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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00091


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PURL: https://purl.expasy.org/prosite/signature/PS00091

Direct ScanProsite submission
General information about the entry

Entry name [info] THYMIDYLATE_SYNTHASE
Accession [info] PS00091
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00086
Associated ProRule [info] PRU10016

Name and characterization of the entry

Description [info] Thymidylate synthase active site.
Pattern [info] 
R-x(2)-[LIVMT]-x(2,3)-[FWY]-[QNYDI]-x(8,13)-[LVESI]-x-P-C-[HAVMLC]-x(3)-
[QMTLHD]-[FYWL]-x(0,1)-[LV].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 404 in 404 different sequences
Number of true positive hits 403 in 403 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 49
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.75 %
Recall (true positives / (true positives + false negatives)) 89.16 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 11
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 403 sequences 

DRTS1_ARATH (Q05762), DRTS2_ARATH (Q05763), DRTS_CRIFA  (Q23695), 

DRTS_DAUCA  (P45350), DRTS_LEIAM  (P16126), DRTS_LEIMA  (P07382), 
DRTS_MAIZE  (O81395), DRTS_MIMIV  (Q5UQG3), DRTS_ORYSJ  (Q2QRX6), 
DRTS_PARTE  (Q27828), DRTS_PLABA  (Q27713), DRTS_PLACH  (P20712), 
DRTS_PLAFK  (P13922), DRTS_PLAVI  (O02604), DRTS_SOYBN  (P51820), 
DRTS_TOXGO  (Q07422), DRTS_TRYBB  (Q27783), DRTS_TRYCR  (Q27793), 
TYS1_ENCCU  (O62584), TYS3_ENCCU  (Q8SRG2), TYSY1_BACAM (O30397), 
TYSY1_BACSH (E0TVT6), TYSY1_BACSU (P0CI79), TYSY2_BACAM (P54081), 
TYSY2_BACSH (E0U0H8), TYSY2_BACSU (P11044), TYSY_ACHLI  (A9NG27), 
TYSY_ACIAD  (Q6FER7), TYSY_ACIB3  (B7H0P4), TYSY_ACIB5  (B7I4U0), 
TYSY_ACISJ  (A1W5A4), TYSY_AERHH  (A0KG32), TYSY_AERS4  (A4SIW7), 
TYSY_AFIC5  (B6JB67), TYSY_AGABI  (Q9P4T7), TYSY_AGRFC  (Q8UDS3), 
TYSY_ALBFT  (Q21U56), TYSY_ALIF1  (Q5E7P1), TYSY_ALKEH  (Q0ABR1), 
TYSY_ALLAM  (B9JXQ5), TYSY_ANOFW  (B7GI39), TYSY_AROAE  (Q5P233), 
TYSY_ARTS2  (A0JZC7), TYSY_ASCSU  (O96650), TYSY_AYWBP  (Q2NJ46), 
TYSY_AZOSB  (A1KAF7), TYSY_AZOVD  (C1DK16), TYSY_BACAH  (A0RDL9), 
TYSY_BACAN  (Q81R23), TYSY_BACAT  (O30394), TYSY_BACC1  (Q738X7), 
TYSY_BACCN  (A7GP90), TYSY_BACCR  (Q81E05), TYSY_BACCZ  (Q63BV5), 
TYSY_BACFN  (Q5L9L6), TYSY_BACFR  (Q64PV5), TYSY_BACHK  (Q6HJC7), 
TYSY_BACLD  (Q65J44), TYSY_BACLI  (Q59212), TYSY_BACMO  (Q9ANR7), 
TYSY_BACNA  (Q5D189), TYSY_BACP2  (A8FEB9), TYSY_BACTN  (Q8A639), 
TYSY_BACVZ  (A7Z5T3), TYSY_BARBK  (A1UTA5), TYSY_BARHE  (Q6G2S8), 
TYSY_BARQU  (Q6FZ91), TYSY_BAUCH  (Q1LSU0), TYSY_BDEBA  (Q6MID2), 
TYSY_BIFLO  (Q8G3T9), TYSY_BORBR  (Q7WP13), TYSY_BORPA  (Q7W1A9), 
TYSY_BORPE  (Q7VUE3), TYSY_BOVIN  (Q2TA32), TYSY_BPPHT  (P07606), 
TYSY_BPT4   (P00471), TYSY_BRADU  (Q89G35), TYSY_BRAHW  (C0QWM9), 
TYSY_BRASB  (A5EPD3), TYSY_BRASO  (A4YZC4), TYSY_BREBN  (C0ZI91), 
TYSY_BRUA2  (Q2YS22), TYSY_BRUA4  (A6WZV4), TYSY_BRUAB  (Q57CA9), 
TYSY_BRUC2  (A9M657), TYSY_BRUMB  (C0RE38), TYSY_BRUME  (P67042), 
TYSY_BRUO2  (A5VRE7), TYSY_BRUSI  (B0CHI7), TYSY_BRUSU  (P67043), 
TYSY_BUCA5  (B8D9L8), TYSY_BUCAI  (P57515), TYSY_BUCAP  (Q8K9C3), 
TYSY_BUCAT  (B8D7X0), TYSY_BUCBP  (P59427), TYSY_CANAL  (P12461), 
TYSY_CAUVC  (Q9A6H0), TYSY_CERS1  (A3PLD1), TYSY_CERS4  (Q3J0W9), 
TYSY_CERS5  (A4WQT6), TYSY_CHESB  (Q11HI0), TYSY_CHRSD  (Q1QUD9), 
TYSY_CHRVO  (Q7NZ95), TYSY_CITK8  (A8AP42), TYSY_CLOAB  (Q97EV3), 
TYSY_CLOB8  (A6M378), TYSY_CORA7  (C3PEY5), TYSY_CORDI  (Q6NIF2), 
TYSY_COREF  (Q8FR47), TYSY_CORGB  (A4QCI7), TYSY_CORGL  (Q8NS38), 
TYSY_CORJK  (Q4JX59), TYSY_COXBN  (A9KF61), TYSY_COXBR  (A9N980), 
TYSY_COXBU  (Q83BG2), TYSY_CROS8  (A7MR31), TYSY_CRYNB  (P0CS13), 
TYSY_CRYNJ  (P0CS12), TYSY_CUPMC  (Q1LK81), TYSY_CUPNH  (Q0K889), 
TYSY_CUTAK  (Q6A761), TYSY_CYTH3  (Q11VK5), TYSY_DECAR  (Q47II1), 
TYSY_DEIDV  (C1D070), TYSY_DICNV  (A5EVG5), TYSY_DROME  (O76511), 
TYSY_ECO24  (A7ZQT3), TYSY_ECO27  (B7UHP4), TYSY_ECO45  (B7MLH3), 
TYSY_ECO55  (B7LF04), TYSY_ECO57  (P0A886), TYSY_ECO7I  (B7NVX2), 
TYSY_ECO81  (B7MZC6), TYSY_ECO8A  (B7LY83), TYSY_ECOBW  (C4ZZX9), 
TYSY_ECOHS  (A8A3W0), TYSY_ECOK1  (A1AF39), TYSY_ECOL5  (Q0TE05), 
TYSY_ECOL6  (P0A885), TYSY_ECOLC  (B1IU17), TYSY_ECOLI  (P0A884), 
TYSY_ECOLU  (B7N759), TYSY_ECOUT  (Q1R7I6), TYSY_ECTM1  (A4Y044), 
TYSY_EDWI9  (C5BH86), TYSY_EHV2   (Q89940), TYSY_ENT38  (A4WE03), 
TYSY_ENTFA  (Q834R3), TYSY_ESCF3  (B7LNI2), TYSY_EXISA  (C4L1C9), 
TYSY_FUSNN  (Q8RGP6), TYSY_GEOKA  (Q5KZ25), TYSY_GEOSW  (C5DAR2), 
TYSY_GEOTN  (A4INY1), TYSY_GLAP5  (B8F6S2), TYSY_HAEDU  (Q7VMH2), 
TYSY_HAEI8  (Q4QM04), TYSY_HAEIE  (A5UDH0), TYSY_HAEIG  (A5UI47), 
TYSY_HAEIN  (P44420), TYSY_HAHCH  (Q2SA17), TYSY_HALH5  (Q9K7B5), 
TYSY_HALHL  (A1WYP9), TYSY_HAMD5  (C4K7G3), TYSY_HHV8P  (P90463), 
TYSY_HISS1  (Q0I563), TYSY_HISS2  (B0UWT7), TYSY_HSVAT  (P12462), 
TYSY_HUMAN  (P04818), TYSY_HYPNA  (Q0C504), TYSY_IIV6   (Q9WBI3), 
TYSY_KINRD  (A6WGF9), TYSY_KLEP7  (A6TDG3), TYSY_LACAC  (Q5FKL6), 
TYSY_LACCA  (P00469), TYSY_LACDA  (Q1GAP2), TYSY_LACDB  (Q04B29), 
TYSY_LACGA  (Q044A1), TYSY_LACH4  (A8YUW0), TYSY_LACJO  (Q74IU3), 
TYSY_LACLA  (P19368), TYSY_LACLS  (Q02Y43), TYSY_LACP3  (Q039F7), 
TYSY_LACPL  (Q88W05), TYSY_LARHH  (C1D4I5), TYSY_LATSS  (Q38WX8), 
TYSY_LEGPA  (Q5X119), TYSY_LEGPC  (A5II41), TYSY_LEGPH  (Q5ZRL3), 
TYSY_LEGPL  (Q5WSU5), TYSY_LEIXX  (Q6AFI0), TYSY_LEVBA  (Q03S95), 
TYSY_LIGS1  (Q1WU17), TYSY_LIMRD  (A5VJK9), TYSY_LISIN  (Q92AD4), 
TYSY_LISMC  (C1KWH4), TYSY_LISMF  (Q71YE1), TYSY_LISMH  (B8DDM8), 
TYSY_LISMO  (Q8Y626), TYSY_LISW6  (A0AJY0), TYSY_MALP2  (Q8EV81), 
TYSY_MARMS  (A6W1R4), TYSY_METC4  (B7KQG2), TYSY_METFK  (Q9RAM7), 
TYSY_METJA  (Q57931), TYSY_METPP  (A2SHH0), TYSY_METSB  (B8ELI3), 
TYSY_METTM  (P80305), TYSY_MOUSE  (P07607), TYSY_MYCA1  (A0QIU1), 
TYSY_MYCBO  (P67045), TYSY_MYCBP  (A1KMA6), TYSY_MYCBT  (C1AFM7), 
TYSY_MYCGA  (Q9XC19), TYSY_MYCGE  (P47469), TYSY_MYCGI  (A4TCI9), 
TYSY_MYCLE  (Q9CBW0), TYSY_MYCPA  (Q73VZ2), TYSY_MYCPN  (P78029), 
TYSY_MYCPU  (Q98Q31), TYSY_MYCS2  (A0QVR9), TYSY_MYCS5  (Q4A611), 
TYSY_MYCSJ  (A3PYA8), TYSY_MYCSK  (A1UEU8), TYSY_MYCSS  (Q1BA64), 
TYSY_MYCTA  (A5U6B7), TYSY_MYCTO  (P9WFR8), TYSY_MYCTU  (P9WFR9), 
TYSY_MYCUA  (A0PQG7), TYSY_MYCVP  (A1T7P4), TYSY_NEIG1  (Q5F732), 
TYSY_NEIGO  (O33380), TYSY_NEIMA  (Q9JT57), TYSY_NEIMB  (Q9JY72), 
TYSY_NEIMF  (A1KVB3), TYSY_NITEC  (Q0AHA4), TYSY_NITEU  (Q82WU3), 
TYSY_NITHX  (Q1QJT8), TYSY_NITOC  (Q3JEI2), TYSY_NITWN  (Q3SQ36), 
TYSY_NOCFA  (Q5YPL7), TYSY_NOCSJ  (A1SJ31), TYSY_NOVAD  (Q2G6V6), 
TYSY_OCEIH  (Q8EQG0), TYSY_ONYPE  (Q6YQT0), TYSY_PAEAT  (A1R8Y7), 
TYSY_PARC0  (A1TM53), TYSY_PARD8  (A6LIC2), TYSY_PARL1  (A7HVX4), 
TYSY_PARM1  (Q2W7P4), TYSY_PASMU  (P57808), TYSY_PECAS  (Q6D8I6), 
TYSY_PECCP  (C6DAE9), TYSY_PEDPA  (Q03F96), TYSY_PHOLL  (Q7N8U4), 
TYSY_PHOPR  (Q6LUM1), TYSY_PHOV8  (A6L1Q8), TYSY_PNECA  (P13100), 
TYSY_POLAQ  (A4SVT7), TYSY_POLNA  (A1VQZ6), TYSY_POLSJ  (Q12CI6), 
TYSY_PORGI  (Q7MTB5), TYSY_PSEA6  (Q15P51), TYSY_PSEA8  (B7V2Q5), 
TYSY_PSEAB  (Q02U73), TYSY_PSEAE  (Q9I6F1), TYSY_PSEP7  (A6UYE6), 
TYSY_PSET1  (Q3IDN1), TYSY_PSYCK  (Q1Q8B2), TYSY_PSYIN  (A1SS96), 
TYSY_PSYWF  (A5WHY0), TYSY_RALN1  (Q8Y0U6), TYSY_RAT(P45352), 
TYSY_RHIEC  (Q2K6G8), TYSY_RHIJ3  (Q1ME82), TYSY_RHILO  (Q98KH9), 
TYSY_RHIME  (Q92NQ5), TYSY_RHIR8  (B9JH03), TYSY_RHIWR  (A5VCW6), 
TYSY_RHOBA  (Q7UID0), TYSY_RHOJR  (Q0SEI1), TYSY_RHOP2  (Q2IYG7), 
TYSY_RHOP5  (Q07PP0), TYSY_RHOPA  (Q6N447), TYSY_RHOPB  (Q211X8), 
TYSY_RHOPS  (Q134B1), TYSY_RUMCH  (B8I0T8), TYSY_RUTMC  (A1AWQ8), 
TYSY_SALAR  (A9MS82), TYSY_SALCH  (Q57KB6), TYSY_SALPA  (Q5PEN6), 
TYSY_SALPB  (A9N2L7), TYSY_SALPC  (C0PXI9), TYSY_SALTI  (Q8Z412), 
TYSY_SALTY  (Q8ZMA9), TYSY_SCHPO  (Q9UTI7), TYSY_SERP5  (A8GIH7), 
TYSY_SHEAM  (A1S3W8), TYSY_SHEB2  (B8EBR5), TYSY_SHEB5  (A3D1U3), 
TYSY_SHEB8  (A6WKP4), TYSY_SHEB9  (A9L5M3), TYSY_SHEDO  (Q12KG8), 
TYSY_SHEFN  (Q07YY3), TYSY_SHEON  (Q8EH94), TYSY_SHEPC  (A4Y4J1), 
TYSY_SHESA  (A0KZP5), TYSY_SHESM  (Q0HG85), TYSY_SHESR  (Q0HSH8), 
TYSY_SHESW  (A1RME0), TYSY_SHIBS  (Q31XG0), TYSY_SHIDS  (Q32C94), 
TYSY_SHIF8  (Q0T137), TYSY_SHIFL  (P48464), TYSY_SHISS  (Q3YY33), 
TYSY_SHOC1  (Q5WDS1), TYSY_SHV21  (P06854), TYSY_SINFN  (C3MEE8), 
TYSY_SINMW  (A6UB24), TYSY_SODGM  (Q2NRH3), TYSY_SPHAL  (Q1GTH6), 
TYSY_STAA1  (A7X2B3), TYSY_STAA2  (A6U1P7), TYSY_STAA3  (Q2FH11), 
TYSY_STAA8  (Q2FYK5), TYSY_STAA9  (A5ISV8), TYSY_STAAB  (Q2YY40), 
TYSY_STAAC  (Q5HFZ6), TYSY_STAAE  (A6QGX8), TYSY_STAAM  (P67046), 
TYSY_STAAN  (P67047), TYSY_STAAR  (Q6GGY0), TYSY_STAAS  (Q6G9D4), 
TYSY_STAAT  (A8Z406), TYSY_STAAU  (P0A0M5), TYSY_STAAW  (P67048), 
TYSY_STAEQ  (Q5HMP6), TYSY_STAES  (P0C0M5), TYSY_STAHJ  (Q4L6D7), 
TYSY_STAS1  (Q49XN8), TYSY_STRA1  (Q3K0J7), TYSY_STRA3  (Q8E4L6), 
TYSY_STRA5  (Q8DZ07), TYSY_STRGC  (A8AXC2), TYSY_STRMU  (Q8DUI4), 
TYSY_STRP1  (P67051), TYSY_STRP2  (Q04LL8), TYSY_STRP3  (P0DG66), 
TYSY_STRP6  (Q5XCM3), TYSY_STRP7  (C1C631), TYSY_STRP8  (Q8P1D1), 
TYSY_STRPB  (Q1JC96), TYSY_STRPC  (Q1JM80), TYSY_STRPD  (Q1JHC5), 
TYSY_STRPF  (Q1J744), TYSY_STRPG  (A2RF20), TYSY_STRPJ  (B8ZMQ1), 
TYSY_STRPM  (Q48U25), TYSY_STRPN  (P67049), TYSY_STRPQ  (P0DG67), 
TYSY_STRR6  (P67050), TYSY_STRS2  (A4W0V3), TYSY_STRSV  (A3CMU9), 
TYSY_STRSY  (A4VUL1), TYSY_STRT1  (Q5M0S7), TYSY_STRT2  (Q5M5B3), 
TYSY_STRTD  (Q03LN3), TYSY_STRZJ  (C1CD36), TYSY_STRZP  (C1CJD5), 
TYSY_STRZT  (C1CQE7), TYSY_STUS1  (A4VGL9), TYSY_SYMTH  (Q67JQ1), 
TYSY_THIDA  (Q3SH96), TYSY_VESOH  (A5CWK3), TYSY_VIBA3  (B7VJ78), 
TYSY_VIBC1  (A7MXJ9), TYSY_VIBC3  (A5F8Y6), TYSY_VIBCH  (O66108), 
TYSY_VIBCM  (C3LST0), TYSY_VIBPA  (Q87SA0), TYSY_VIBVU  (Q8DER9), 
TYSY_VIBVY  (Q7MNN6), TYSY_VZVD   (P09249), TYSY_VZVO   (Q4JQW2), 
TYSY_WIGBR  (Q8D2N4), TYSY_XANAC  (Q8PP46), TYSY_XANC8  (Q4UR35), 
TYSY_XANCP  (Q8PCE7), TYSY_XANE5  (Q3BX87), TYSY_XANOM  (Q2NZH9), 
TYSY_XANOR  (Q5GWB5), TYSY_XENNA  (Q6REU8), TYSY_XYLFA  (Q9PB13), 
TYSY_XYLFT  (Q87BT4), TYSY_YEAST  (P06785), TYSY_YERE8  (A1JPC9), 
TYSY_YERP3  (A7FFE0), TYSY_YERPA  (Q1CAR9), TYSY_YERPE  (Q8ZHV1), 
TYSY_YERPN  (Q1CFB5), TYSY_YERPP  (A4TLC5), TYSY_YERPS  (Q667F9), 
TYSY_ZYMMO  (Q9Z671)
» more

UniProtKB/Swiss-Prot
False negative sequences		 49 sequences 

DRTS_PLAVN  (P46103), TYSY_ACTSZ  (A6VMA0), TYSY_ALCBS  (Q0VM06), 

TYSY_BART1  (A9IW82), TYSY_CHRFK  (A0LY29), TYSY_COLP3  (Q47Y31), 
TYSY_FLAJ1  (A5FJV8), TYSY_FLAPJ  (A6GWH3), TYSY_FRAP2  (B0TYI1), 
TYSY_FRAT1  (Q14H07), TYSY_FRATF  (A7NB78), TYSY_FRATH  (Q2A486), 
TYSY_FRATN  (A0Q7B4), TYSY_FRATO  (Q0BMM0), TYSY_FRATT  (Q5NFK5), 
TYSY_FRATW  (A4IXE8), TYSY_HALVO  (Q9UWQ5), TYSY_HYDCU  (Q31I55), 
TYSY_IDILO  (Q5R064), TYSY_LEUMM  (Q03YZ8), TYSY_MANSM  (Q65VJ8), 
TYSY_MARN8  (A1U3D8), TYSY_MESFL  (Q6F145), TYSY_METAC  (Q8THH4), 
TYSY_METBF  (Q46E28), TYSY_METBU  (Q12X17), TYSY_METCA  (Q603S2), 
TYSY_METKA  (Q8TVL9), TYSY_METMA  (Q8PXI1), TYSY_METNO  (B8IF20), 
TYSY_METTH  (O26868), TYSY_MYCM1  (Q6KIQ6), TYSY_OENOB  (Q04FR4), 
TYSY_PHYMT  (B3QZX0), TYSY_PSEFS  (C3K3Q8), TYSY_PSEP1  (A5WAK1), 
TYSY_PSEPK  (Q88CN9), TYSY_PSESM  (Q87UL4), TYSY_ROSDO  (Q168V8), 
TYSY_RUEST  (Q1GFV4), TYSY_SACD2  (Q21NW5), TYSY_SHEHH  (B0TIU4), 
TYSY_SHELP  (A3QBR4), TYSY_SHEPA  (A8H1B4), TYSY_SHEPW  (B8CQK7), 
TYSY_SHESH  (A8FSC3), TYSY_TERTT  (C5BMA3), TYSY_THISH  (B8GN06), 
TYSY_TOLAT  (C4LD19)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

TYSY_STAEP  (P0C0M4)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			1 sequence
			


			
DCLK_CAEEL  (Q95QC4)


				
	

	

		PDB
[Detailed view]		
		
			248 PDB
			


			pdb_00001aiq; pdb_00001ajm; pdb_00001an5; pdb_00001aob; pdb_00001axw; pdb_00001b02; pdb_00001bdu; pdb_00001bid; pdb_00001bjg; pdb_00001bko; pdb_00001bkp; pdb_00001bo7; 
			
				pdb_00001bo8; pdb_00001bp0; pdb_00001bp6; pdb_00001bq1; pdb_00001bq2; pdb_00001bsf; pdb_00001bsp; pdb_00001ci7; pdb_00001ddu; pdb_00001dna; pdb_00001ev5; pdb_00001ev8; 
				pdb_00001evf; pdb_00001evg; pdb_00001f28; pdb_00001f4b; pdb_00001f4c; pdb_00001f4e; pdb_00001f4f; pdb_00001f4g; pdb_00001ffl; pdb_00001fwm; pdb_00001hvy; pdb_00001hw3; 
				pdb_00001hw4; pdb_00001hzw; pdb_00001i00; pdb_00001j3i; pdb_00001j3j; pdb_00001j3k; pdb_00001jg0; pdb_00001jmf; pdb_00001jmg; pdb_00001jmh; pdb_00001jmi; pdb_00001jtq; 
				pdb_00001jtu; pdb_00001ju6; pdb_00001juj; pdb_00001jut; pdb_00001kce; pdb_00001kzi; pdb_00001kzj; pdb_00001lca; pdb_00001lcb; pdb_00001lce; pdb_00001nce; pdb_00001nja; 
				pdb_00001njb; pdb_00001njc; pdb_00001njd; pdb_00001nje; pdb_00001qqq; pdb_00001rts; pdb_00001syn; pdb_00001tda; pdb_00001tdb; pdb_00001tdc; pdb_00001tdu; pdb_00001thy; 
				pdb_00001tis; pdb_00001tjs; pdb_00001tlc; pdb_00001tls; pdb_00001trg; pdb_00001tsd; pdb_00001tsl; pdb_00001tsm; pdb_00001tsn; pdb_00001tsv; pdb_00001tsw; pdb_00001tsx; 
				pdb_00001tsy; pdb_00001tsz; pdb_00001tvu; pdb_00001tvv; pdb_00001tvw; pdb_00001vza; pdb_00001vzb; pdb_00001vzc; pdb_00001vzd; pdb_00001vze; pdb_00001ypv; pdb_00001zpr; 
				pdb_00002a9w; pdb_00002aaz; pdb_00002bbq; pdb_00002ftn; pdb_00002fto; pdb_00002ftq; pdb_00002g86; pdb_00002g89; pdb_00002g8a; pdb_00002g8d; pdb_00002g8x; pdb_00002h2q; 
				pdb_00002kce; pdb_00002onb; pdb_00002rd8; pdb_00002rda; pdb_00002tdd; pdb_00002tdm; pdb_00002tsc; pdb_00002tsr; pdb_00002vet; pdb_00002vf0; pdb_00003b5b; pdb_00003b9h; 
				pdb_00003bfi; pdb_00003bhl; pdb_00003bhr; pdb_00003bnz; pdb_00003byx; pdb_00003bz0; pdb_00003c06; pdb_00003c0a; pdb_00003cl9; pdb_00003clb; pdb_00003dg8; pdb_00003dga; 
				pdb_00003eaw; pdb_00003ebu; pdb_00003ed7; pdb_00003edw; pdb_00003ef9; pdb_00003egy; pdb_00003ehi; pdb_00003ejl; pdb_00003gg5; pdb_00003gh0; pdb_00003gh2; pdb_00003h9k; 
				pdb_00003hb8; pdb_00003hbb; pdb_00003ihi; pdb_00003ijz; pdb_00003ik0; pdb_00003ik1; pdb_00003inv; pdb_00003irm; pdb_00003irn; pdb_00003iro; pdb_00003ix6; pdb_00003kgb; 
				pdb_00003n5e; pdb_00003n5g; pdb_00003ob7; pdb_00003qj7; pdb_00003tms; pdb_00003uwl; pdb_00004dq1; pdb_00004e28; pdb_00004e5o; pdb_00004eb4; pdb_00004eck; pdb_00004eil; 
				pdb_00004ein; pdb_00004ez8; pdb_00004fgt; pdb_00004foa; pdb_00004fog; pdb_00004fox; pdb_00004fqs; pdb_00004g2o; pdb_00004g6w; pdb_00004gd7; pdb_00004gev; pdb_00004gyh; 
				pdb_00004h0r; pdb_00004h0u; pdb_00004h1i; pdb_00004isk; pdb_00004jef; pdb_00004kpw; pdb_00004ky4; pdb_00004kya; pdb_00004lrr; pdb_00004o1u; pdb_00004o7u; pdb_00004tms; 
				pdb_00004up1; pdb_00004xsc; pdb_00004xsd; pdb_00004xse; pdb_00005fct; pdb_00005h38; pdb_00005h39; pdb_00005h3a; pdb_00005hs3; pdb_00005j7w; pdb_00005t0l; pdb_00005wrn; 
				pdb_00005x4w; pdb_00005x4x; pdb_00005x4y; pdb_00005x5a; pdb_00005x5d; pdb_00005x5q; pdb_00005x66; pdb_00005x67; pdb_00005x69; pdb_00006aog; pdb_00006aoh; pdb_00006aoi; 
				pdb_00006cdz; pdb_00006f6z; pdb_00006gko; pdb_00006gyj; pdb_00006n1s; pdb_00006n1t; pdb_00006nnr; pdb_00006oju; pdb_00006ojv; pdb_00006pf3; pdb_00006pf4; pdb_00006pf5; 
				pdb_00006pf6; pdb_00006qxg; pdb_00006qxh; pdb_00006qxs; pdb_00006qya; pdb_00006qyq; pdb_00006r2e; pdb_00006y08; pdb_00006zxo; pdb_00007ctw; pdb_00007f3y; pdb_00007f3z; 
				pdb_00007fgw; pdb_00007fgx; pdb_00007fgy; pdb_00007jx1; pdb_00007jxf; pdb_00007ta9; pdb_00008dae; pdb_00008wgm
			
			

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