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Entry: PS00075

General information about the entry

Entry name [info] DHFR_1
Accession [info] PS00075
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1997 DATA UPDATE;
17-JUN-2020 INFO UPDATE.
PROSITE Doc. [info] PDOC00072

Name and characterization of the entry

Description [info] Dihydrofolate reductase (DHFR) domain signature.
Pattern [info]
[LVAGC]-[LIF]-G-x(4)-[LIVMF]-P-W-x(4,5)-[DE]-x(3)-[FYIV]-x(3)-[STIQ].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2020_03 which contains 562'755 sequence entries.


Total number of hits 93 in 93 different sequences
Number of true positive hits 90 in 90 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 6
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 96.77 %
Recall (true positives / (true positives + false negatives)) 93.75 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
90 sequences

DRTS1_ARATH (Q05762    ), DRTS2_ARATH (Q05763    ), DRTS_DAUCA  (P45350    ), 
DRTS_LEIAM  (P16126    ), DRTS_LEIMA  (P07382    ), DRTS_MAIZE  (O81395    ), 
DRTS_ORYSJ  (Q2QRX6    ), DRTS_PARTE  (Q27828    ), DRTS_PLABA  (Q27713    ), 
DRTS_PLACH  (P20712    ), DRTS_PLAFK  (P13922    ), DRTS_PLAVI  (O02604    ), 
DRTS_PLAVN  (P46103    ), DRTS_SOYBN  (P51820    ), DRTS_TOXGO  (Q07422    ), 
DRTS_TRYBB  (Q27783    ), DRTS_TRYCR  (Q27793    ), DYR10_ECOLX (Q04515    ), 
DYR13_ECOLX (Q59408    ), DYR15_ECOLX (P78218    ), DYR1_ECOLX  (P00382    ), 
DYR1_HALMA  (Q5V3R2    ), DYR2_HALMA  (Q5V600    ), DYR3_SALTM  (P12833    ), 
DYR5_ECOLX  (P11731    ), DYR6_PROMI  (P95524    ), DYR7_ECOLX  (P27422    ), 
DYR8_ECOLX  (P0ABQ7    ), DYR8_SHISO  (P0ABQ8    ), DYR9_ECOLX  (Q59397    ), 
DYRA_HALVD  (P15093    ), DYRA_STAAU  (P13955    ), DYRB_HALVO  (Q9UWQ4    ), 
DYR_AEDAL   (P28019    ), DYR_BACSU   (P11045    ), DYR_BOVIN   (P00376    ), 
DYR_BPT4    (P04382    ), DYR_BUCAI   (P57243    ), DYR_BUCAP   (Q8K9Z8    ), 
DYR_BUCBP   (Q89AV2    ), DYR_CAEEL   (Q93341    ), DYR_CANAX   (P22906    ), 
DYR_CHICK   (P00378    ), DYR_CITFR   (P31073    ), DYR_CRYNJ   (Q07801    ), 
DYR_DROME   (P17719    ), DYR_ECOL6   (P0ABQ5    ), DYR_ECOLI   (P0ABQ4    ), 
DYR_ENTFC   (P00380    ), DYR_HAEIN   (P43791    ), DYR_HELVI   (Q9U8B8    ), 
DYR_HHV8P   (Q2HRC6    ), DYR_HUMAN   (P00374    ), DYR_KLEAE   (P31074    ), 
DYR_LACCA   (P00381    ), DYR_LACLA   (Q59487    ), DYR_MESAU   (P04753    ), 
DYR_MOUSE   (P00375    ), DYR_MYCBO   (P0A547    ), DYR_MYCGE   (P47470    ), 
DYR_MYCLE   (Q9CBW1    ), DYR_MYCPN   (P78028    ), DYR_MYCPU   (Q98Q32    ), 
DYR_MYCTO   (P9WNX0    ), DYR_MYCTU   (P9WNX1    ), DYR_NEIGO   (P04174    ), 
DYR_NEIMA   (Q9JSQ9    ), DYR_NEIMB   (Q9K168    ), DYR_PIG     (P00377    ), 
DYR_PNECA   (P16184    ), DYR_RAT     (Q920D2    ), DYR_SCHMA   (G4VJD6    ), 
DYR_SCHPO   (P36591    ), DYR_SHIFL   (P0ABQ6    ), DYR_SHV21   (P09503    ), 
DYR_SHV24   (P27421    ), DYR_SHV2C   (P22573    ), DYR_STAAC   (Q5HFZ7    ), 
DYR_STAAM   (P0A016    ), DYR_STAAN   (P99079    ), DYR_STAAR   (Q6GGY1    ), 
DYR_STAAS   (Q6G9D5    ), DYR_STAAU   (P0A017    ), DYR_STAAW   (Q8NWQ9    ), 
DYR_STAEP   (P0C0P0    ), DYR_STAEQ   (Q5HPB1    ), DYR_STAES   (P0C0P1    ), 
DYR_STAHA   (Q54277    ), DYR_STRPN   (Q54801    ), DYR_YEAST   (P07807    )
» more

UniProtKB/Swiss-Prot
False negative sequences
6 sequences

DRTS_CRIFA  (Q23695    ), DRTS_MIMIV  (Q5UQG3    ), DYR2_HUMAN  (Q86XF0    ), 
DYR_ENCCU   (O62583    ), DYR_THEMA   (Q60034    ), DYR_UREPA   (Q9PR30    )
» more

UniProtKB/Swiss-Prot
False positive sequences
3 sequences

Y2900_MYCTO (P9WJP8    ), Y2900_MYCTU (P9WJP9    ), Y2924_MYCBO (P65409    )

		

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