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PROSITE entry PS00123


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General information about the entry

Entry name [info] ALKALINE_PHOSPHATASE
Accession [info] PS00123
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-OCT-1993 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00113
Associated ProRule [info] PRU10042

Name and characterization of the entry

Description [info] Alkaline phosphatase active site.
Pattern [info]
[IV]-x-D-S-[GAS]-[GASC]-[GAST]-[GA]-T.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 36 in 36 different sequences
Number of true positive hits 27 in 27 different sequences
Number of 'unknown' hits 0
Number of false positive hits 9 in 9 different sequences
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 75.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 4
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
27 sequences

APH4_DROME  (Q24238), PPB1_HUMAN  (P05187), PPB3_BACSU  (P19405), 
PPB4_BACSU  (P19406), PPBH_PSEAB  (Q02QC9), PPBH_PSEAE  (P35483), 
PPBI1_RAT   (P15693), PPBI2_RAT   (P51740), PPBI_BOVIN  (P19111), 
PPBI_HUMAN  (P09923), PPBI_MOUSE  (P24822), PPBN_HUMAN  (P10696), 
PPBN_MOUSE  (P24823), PPBT_BOVIN  (P09487), PPBT_CHICK  (Q92058), 
PPBT_FELCA  (Q29486), PPBT_HUMAN  (P05186), PPBT_MOUSE  (P09242), 
PPBT_RAT(P08289), PPB_BOMMO   (P29523), PPB_ECOLI   (P00634), 
PPB_ESCF3   (P21948), PPB_GADMO   (P83456), PPB_SCHPO   (O60109), 
PPB_SERMA   (P19147), PPB_YEAST   (P11491), STRK_STRGR  (P09401)
» more

UniProtKB/Swiss-Prot
False positive sequences
9 sequences

CIAO1_ASPCL (A1CQL6), FBID2_RHOJR (Q0RVJ9), INF2_HUMAN  (Q27J81), 
INF2_MOUSE  (Q0GNC1), RBP10_BOVIN (A3KMV8), RDUF2_ARATH (Q940T5), 
SLAP_CAUVC  (P35828), TRPC_BUCAP  (P42393), ZAP1_YEAST  (P47043)
» more

PDB
[Detailed view]
54 PDB

1AJA; 1AJB; 1AJC; 1AJD; 1ALH; 1ALI; 1ALJ; 1ALK; 1ANI; 1ANJ; 1B8J; 1ED8; 1ED9; 1EW2; 1EW8; 1EW9; 1HJK; 1HQA; 1KH4; 1KH5; 1KH7; 1KH9; 1KHJ; 1KHK; 1KHL; 1KHN; 1URA; 1URB; 1Y6V; 1Y7A; 1ZEB; 1ZED; 1ZEF; 2ANH; 2GLQ; 2MLY; 3BDF; 3BDG; 3BDH; 3CMR; 3DYC; 3MK0; 3MK1; 3MK2; 3TG0; 4KJD; 4KJG; 5C66; 5JTL; 5JTN; 6PSI; 7YIV; 7YIW; 7YIX
» more