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PROSITE entry PS00116


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PURL: https://purl.expasy.org/prosite/signature/PS00116

Direct ScanProsite submission
General information about the entry

Entry name [info] DNA_POLYMERASE_B
Accession [info] PS00116
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00107

Name and characterization of the entry

Description [info] DNA polymerase family B signature.
Pattern [info] 
[YA]-[GLIVMSTAC]-D-T-D-[SG]-[LIVMFTC]-{LA}-[LIVMSTAC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 165 in 165 different sequences
Number of true positive hits 148 in 148 different sequences
Number of 'unknown' hits 2 in 2 different sequences
Number of false positive hits 15 in 15 different sequences
Number of false negative sequences 26
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 90.80 %
Recall (true positives / (true positives + false negatives)) 85.06 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 148 sequences 

DPO1_KLULA  (P09804), DPO2_ECOLI  (P21189), DPO2_KLULA  (P05468), 

DPO5_SCHPO  (O60094), DPO5_YEAST  (P39985), DPOD1_ARATH (Q9LVN7), 
DPOD1_BOVIN (P28339), DPOD1_CAEEL (P90829), DPOD1_DICDI (Q54N97), 
DPOD1_DROME (P54358), DPOD1_HUMAN (P28340), DPOD1_MESAU (P97283), 
DPOD1_MOUSE (P52431), DPOD1_ORYSJ (Q9LRE6), DPOD1_RAT   (O54747), 
DPOD1_SOYBN (O48901), DPOD_CANAX  (P46588), DPOD_PLAFK  (P30315), 
DPOD_SCHPO  (P30316), DPOD_YEAST  (P15436), DPOL1_AERPE (O93745), 
DPOL1_METTH (O27276), DPOL1_SACS2 (P26811), DPOL1_SULAC (P95690), 
DPOL1_SULOH (O50607), DPOL2_AERPE (O93746), DPOLA_ARATH (Q9FHA3), 
DPOLA_DICDI (Q54SV8), DPOLA_DROME (P26019), DPOLA_HUMAN (P09884), 
DPOLA_LEIDO (O00874), DPOLA_MOUSE (P33609), DPOLA_ORYSJ (O48653), 
DPOLA_OXYTR (Q27152), DPOLA_RAT   (O89042), DPOLA_SCHPO (P28040), 
DPOLA_STENO (Q94636), DPOLA_TRYBB (P27727), DPOLA_XENLA (Q9DE46), 
DPOLA_YEAST (P13382), DPOL_ADE02  (P03261), DPOL_ADE04  (P87503), 
DPOL_ADE05  (P04495), DPOL_ADE07  (P05664), DPOL_ADE12  (P06538), 
DPOL_ADE40  (P48311), DPOL_ADEB2  (O72539), DPOL_ADEB3  (O72540), 
DPOL_ADECC  (Q65946), DPOL_ADECT  (P87553), DPOL_ADEG1  (Q64751), 
DPOL_ADES1  (Q8QNT0), DPOL_ADET1  (Q88469), DPOL_ALHV1  (O36363), 
DPOL_ARCFU  (O29753), DPOL_ASFB7  (P42489), DPOL_ASFK5  (P0C974), 
DPOL_ASFL6  (P43139), DPOL_ASFM2  (P0C972), DPOL_ASFP4  (P0C971), 
DPOL_ASFWA  (P0C973), DPOL_BPB03  (Q37882), DPOL_BPCP1  (Q37989), 
DPOL_BPKVM  (Q6WI70), DPOL_BPM2   (P19894), DPOL_BPNF   (B7SSM2), 
DPOL_BPPH2  (P03680), DPOL_BPPRD  (P10479), DPOL_BPPZA  (P06950), 
DPOL_BPR69  (Q38087), DPOL_BPT4   (P04415), DPOL_CBEPV  (P30319), 
DPOL_DESST  (Q7SIG7), DPOL_EBVA8  (Q1HVC1), DPOL_EBVB9  (P03198), 
DPOL_EBVG   (Q3KSP1), DPOL_EHV1B  (P28858), DPOL_EHV1V  (Q6S6P1), 
DPOL_EHV2   (P52367), DPOL_ELHVK  (Q9DKT8), DPOL_FOWPN  (P21402), 
DPOL_GAHVM  (Q9E6N9), DPOL_GPCMV  (Q69025), DPOL_HCMVA  (P08546), 
DPOL_HCMVM  (Q6SW77), DPOL_HHV11  (P04293), DPOL_HHV1A  (P07917), 
DPOL_HHV1K  (P04292), DPOL_HHV1S  (P09854), DPOL_HHV21  (P07918), 
DPOL_HHV2H  (P89453), DPOL_HHV6U  (P28857), DPOL_HHV6Z  (Q9QJ32), 
DPOL_HHV7J  (P52342), DPOL_HHV8P  (Q2HRD0), DPOL_HVAVE  (A4KX57), 
DPOL_ICHVA  (P28859), DPOL_METJA  (Q58295), DPOL_METVO  (P52025), 
DPOL_MONPV  (A0A7H0DN44), DPOL_MUHVS  (P27172), DPOL_NPVAC  (P18131), 
DPOL_NPVBM  (P41712), DPOL_NPVCF  (Q90162), DPOL_NPVLD  (P30318), 
DPOL_NPVOP  (Q83948), DPOL_ORFN2  (Q84173), DPOL_PBCV1  (P30321), 
DPOL_PBCVN  (P30320), DPOL_POV01  (A7U6F2), DPOL_PSHV1  (Q6UDK1), 
DPOL_PYRAB  (P0CL77), DPOL_PYRAY  (P0CL76), DPOL_PYRFU  (P61875), 
DPOL_PYRGL  (Q9HH06), DPOL_PYRHO  (O59610), DPOL_PYRSD  (Q51334), 
DPOL_PYRWO  (P61876), DPOL_RCMVM  (Q85428), DPOL_RHCM6  (O71121), 
DPOL_RSIV   (O70736), DPOL_SFAVA  (Q779J8), DPOL_SHV21  (P24907), 
DPOL_THEGO  (P56689), DPOL_THEKO  (P77933), DPOL_THES9  (Q56366), 
DPOL_TNAVC  (Q4U3V0), DPOL_TUHV1  (Q9YUS3), DPOL_TUHV2  (Q9YUS2), 
DPOL_VACCA  (O57191), DPOL_VACCC  (P20509), DPOL_VACCW  (P06856), 
DPOL_VAR67  (P0DOO5), DPOL_VARV   (P0DOO6), DPOL_VZVD   (P09252), 
DPOL_VZVO   (Q4JQU7), DPOM_ASCIM  (P22374), DPOM_CLAPU  (P22373), 
DPOM_MAIZE  (P10582), DPOM_NEUCS  (P33537), DPOM_NEUIN  (P33538), 
DPOM_PODAS  (Q01529), DPOZ_DROME  (Q9GSR1), DPOZ_SCHPO  (Q9P6L6), 
DPOZ_YEAST  (P14284), REV3L_HUMAN (O60673), REV3L_MOUSE (Q61493), 
REV3_ARATH  (Q766Z3)
» more

UniProtKB/Swiss-Prot
False negative sequences		 26 sequences 

DPOE_ASPFU  (Q4WXH8), DPOE_CANGA  (Q6FNY7), DPOE_CRYNB  (P0CN27), 

DPOE_CRYNJ  (P0CN26), DPOE_DEBHA  (Q6BNG2), DPOE_EMENI  (O93845), 
DPOE_EREGS  (Q752B8), DPOE_KLULA  (Q6CUS7), DPOE_MYCMD  (Q4PFV5), 
DPOE_SCHPO  (P87154), DPOE_YARLI  (Q6C4J0), DPOE_YEAST  (P21951), 
DPOL2_SACS2 (Q07635), DPOL3_SACS2 (P95979), DPOL3_SACSH (O05706), 
DPOL_ABVP   (A4ZU91), DPOL_HIS1I  (Q25BI3), DPOL_IIV3   (Q196U0), 
DPOL_IIV6   (Q9QSK2), DPOL_OSHVF  (Q6R7C9), DPOL_THEAG  (O33845), 
DPOL_THEFM  (P74918), DPOL_THEG8  (Q9HH84), DPOL_THEHY  (Q9HH05), 
DPOL_THELI  (P30317), DPOM_AGABT  (P30322)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 2 sequences 

LTP_VZVD(P09278), LTP_VZVO(Q4JQX9)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			15 sequences
			


			
ACDG1_METTE (Q50539), ACDG2_METTE (Q9C4Z0), ACDG_METAC  (Q8TH44), 

			
ATK_DROME   (Q9VPF0), C99L2_MOUSE (Q8BIF0), E2AK4_HUMAN (Q9P2K8), 
EIF3B_BOMMO (Q1HDZ5), FLUC2_LEIXX (Q6AHI4), PSTB1_VIBCH (Q9KU04), 
PSTB_HYDCU  (Q31I88), QWRF2_ARATH (Q94AI1), RBR3_CANAL  (Q5A5M7), 
SCO3_ARATH  (Q8GXD9), SYA_BRUA4   (A6X0E9), Y8444_DICDI (Q1ZXR0)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			278 PDB
			


			pdb_00001clq; pdb_00001d5a; pdb_00001ig9; pdb_00001ih7; pdb_00001q8i; pdb_00001q9x; pdb_00001q9y; pdb_00001qht; pdb_00001qqc; pdb_00001s5j; pdb_00001tgo; pdb_00001waf; 
			
				pdb_00001waj; pdb_00001wn7; pdb_00001wns; pdb_00001xhx; pdb_00001xhz; pdb_00001xi1; pdb_00002atq; pdb_00002dtu; pdb_00002dy4; pdb_00002ex3; pdb_00002gv9; pdb_00002jgu; 
				pdb_00002oyq; pdb_00002ozm; pdb_00002ozs; pdb_00002p5g; pdb_00002p5o; pdb_00002py5; pdb_00002pyj; pdb_00002pyl; pdb_00002pzs; pdb_00002vwj; pdb_00002vwk; pdb_00002xhb; 
				pdb_00003a2f; pdb_00003cfo; pdb_00003cfp; pdb_00003cfr; pdb_00003cq8; pdb_00003iay; pdb_00003k57; pdb_00003k58; pdb_00003k59; pdb_00003k5l; pdb_00003k5m; pdb_00003k5n; 
				pdb_00003k5o; pdb_00003kd1; pdb_00003kd5; pdb_00003l8b; pdb_00003lds; pdb_00003lzi; pdb_00003lzj; pdb_00003maq; pdb_00003nae; pdb_00003nci; pdb_00003ndk; pdb_00003ne6; 
				pdb_00003ngi; pdb_00003nhg; pdb_00003qei; pdb_00003qep; pdb_00003qer; pdb_00003qes; pdb_00003qet; pdb_00003qev; pdb_00003qew; pdb_00003qex; pdb_00003qnn; pdb_00003qno; 
				pdb_00003rma; pdb_00003rmb; pdb_00003rmc; pdb_00003rmd; pdb_00003rwu; pdb_00003s9h; pdb_00003scx; pdb_00003si6; pdb_00003sjj; pdb_00003snn; pdb_00003spy; pdb_00003spz; 
				pdb_00003sq0; pdb_00003sq1; pdb_00003sq2; pdb_00003sq4; pdb_00003sun; pdb_00003suo; pdb_00003sup; pdb_00003suq; pdb_00003tab; pdb_00003tae; pdb_00003taf; pdb_00003tag; 
				pdb_00003uiq; pdb_00004ahc; pdb_00004ail; pdb_00004b08; pdb_00004dtj; pdb_00004dtm; pdb_00004dtn; pdb_00004dto; pdb_00004dtp; pdb_00004dtr; pdb_00004dts; pdb_00004dtu; 
				pdb_00004dtx; pdb_00004du1; pdb_00004du3; pdb_00004du4; pdb_00004e3s; pdb_00004fj5; pdb_00004fj7; pdb_00004fj8; pdb_00004fj9; pdb_00004fjg; pdb_00004fjh; pdb_00004fji; 
				pdb_00004fjj; pdb_00004fjk; pdb_00004fjl; pdb_00004fjm; pdb_00004fjn; pdb_00004fjx; pdb_00004fk0; pdb_00004fk2; pdb_00004fk4; pdb_00004flt; pdb_00004flu; pdb_00004flv; 
				pdb_00004flw; pdb_00004flx; pdb_00004fly; pdb_00004flz; pdb_00004fm0; pdb_00004fm1; pdb_00004fm2; pdb_00004fvm; pdb_00004fxd; pdb_00004i9l; pdb_00004i9q; pdb_00004j2a; 
				pdb_00004j2b; pdb_00004j2d; pdb_00004j2e; pdb_00004k8x; pdb_00004k8z; pdb_00004khn; pdb_00004khq; pdb_00004khs; pdb_00004khu; pdb_00004khw; pdb_00004khy; pdb_00004ki4; 
				pdb_00004ki6; pdb_00004m3r; pdb_00004m3t; pdb_00004m3u; pdb_00004m3w; pdb_00004m3x; pdb_00004m3y; pdb_00004m3z; pdb_00004m41; pdb_00004m42; pdb_00004m45; pdb_00004q5v; 
				pdb_00004qcl; pdb_00005exr; pdb_00005h12; pdb_00005iud; pdb_00005n2e; pdb_00005n2g; pdb_00005n2h; pdb_00005omf; pdb_00005omq; pdb_00005omv; pdb_00006as7; pdb_00006is7; 
				pdb_00006isf; pdb_00006isg; pdb_00006ish; pdb_00006isi; pdb_00006p1h; pdb_00006q4t; pdb_00006s1m; pdb_00006s1n; pdb_00006s1o; pdb_00006tny; pdb_00006tnz; pdb_00006v8p; 
				pdb_00006v93; pdb_00007b06; pdb_00007b07; pdb_00007b08; pdb_00007b0f; pdb_00007b0g; pdb_00007b0h; pdb_00007f4y; pdb_00007kc0; pdb_00007luf; pdb_00007lxd; pdb_00007n2m; 
				pdb_00007om3; pdb_00007omb; pdb_00007omg; pdb_00007opl; pdb_00007rsu; pdb_00007s0t; pdb_00007u5c; pdb_00008b9a; pdb_00008b9b; pdb_00008b9c; pdb_00008b9d; pdb_00008d0b; 
				pdb_00008d0k; pdb_00008d96; pdb_00008d9d; pdb_00008foc; pdb_00008fod; pdb_00008foe; pdb_00008foh; pdb_00008foj; pdb_00008fok; pdb_00008g99; pdb_00008g9f; pdb_00008g9l; 
				pdb_00008g9n; pdb_00008g9o; pdb_00008hdz; pdb_00008hg1; pdb_00008hlz; pdb_00008hm0; pdb_00008hoy; pdb_00008hpa; pdb_00008j86; pdb_00008k8s; pdb_00008k8u; pdb_00008oj6; 
				pdb_00008oj7; pdb_00008oja; pdb_00008ojb; pdb_00008ojc; pdb_00008ojd; pdb_00008q3r; pdb_00008qj7; pdb_00008tlq; pdb_00008tlt; pdb_00008ucu; pdb_00008ucv; pdb_00008ucw; 
				pdb_00008v5m; pdb_00008v5n; pdb_00008v5o; pdb_00008v6g; pdb_00008v6h; pdb_00008v6i; pdb_00008v6j; pdb_00008vy3; pdb_00008wpe; pdb_00008wpf; pdb_00008wpk; pdb_00008wpp; 
				pdb_00008ywg; pdb_00008ywi; pdb_00008ywm; pdb_00009c8v; pdb_00009ekb; pdb_00009enp; pdb_00009enq; pdb_00009gp8; pdb_00009k9r; pdb_00009k9s; pdb_00009k9t; pdb_00009k9u; 
				pdb_00009k9v; pdb_00009mj5
			
			

			» more