PROSITE logo

PROSITE entry PS00095


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] C5_MTASE_2
Accession [info] PS00095
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2003 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00089

Name and characterization of the entry

Description [info] C-5 cytosine-specific DNA methylases C-terminal signature.
Pattern [info] 
[RKQGTF]-x(2)-G-N-[SA]-[LIVF]-x-[VIP]-x-[LVMT]-x(3)-[LIVM]-x(3)-[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.


Total number of hits 78 in 78 different sequences
Number of true positive hits 68 in 68 different sequences
Number of 'unknown' hits 0
Number of false positive hits 10 in 10 different sequences
Number of false negative sequences 25
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 87.18 %
Recall (true positives / (true positives + false negatives)) 73.12 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 68 sequences 

CMT2_ORYSJ  (Q5KQL9), DCM_ECO57   (P0AEE0), DCM_ECOLI   (P0AED9), 

DNM1A_ORYSJ (Q7Y1I7), DNM1B_ORYSJ (B1Q3J6), DNMT1_ARATH (P34881), 
DNMT1_BOVIN (Q24K09), DNMT1_CHICK (Q92072), DNMT1_HUMAN (P26358), 
DNMT1_MOUSE (P13864), DNMT1_PARLI (Q27746), DNMT1_RAT   (Q9Z330), 
DNMT2_ARATH (Q9M0S8), DNMT3_ARATH (Q9T0I1), DNMT4_ARATH (O23273), 
MT36_OCEIH  (Q8EL95), MTA1_THAGE  (P94147), MTAB_PICP2  (P34883), 
MTB1_BACP9  (P0DW08), MTB1_BREEP  (P10283), MTB1_HERAU  (P25262), 
MTB1_LYSSH  (P13906), MTB6_BACSF  (P43420), MTBA_ANEAE  (P19888), 
MTBB_BPSPB  (P09389), MTBF_BACIU  (P17044), MTBP_BACSU  (P68585), 
MTBP_BPPHT  (P68586), MTBR_BACIU  (P06530), MTBR_BPRH1  (P09915), 
MTBS_BPSPR  (P00476), MTC1_HERAU  (P25263), MTC2_HERAU  (P25264), 
MTD1_DESNO  (P05302), MTD1_HERAU  (P24600), MTD2_HERAU  (P25265), 
MTD5_DACSA  (P50185), MTE1_HERAU  (P25266), MTE2_ECOLX  (P05101), 
MTE8_ECOLX  (P50196), MTF1_FUSNU  (P34906), MTH1_HAEPH  (P05102), 
MTH2_HAEAE  (O30868), MTH3_HAEAE  (P20589), MTH5_HAEIN  (P45000), 
MTHA_HAEPH  (P50192), MTHT_METTF  (P29567), MTM1_MORSP  (P11408), 
MTM4_NEIGO  (P31033), MTN1_LENAE  (P50188), MTNX_NEILA  (P24581), 
MTP1_PSYTA  (O33481), MTP2_NEIGO  (P08455), MTS1_SALIN  (P09795), 
MTS2_SHISO  (P34879), MTS3_STAAU  (P16668), MTS9_STAAU  (P23737), 
MTSA_LACLC  (P34877), MTSB_LACLC  (P34878), MTSI_SPISQ  (P15840), 
MTX2_XANOR  (P52311), PMT1M_SCHPO (P40999), TRDMT_BOVIN (Q7YS61), 
TRDMT_HUMAN (O14717), TRDMT_MOUSE (O55055), TRDMT_RAT   (Q4G073), 
TRDMT_SPOFR (A0A2H1VE33), YDIP_BACSU  (O34680)
» more

UniProtKB/Swiss-Prot
False negative sequences		 25 sequences 

CMT1_ORYSJ  (A0A0P0VUY4), CMT3_ORYSJ  (C0SQ89), DNM3A_CHICK (Q4W5Z4), 

DNM3A_HUMAN (Q9Y6K1), DNM3A_MOUSE (O88508), DNM3A_RAT   (Q1LZ53), 
DNM3B_HUMAN (Q9UBC3), DNM3B_MOUSE (O88509), DRM1L_ARATH (Q9LXE5), 
DRM2_ARATH  (Q9M548), MT51_METJA  (Q57983), MTA1_CELCE  (P31974), 
MTAP_ARTPN  (D4ZX35), MTB1_BREBE  (P34905), MTB1_NEIGO  (Q59603), 
MTB5_NEIGO  (Q59605), MTC1_PBCVI  (P36216), MTD1_NEIMC  (Q9RLM4), 
MTF7_NEIGO  (Q59606), MTG1_AVIVO  (P25282), MTG2_AVIVO  (P25283), 
MTH2_HAEPA  (P15446), MTM7_METJA  (Q58600), MTN4_NEILA  (P50182), 
YDIO_BACSU  (O34939)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

MTG1_HERAU  (P25267)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			10 sequences
			


			
ATPB_MYCGI  (A4T8K2), ATPB_MYCLE  (P45823), CDAA_BACSU  (Q45589), 

			
GCY8E_DROME (Q8INF0), OBG_BORAP   (Q0SM73), OBG_BORBU   (O51722), 
OBG_BORBZ   (B7J0M7), OBG_BORGP   (Q65ZZ3), WCAF_ECOLI  (P0ACD2), 
WCAF_SHIFL  (P0ACD3)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			61 PDB
			


			10MH; 1DCT; 1FJX; 1G55; 1HMY; 1M0E; 1MHT; 1SKM; 1SVU; 2C7O; 2C7P; 2C7Q; 
			
				2C7R; 2HMY; 2HR1; 2I9K; 2UYC; 2UYH; 2UZ4; 2Z6A; 2Z6Q; 2Z6U; 2ZCJ; 3AV4; 
				3AV5; 3AV6; 3EEO; 3MHT; 3PT6; 3PT9; 3PTA; 3SWR; 3UBT; 4DA4; 4H0N; 4MHT; 
				4WXX; 4YOC; 5CIY; 5GUT; 5GUV; 5LOD; 5MHT; 5WY1; 6FDF; 6MHT; 6W8V; 6W8W; 
				6X9I; 6X9J; 6X9K; 7MHT; 7SFC; 7SFD; 7SFE; 7SFF; 7SFG; 7XI9; 7XIB; 8MHT; 
				9MHT
			
			

			» more