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PROSITE entry PS00116


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00116
Entry name [info] DNA_POLYMERASE_B
Accession [info] PS00116
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00107

Name and characterization of the entry

Description [info] DNA polymerase family B signature.
Pattern [info] 
[YA]-[GLIVMSTAC]-D-T-D-[SG]-[LIVMFTC]-{LA}-[LIVMSTAC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 165 in 165 different sequences
Number of true positive hits 148 in 148 different sequences
Number of 'unknown' hits 2 in 2 different sequences
Number of false positive hits 15 in 15 different sequences
Number of false negative sequences 26
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 90.80 %
Recall (true positives / (true positives + false negatives)) 85.06 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 148 sequences 

DPO1_KLULA  (P09804), DPO2_ECOLI  (P21189), DPO2_KLULA  (P05468), 

DPO5_SCHPO  (O60094), DPO5_YEAST  (P39985), DPOD1_ARATH (Q9LVN7), 
DPOD1_BOVIN (P28339), DPOD1_CAEEL (P90829), DPOD1_DICDI (Q54N97), 
DPOD1_DROME (P54358), DPOD1_HUMAN (P28340), DPOD1_MESAU (P97283), 
DPOD1_MOUSE (P52431), DPOD1_ORYSJ (Q9LRE6), DPOD1_RAT   (O54747), 
DPOD1_SOYBN (O48901), DPOD_CANAX  (P46588), DPOD_PLAFK  (P30315), 
DPOD_SCHPO  (P30316), DPOD_YEAST  (P15436), DPOL1_AERPE (O93745), 
DPOL1_METTH (O27276), DPOL1_SACS2 (P26811), DPOL1_SULAC (P95690), 
DPOL1_SULOH (O50607), DPOL2_AERPE (O93746), DPOLA_ARATH (Q9FHA3), 
DPOLA_DICDI (Q54SV8), DPOLA_DROME (P26019), DPOLA_HUMAN (P09884), 
DPOLA_LEIDO (O00874), DPOLA_MOUSE (P33609), DPOLA_ORYSJ (O48653), 
DPOLA_OXYTR (Q27152), DPOLA_RAT   (O89042), DPOLA_SCHPO (P28040), 
DPOLA_STENO (Q94636), DPOLA_TRYBB (P27727), DPOLA_XENLA (Q9DE46), 
DPOLA_YEAST (P13382), DPOL_ADE02  (P03261), DPOL_ADE04  (P87503), 
DPOL_ADE05  (P04495), DPOL_ADE07  (P05664), DPOL_ADE12  (P06538), 
DPOL_ADE40  (P48311), DPOL_ADEB2  (O72539), DPOL_ADEB3  (O72540), 
DPOL_ADECC  (Q65946), DPOL_ADECT  (P87553), DPOL_ADEG1  (Q64751), 
DPOL_ADES1  (Q8QNT0), DPOL_ADET1  (Q88469), DPOL_ALHV1  (O36363), 
DPOL_ARCFU  (O29753), DPOL_ASFB7  (P42489), DPOL_ASFK5  (P0C974), 
DPOL_ASFL6  (P43139), DPOL_ASFM2  (P0C972), DPOL_ASFP4  (P0C971), 
DPOL_ASFWA  (P0C973), DPOL_BPB03  (Q37882), DPOL_BPCP1  (Q37989), 
DPOL_BPKVM  (Q6WI70), DPOL_BPM2   (P19894), DPOL_BPNF   (B7SSM2), 
DPOL_BPPH2  (P03680), DPOL_BPPRD  (P10479), DPOL_BPPZA  (P06950), 
DPOL_BPR69  (Q38087), DPOL_BPT4   (P04415), DPOL_CBEPV  (P30319), 
DPOL_DESST  (Q7SIG7), DPOL_EBVA8  (Q1HVC1), DPOL_EBVB9  (P03198), 
DPOL_EBVG   (Q3KSP1), DPOL_EHV1B  (P28858), DPOL_EHV1V  (Q6S6P1), 
DPOL_EHV2   (P52367), DPOL_ELHVK  (Q9DKT8), DPOL_FOWPN  (P21402), 
DPOL_GAHVM  (Q9E6N9), DPOL_GPCMV  (Q69025), DPOL_HCMVA  (P08546), 
DPOL_HCMVM  (Q6SW77), DPOL_HHV11  (P04293), DPOL_HHV1A  (P07917), 
DPOL_HHV1K  (P04292), DPOL_HHV1S  (P09854), DPOL_HHV21  (P07918), 
DPOL_HHV2H  (P89453), DPOL_HHV6U  (P28857), DPOL_HHV6Z  (Q9QJ32), 
DPOL_HHV7J  (P52342), DPOL_HHV8P  (Q2HRD0), DPOL_HVAVE  (A4KX57), 
DPOL_ICHVA  (P28859), DPOL_METJA  (Q58295), DPOL_METVO  (P52025), 
DPOL_MONPV  (A0A7H0DN44), DPOL_MUHVS  (P27172), DPOL_NPVAC  (P18131), 
DPOL_NPVBM  (P41712), DPOL_NPVCF  (Q90162), DPOL_NPVLD  (P30318), 
DPOL_NPVOP  (Q83948), DPOL_ORFN2  (Q84173), DPOL_PBCV1  (P30321), 
DPOL_PBCVN  (P30320), DPOL_POV01  (A7U6F2), DPOL_PSHV1  (Q6UDK1), 
DPOL_PYRAB  (P0CL77), DPOL_PYRAY  (P0CL76), DPOL_PYRFU  (P61875), 
DPOL_PYRGL  (Q9HH06), DPOL_PYRHO  (O59610), DPOL_PYRSD  (Q51334), 
DPOL_PYRWO  (P61876), DPOL_RCMVM  (Q85428), DPOL_RHCM6  (O71121), 
DPOL_RSIV   (O70736), DPOL_SFAVA  (Q779J8), DPOL_SHV21  (P24907), 
DPOL_THEGO  (P56689), DPOL_THEKO  (P77933), DPOL_THES9  (Q56366), 
DPOL_TNAVC  (Q4U3V0), DPOL_TUHV1  (Q9YUS3), DPOL_TUHV2  (Q9YUS2), 
DPOL_VACCA  (O57191), DPOL_VACCC  (P20509), DPOL_VACCW  (P06856), 
DPOL_VAR67  (P0DOO5), DPOL_VARV   (P0DOO6), DPOL_VZVD   (P09252), 
DPOL_VZVO   (Q4JQU7), DPOM_ASCIM  (P22374), DPOM_CLAPU  (P22373), 
DPOM_MAIZE  (P10582), DPOM_NEUCS  (P33537), DPOM_NEUIN  (P33538), 
DPOM_PODAS  (Q01529), DPOZ_DROME  (Q9GSR1), DPOZ_SCHPO  (Q9P6L6), 
DPOZ_YEAST  (P14284), REV3L_HUMAN (O60673), REV3L_MOUSE (Q61493), 
REV3_ARATH  (Q766Z3)
» more

UniProtKB/Swiss-Prot
False negative sequences		 26 sequences 

DPOE_ASPFU  (Q4WXH8), DPOE_CANGA  (Q6FNY7), DPOE_CRYNB  (P0CN27), 

DPOE_CRYNJ  (P0CN26), DPOE_DEBHA  (Q6BNG2), DPOE_EMENI  (O93845), 
DPOE_EREGS  (Q752B8), DPOE_KLULA  (Q6CUS7), DPOE_MYCMD  (Q4PFV5), 
DPOE_SCHPO  (P87154), DPOE_YARLI  (Q6C4J0), DPOE_YEAST  (P21951), 
DPOL2_SACS2 (Q07635), DPOL3_SACS2 (P95979), DPOL3_SACSH (O05706), 
DPOL_ABVP   (A4ZU91), DPOL_HIS1I  (Q25BI3), DPOL_IIV3   (Q196U0), 
DPOL_IIV6   (Q9QSK2), DPOL_OSHVF  (Q6R7C9), DPOL_THEAG  (O33845), 
DPOL_THEFM  (P74918), DPOL_THEG8  (Q9HH84), DPOL_THEHY  (Q9HH05), 
DPOL_THELI  (P30317), DPOM_AGABT  (P30322)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 2 sequences 

LTP_VZVD(P09278), LTP_VZVO(Q4JQX9)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			15 sequences
			


			
ACDG1_METTE (Q50539), ACDG2_METTE (Q9C4Z0), ACDG_METAC  (Q8TH44), 

			
ATK_DROME   (Q9VPF0), C99L2_MOUSE (Q8BIF0), E2AK4_HUMAN (Q9P2K8), 
EIF3B_BOMMO (Q1HDZ5), FLUC2_LEIXX (Q6AHI4), PSTB1_VIBCH (Q9KU04), 
PSTB_HYDCU  (Q31I88), QWRF2_ARATH (Q94AI1), RBR3_CANAL  (Q5A5M7), 
SCO3_ARATH  (Q8GXD9), SYA_BRUA4   (A6X0E9), Y8444_DICDI (Q1ZXR0)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			268 PDB
			


			1CLQ; 1D5A; 1IG9; 1IH7; 1Q8I; 1Q9X; 1Q9Y; 1QHT; 1QQC; 1S5J; 1TGO; 1WAF; 
			
				1WAJ; 1WN7; 1WNS; 1XHX; 1XHZ; 1XI1; 2ATQ; 2DTU; 2DY4; 2EX3; 2GV9; 2JGU; 
				2OYQ; 2OZM; 2OZS; 2P5G; 2P5O; 2PY5; 2PYJ; 2PYL; 2PZS; 2VWJ; 2VWK; 2XHB; 
				3A2F; 3CFO; 3CFP; 3CFR; 3CQ8; 3IAY; 3K57; 3K58; 3K59; 3K5L; 3K5M; 3K5N; 
				3K5O; 3KD1; 3KD5; 3L8B; 3LDS; 3LZI; 3LZJ; 3MAQ; 3NAE; 3NCI; 3NDK; 3NE6; 
				3NGI; 3NHG; 3QEI; 3QEP; 3QER; 3QES; 3QET; 3QEV; 3QEW; 3QEX; 3QNN; 3QNO; 
				3RMA; 3RMB; 3RMC; 3RMD; 3RWU; 3S9H; 3SCX; 3SI6; 3SJJ; 3SNN; 3SPY; 3SPZ; 
				3SQ0; 3SQ1; 3SQ2; 3SQ4; 3SUN; 3SUO; 3SUP; 3SUQ; 3TAB; 3TAE; 3TAF; 3TAG; 
				3UIQ; 4AHC; 4AIL; 4B08; 4DTJ; 4DTM; 4DTN; 4DTO; 4DTP; 4DTR; 4DTS; 4DTU; 
				4DTX; 4DU1; 4DU3; 4DU4; 4E3S; 4FJ5; 4FJ7; 4FJ8; 4FJ9; 4FJG; 4FJH; 4FJI; 
				4FJJ; 4FJK; 4FJL; 4FJM; 4FJN; 4FJX; 4FK0; 4FK2; 4FK4; 4FLT; 4FLU; 4FLV; 
				4FLW; 4FLX; 4FLY; 4FLZ; 4FM0; 4FM1; 4FM2; 4FVM; 4FXD; 4I9L; 4I9Q; 4J2A; 
				4J2B; 4J2D; 4J2E; 4K8X; 4K8Z; 4KHN; 4KHQ; 4KHS; 4KHU; 4KHW; 4KHY; 4KI4; 
				4KI6; 4M3R; 4M3T; 4M3U; 4M3W; 4M3X; 4M3Y; 4M3Z; 4M41; 4M42; 4M45; 4Q5V; 
				4QCL; 5EXR; 5H12; 5IUD; 5N2E; 5N2G; 5N2H; 5OMF; 5OMQ; 5OMV; 6AS7; 6IS7; 
				6ISF; 6ISG; 6ISH; 6ISI; 6P1H; 6Q4T; 6S1M; 6S1N; 6S1O; 6TNY; 6TNZ; 6V8P; 
				6V93; 7B06; 7B07; 7B08; 7B0F; 7B0G; 7B0H; 7F4Y; 7KC0; 7LUF; 7LXD; 7N2M; 
				7OM3; 7OMB; 7OMG; 7OPL; 7RSU; 7S0T; 7U5C; 8B9A; 8B9B; 8B9C; 8B9D; 8D0B; 
				8D0K; 8D96; 8D9D; 8FOC; 8FOD; 8FOE; 8FOH; 8FOJ; 8FOK; 8G99; 8G9F; 8G9L; 
				8G9N; 8G9O; 8HDZ; 8HG1; 8HLZ; 8HM0; 8HOY; 8HPA; 8J86; 8K8S; 8K8U; 8OJ6; 
				8OJ7; 8OJA; 8OJB; 8OJC; 8OJD; 8Q3R; 8QJ7; 8TLQ; 8TLT; 8UCU; 8UCV; 8UCW; 
				8V5M; 8V5N; 8V5O; 8V6G; 8V6H; 8V6I; 8V6J; 8VY3; 8WPE; 8WPF; 8WPK; 8WPP; 
				9C8V; 9ENP; 9ENQ; 9GP8
			
			

			» more