PROSITE entry PS00081

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General information about the entry

Entry name [info]	LIPOXYGENASE_2
Accession [info]	PS00081
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-DEC-2004 DATA UPDATE; 08-NOV-2023 INFO UPDATE.
PROSITE Doc. [info]	PDOC00077

Name and characterization of the entry

Description [info]	Lipoxygenases iron-binding region signature 2.
Pattern [info]	[LIVMACST]-H-P-[LIVM]-x-[KRQV]-[LIVMF](2)-x-[AP]-H.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2023_05 which contains 570'420 sequence entries.

Total number of hits	70 in 70 different sequences
Number of true positive hits	70 in 70 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	8
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	89.74 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

70 sequences

ALOX8_MOUSE (O35936), AOSL_PLEHO  (O16025), LOX11_SOLTU (P37831),

LOX12_HUMAN (P18054), LOX12_MOUSE (P39655), LOX12_RAT   (F1LQ70), 
LOX12_SOLTU (O24379), LOX13_SOLTU (Q43189), LOX14_SOLTU (Q43190), 
LOX15_BOVIN (P27479), LOX15_HUMAN (P16050), LOX15_MOUSE (P39654), 
LOX15_PIG   (P16469), LOX15_PONAB (Q5RBE8), LOX15_RABIT (P12530), 
LOX15_RAT   (Q02759), LOX15_SOLTU (Q43191), LOX16_SOLTU (Q41238), 
LOX17_SOLTU (O22507), LOX18_SOLTU (O22508), LOX1_ARATH  (Q06327), 
LOX1_HORVU  (P29114), LOX1_LENCU  (P38414), LOX1_ORYSJ  (Q76I22), 
LOX1_SOYBN  (P08170), LOX1_TANCI  (R9WTS6), LOX21_HORVU (P93184), 
LOX21_SOLTU (O24370), LOX22_HORVU (Q8GSM3), LOX23_HORVU (Q8GSM2), 
LOX2_ARATH  (P38418), LOX2_ORYSJ  (P29250), LOX2_PEA(P14856), 
LOX2_SOYBN  (P09439), LOX2_TANCI  (R9WS04), LOX31_SOLTU (O24371), 
LOX3_ARATH  (Q9LNR3), LOX3_ORYSJ  (Q7G794), LOX3_PEA(P09918), 
LOX3_SOYBN  (P09186), LOX4_ARATH  (Q9FNX8), LOX4_ORYSJ  (Q53RB0), 
LOX4_SOYBN  (P38417), LOX5_ARATH  (Q9LUW0), LOX5_HUMAN  (P09917), 
LOX5_MESAU  (P51399), LOX5_MOUSE  (P48999), LOX5_ORYSJ  (Q7XV13), 
LOX5_RAT(P12527), LOX6_ARATH  (Q9CAG3), LOX6_ORYSJ  (Q8H016), 
LOXA_PHAVU  (P27480), LOXA_PSEAE  (Q9I4G8), LOXA_SOLLC  (P38415), 
LOXB_PHAVU  (P27481), LOXB_SOLLC  (P38416), LOXC1_ORYSJ (P38419), 
LOXC2_ORYSJ (Q84YK8), LOXE3_HUMAN (Q9BYJ1), LOXE3_MOUSE (Q9WV07), 
LOXE3_RAT   (D3ZKX9), LOXX_SOYBN  (P24095), LOX_PSEAI   (Q8RNT4), 
LX12B_HUMAN (O75342), LX12B_MOUSE (O70582), LX12B_RAT   (Q2KMM4), 
LX12E_MOUSE (P55249), LX12E_RAT   (D3ZQF9), LX15B_HUMAN (O15296), 
LX15B_RAT   (Q8K4F2)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

8 sequences

LILIP_NOSS1 (Q8YK97), MNLOX_ASPFU (Q4WA38), MNLOX_COLGC (T0JRM4),

MNLOX_FUSOF (F9FRH4), MNLOX_GAEAV (Q8X151), MNLOX_GAETR (Q8X150), 
MNLOX_MAGO7 (G4NAP4), MNLOX_NAKOS (P0CT92)

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PDB
[Detailed view]

59 PDB

1F8N; 1FGM; 1FGO; 1FGQ; 1FGR; 1FGT; 1HU9; 1IK3; 1JNQ; 1LNH; 1LOX; 1N8Q; 1NO3; 1ROV; 1RRH; 1RRL; 1Y4K; 1YGE; 2FNQ; 2IUK; 2P0M; 2SBL; 3BNB; 3BNC; 3BND; 3BNE; 3D3L; 3DY5; 3FG1; 3FG3; 3FG4; 3O8Y; 3PZW; 3RDE; 3V92; 3V98; 3V99; 4G32; 4G33; 4NRE; 4QWT; 4RPE; 4WFO; 4WHA; 5EEO; 5IR4; 5IR5; 5LC8; 5T5V; 5TQN; 5TQO; 5TQP; 5TR0; 6N2W; 6NCF; 7LAF; 7TTJ; 7TTK; 7TTL
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