P_CERSP (P29272), G3P_CHICK (P00356), G3P_CHLMU (Q9PJN6), G3P_CHLPN (Q9Z7T0), G3P_CHLT2 (B0B879), G3P_CHLTR (P0CE13), G3P_CITFR (P24748), G3P_CLAP2 (Q00584), G3P_CLOAB (O52631), G3P_CLOPA (Q59309), G3P_COCHE (P29497), G3P_COCIM (Q1DTF9), G3P_COCLU (P28844), G3P_COCP7 (Q8J1H3), G3P_COLGL (P35143), G3P_COLLI (O57479), G3P_COLLN (P54117), G3P_CORGL (Q01651), G3P_COTJA (Q05025), G3P_CRIGR (P17244), G3P_CRYNB (P0CN75), G3P_CRYNJ (P0CN74), G3P_CRYPA (P19089), G3P_CUTCU (Q9Y796), G3P_DANRE (Q5XJ10), G3P_DEBHA (Q6BMK0), G3P_DICDI (Q94469), G3P_DROHY (Q01597), G3P_ECHMU (Q27652), G3P_ECOL6 (P0A9B3), G3P_EMENI (P20445), G3P_EREGS (Q757I2), G3P_ESCF3 (B7LQ20), G3P_ESCFE (P0C8Z1), G3P_FELCA (Q9N2D5), G3P_GEOSE (P00362), G3P_GLOMM (Q4U3L0), G3P_HAEIN (P44304), G3P_HALMA (Q5V061), G3P_HALS3 (B0R2M2), G3P_HALSA (Q9HSS7), G3P_HALVA (Q48335), G3P_HELPJ (Q9ZKT0), G3P_HELPY (P55971), G3P_HEYCO (P15115), G3P_HOMAM (P00357), G3P_HUMAN (P04406), G3P_HYPAT (P87197), G3P_HYPBU (A2BLC6), G3P_JACOR (P80534), G3P_KITAU (Q59800), G3P_KLEPN (P24164), G3P_LACDT (P55070), G3P_LENED (Q9UR38), G3P_LYOSH (Q92243), G3P_MASBA (Q9N655), G3P_MESAU (P51640), G3P_META3 (A6UUN9), G3P_METB6 (A7IB57), G3P_METBR (P19314), G3P_METBU (Q12XM4), G3P_METFE (P10618), G3P_METFO (P19315), G3P_METHJ (Q2FNA2), G3P_METJA (Q58546), G3P_METKA (P58839), G3P_METM5 (A4FZL2), G3P_METM6 (A9A6M9), G3P_METM7 (A6VIW4), G3P_METMA (Q8PTD3), G3P_METMP (Q6M0E6), G3P_METS3 (A5ULT9), G3P_METS5 (A4YHA5), G3P_METST (Q2NEN0), G3P_METTH (O27090), G3P_METVS (A6URW1), G3P_MONPU (P53430), G3P_MOUSE (P16858), G3P_MUSPF (A3FKF7), G3P_MYCAV (P94915), G3P_MYCBO (P64179), G3P_MYCBP (A0A0H3MAB5), G3P_MYCGE (P47543), G3P_MYCLE (P46713), G3P_MYCMD (P09317), G3P_MYCPN (P75358), G3P_MYCS2 (A0QWW2), G3P_MYCTO (P9WN82), G3P_MYCTU (P9WN83), G3P_NATPD (Q3IUT3), G3P_NEUCR (P54118), G3P_OGAPD (O59841), G3P_OMPOL (Q8TFJ2), G3P_ONCMY (O42259), G3P_ONCVO (O01360), G3P_PANVR (P56649), G3P_PARBA (Q8X1X3), G3P_PELSI (Q5R2J2), G3P_PHACH (Q01982), G3P_PHANO (Q9P8C0), G3P_PHARH (O13507), G3P_PHYIN (P26988), G3P_PICPA (Q92263), G3P_PICTO (Q6L125), G3P_PIG (P00355), G3P_PODAS (P32637), G3P_PONAB (Q5RAB4), G3P_PRIM3 (P23722), G3P_PSEAE (P27726), G3P_PSEVU (P24751), G3P_PYRAB (Q9V1P1), G3P_PYRAE (Q8ZWK7), G3P_PYRAR (A4WIW2), G3P_PYRCJ (A3MTU1), G3P_PYRFU (P61879), G3P_PYRHO (O59494), G3P_PYRIL (A1RV79), G3P_PYRNV (B1YD06), G3P_PYRWO (P61880), G3P_RABIT (P46406), G3P_RALN1 (P52694), G3P_RAT (P04797), G3P_RHIMI (Q8NK47), G3P_SACS2 (P39460), G3P_SALTI (P0A1P1), G3P_SALTY (P0A1P0), G3P_SCHCO (P32638), G3P_SCHMA (P20287), G3P_SCLSC (Q96US8), G3P_SERMA (P24166), G3P_SEROD (P24753), G3P_SHEEP (Q28554), G3P_SHIBC (I2BA89), G3P_SHIBL (P0DJO7), G3P_SHIFL (P0A9B5), G3P_SORMA (Q8WZN0), G3P_SPECI (Q4KYY3), G3P_STAAU (P0A038), G3P_STREQ (Q59906), G3P_STRP1 (P0C0G7), G3P_STRP3 (P0DB18), G3P_STRP6 (Q5XDW3), G3P_STRP8 (P68777), G3P_STRPQ (P0DB19), G3P_STRPY (P0C0G6), G3P_SULAC (Q4J940), G3P_SULIA (C3N6F0), G3P_SULIK (C4KHW5), G3P_SULIL (C3MQN0), G3P_SULIM (C3MWN0), G3P_SULIN (C3NGT6), G3P_SULIY (C3NEV8), G3P_SULTO (Q971K2), G3P_THEAC (Q9HJ69), G3P_THEAQ (P00361), G3P_THEKO (Q5JHB5), G3P_THEMA (P17721), G3P_THEON (B6YUU0), G3P_THESM (C6A312), G3P_THEVO (Q97BJ8), G3P_TREPA (O83816), G3P_WICCF (Q9UVC0), G3P_XANFL (P51009), G3P_XENLA (P51469), G3P_YARLI (Q6CCU7), G3P_ZYGRO (P08439), G3P_ZYMMO (P09316), GAP2_PSEAB (Q02PG5), HEPG_ASPOR (Q2U0J7)» more
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| UniProtKB/Swiss-Prot False negative sequences |
25 sequences
E4PD_AERHH (A0KGD2), E4PD_AERS4 (A4SRF2), E4PD_ALIF1 (Q5E7R0), E4PD_ALIFM (B5F9T4), E4PD_ALISL (B6EMW1), E4PD_ALTMD (B4RWC5), E4PD_COLP3 (Q47XD5), E4PD_IDILO (Q5QVL6), E4PD_PHOPR (Q6LMN0), E4PD_PSEA6 (Q15QK3), E4PD_PSET1 (Q3ILL8), E4PD_TOLAT (C4L9J3), E4PD_VIBC1 (A7MTQ2), E4PD_VIBC3 (A5F9G1), E4PD_VIBCH (P0C6C2), E4PD_VIBPA (Q87LL0), E4PD_VIBVU (Q8DCA1), E4PD_VIBVY (Q7MHL0), G3P_KLEAE (P24163), G3P_LACDE (O32755), G3P_LACLA (P52987), G3P_MELGA (O57672), G3P_METMJ (A3CYG8), G3P_PLESA (Q9UW96), G3P_STRCO (Q9Z518)» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
9 sequences
G3P2_BACCE (P83077), G3PB_POPEU (P84544), G3PC2_HORVU (P08477), G3PC_PSEMZ (P85954), G3PT_MESAU (P86211), G3P_CAVPO (P70685), G3P_CHAMQ (C0HLQ6), G3P_NAEFO (P83601), PS5_PINST (P84721)» more |
| UniProtKB/Swiss-Prot False positive sequences |
16 sequences
BLAA_STRCI (P33651), CARL1_MOUSE (Q6EDY6), DDB1_DROME (Q9XYZ5), ERYA1_SACER (Q03131), GNKL2_PICSI (D5A8I3), MATK_VACFA (Q6E4Q3), NU133_DROME (Q9VCW3), PATB_ASPCL (A1CFK9), PGLR1_COLLN (Q00446), RBL4_ARATH (F4JBM4), RIBZ_CLOD6 (Q180E3), RL7L_HUMAN (Q6DKI1), SIBD_DICDI (Q54JA4), SIK3_DANRE (Q6NSM8), TGFB3_CHICK (P16047), XYLT_DROME (Q7KVA1)» more |
| PDB [Detailed view] |
142 PDB
1A7K; 1B7G; 1CER; 1CF2; 1CRW; 1DBV; 1DC3; 1DC4; 1DC5; 1DC6; 1DSS; 1GAD; 1GAE; 1GD1; 1GPD; 1GYP; 1GYQ; 1HDG; 1I32; 1I33; 1IHX; 1IHY; 1J0X; 1JN0; 1K3T; 1ML3; 1NBO; 1QXS; 1RM3; 1RM4; 1RM5; 1S7C; 1SZJ; 1U8F; 1ZNQ; 2CZC; 2DBV; 2EP7; 2G82; 2GD1; 2HKI; 2I5P; 2PKQ; 2PKR; 2VYN; 2VYV; 2X0N; 2X5J; 2XF8; 2YYY; 3CMC; 3DBV; 3DMT; 3E5R; 3E6A; 3GPD; 3H9E; 3HJA; 3IDS; 3K2B; 3K73; 3L6O; 3LC1; 3LC2; 3LC7; 3LVF; 3PFW; 3PYM; 3QV1; 3RVD; 3V1Y; 3VAZ; 4DBV; 4GPD; 4IQ8; 4K9D; 4O59; 4O63; 4WNC; 4WNI; 4Z0H; 5C7I; 5C7L; 5C7O; 5DDI; 5O0V; 5T73; 5TSO; 5ZA0; 6ADE; 6FZH; 6IO4; 6IO6; 6IOJ; 6IQ6; 6ITE; 6KEZ; 6LGJ; 6M61; 6OK4; 6QUN; 6QUQ; 6UTM; 6UTN; 6UTO; 6WYC; 6X2E; 6YND; 6YNE; 6YNF; 6YNH; 7JH0; 7JWK; 7Q53; 7Q54; 7Q55; 7Q56; 7Q57; 7U4S; 7U5M; 7ZQ3; 7ZQ4; 7ZQK; 8BR4; 8DE5; 8DNS; 8G12; 8G13; 8G14; 8G15; 8G16; 8G17; 8HRO; 8HRP; 8HRQ; 8HRR; 8HRS; 8HRT; 8I7E; 8JZJ; 8P5F; 8WWZ » more |