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Entry: PS00122

General information about the entry

Entry name [info] CARBOXYLESTERASE_B_1
Accession [info] PS00122
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1995 DATA UPDATE;
18-SEP-2019 INFO UPDATE.
PROSITE Doc. [info] PDOC00112
Associated ProRule [info] PRU10039

Name and characterization of the entry

Description [info] Carboxylesterases type-B serine active site.
Pattern [info]
F-[GR]-G-x(4)-[LIVM]-x-[LIV]-x-G-x-S-[STAG]-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2019_08 which contains 560'823 sequence entries.


Total number of hits 120 in 120 different sequences
Number of true positive hits 118 in 118 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 4
Number of 'partial' sequences 14
Precision (true positives / (true positives + false positives)) 98.33 %
Recall (true positives / (true positives + false negatives)) 96.72 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 11
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
118 sequences

ACE1_CAEBR  (Q27459    ), ACE1_CAEEL  (P38433    ), ACE4_CAEBR  (Q9NDG8    ), 
ACES_ANOGA  (Q869C3    ), ACES_ANOST  (P56161    ), ACES_BOVIN  (P23795    ), 
ACES_BUNFA  (Q92035    ), ACES_CHICK  (P36196    ), ACES_CULPI  (Q86GC8    ), 
ACES_DANRE  (Q9DDE3    ), ACES_DROME  (P07140    ), ACES_ELEEL  (O42275    ), 
ACES_FELCA  (O62763    ), ACES_HUMAN  (P22303    ), ACES_LEPDE  (Q27677    ), 
ACES_MOUSE  (P21836    ), ACES_MYXGL  (Q92081    ), ACES_RABIT  (Q29499    ), 
ACES_RAT    (P37136    ), ACES_TETCF  (P04058    ), ACES_TORMA  (P07692    ), 
AQDA2_RHOER (A0A0E4AET8), CEL_BOVIN   (P30122    ), CEL_HUMAN   (P19835    ), 
CEL_MOUSE   (Q64285    ), CEL_RAT     (P07882    ), CES1D_MOUSE (Q8VCT4    ), 
CES1D_RAT   (P16303    ), CES1F_MOUSE (Q91WU0    ), CHLE1_BRALA (Q95000    ), 
CHLE2_BRALA (Q95001    ), CHLE_BOVIN  (P32749    ), CHLE_CANLF  (P32750    ), 
CHLE_FELCA  (O62760    ), CHLE_HORSE  (P81908    ), CHLE_HUMAN  (P06276    ), 
CHLE_MACMU  (P32751    ), CHLE_MIMIV  (Q5UR02    ), CHLE_MOUSE  (Q03311    ), 
CHLE_PANTT  (O62761    ), CHLE_PIG    (P32752    ), CHLE_RABIT  (P21927    ), 
CHLE_SHEEP  (P32753    ), CRYS_DICDI  (P21837    ), D2_DICDI    (P18142    ), 
EST1C_MOUSE (P23953    ), EST1C_RAT   (P10959    ), EST1E_MOUSE (Q64176    ), 
EST1E_RAT   (Q63108    ), EST1_CAEBR  (Q04456    ), EST1_CAEEL  (Q04457    ), 
EST1_CULPI  (P16854    ), EST1_HUMAN  (P23141    ), EST1_MACFA  (O46421    ), 
EST1_MESAU  (Q64419    ), EST1_MOUSE  (Q8VCC2    ), EST1_PIG    (Q29550    ), 
EST1_RABIT  (P12337    ), EST1_THEFU  (P86325    ), EST1_THEFY  (Q47M62    ), 
EST2A_MOUSE (Q8QZR3    ), EST2C_MOUSE (Q91WG0    ), EST2E_MOUSE (Q8BK48    ), 
EST2_CAEEL  (Q07085    ), EST2_HUMAN  (O00748    ), EST2_RABIT  (P14943    ), 
EST3A_MOUSE (Q63880    ), EST3B_MOUSE (Q8VCU1    ), EST3_HUMAN  (Q6UWW8    ), 
EST3_PONAB  (Q5RCL7    ), EST4A_BOVIN (P0C6R3    ), EST4A_HUMAN (Q5XG92    ), 
EST4A_MOUSE (Q8R0W5    ), EST4_RAT    (Q64573    ), EST5A_CANLF (Q6AW47    ), 
EST5A_DROMI (O16168    ), EST5A_DROPE (O16173    ), EST5A_DROPS (P25727    ), 
EST5A_FELCA (Q8I034    ), EST5A_HUMAN (Q6NT32    ), EST5A_MOUSE (Q6AW46    ), 
EST5A_RAT   (Q5GRG2    ), EST5A_SHEEP (Q3T930    ), EST5B_DROMI (O16170    ), 
EST5B_DROPE (O16172    ), EST5B_DROPS (P25726    ), EST5C_DROMI (O16169    ), 
EST5C_DROPE (O16171    ), EST5C_DROPS (P25725    ), EST5_RAT    (Q63010    ), 
EST6_APIME  (B2D0J5    ), EST6_DROMA  (P47982    ), EST6_DROME  (P08171    ), 
EST6_DROSI  (Q08662    ), ESTE_MYZPE  (P35501    ), ESTF_MYZPE  (P35502    ), 
ESTJ_HELVI  (P12992    ), ESTP_DROME  (P18167    ), ESTS_DROVI  (Q05487    ), 
FUMD_SPHMC  (D2D3B6    ), LIP1_ARTBC  (D4ASH1    ), LIP1_DIURU  (P20261    ), 
LIP1_GEOCN  (P17573    ), LIP1_GEOFE  (P79066    ), LIP1_YARLI  (Q99156    ), 
LIP2_DIURU  (P32946    ), LIP2_GEOCN  (P22394    ), LIP3_ARTBC  (D4B1N9    ), 
LIP3_DIURU  (P32947    ), LIP3_YARLI  (Q96VC9    ), LIP4_DIURU  (P32948    ), 
LIP5_DIURU  (P32949    ), PATB_ASPCL  (A1CFK9    ), PATB_PENEN  (A0A075TXZ3), 
PCD_PSEOX   (Q01470    ), PNBA_BACSU  (P37967    ), SASB_ANAPL  (Q04791    ), 
YC7C_SCHPO  (O94493    )
» more

UniProtKB/Swiss-Prot
False negative sequences
4 sequences

ACES_TRILK  (W4VSJ0    ), CES1P_HUMAN (Q9UKY3    ), ESTE_HVAVE  (A4KX74    ), 
ESTE_SFAVA  (Q0E588    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
14 sequences

ACES_CULPP  (Q867X3    ), ACES_CULQU  (Q867X2    ), ACES_CULTO  (Q86GC9    ), 
ACES_NAJOX  (Q7LZG1    ), EST1_SCHGA  (P81429    ), EST2_CULPI  (P21370    ), 
EST4_DROMO  (P10094    ), EST5_DROMO  (P10095    ), ESTA_SCHGA  (P81012    ), 
ESTB_SCHGA  (P81011    ), ESTJ_MANSE  (P19985    ), JHEA_TRINI  (P30809    ), 
JHEB_TRINI  (P30810    ), PMCH_RAT    (P80250    )
» more

UniProtKB/Swiss-Prot
False positive sequences
2 sequences

ICME_ARATH  (Q94AS5    ), ICML2_ARATH (Q1PET6    )

		

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