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PROSITE entry PS00125


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PURL: https://purl.expasy.org/prosite/signature/PS00125

Direct ScanProsite submission
General information about the entry

Entry name [info] SER_THR_PHOSPHATASE
Accession [info] PS00125
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00115

Name and characterization of the entry

Description [info] Serine/threonine specific protein phosphatases signature.
Pattern [info] 
[LIVMN]-[KR]-G-N-H-E.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 217 in 217 different sequences
Number of true positive hits 207 in 207 different sequences
Number of 'unknown' hits 0
Number of false positive hits 10 in 10 different sequences
Number of false negative sequences 5
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 95.39 %
Recall (true positives / (true positives + false negatives)) 97.64 %

Comments [info]

Taxonomic range [info] Bacteriophages, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 207 sequences 

BSL1_ARATH  (Q8L7U5), BSL1_ORYSJ  (Q60EX6), BSL2_ARATH  (Q9SJF0), 

BSL2_ORYSJ  (Q2QM47), BSL3_ARATH  (Q9SHS7), BSU1_ARATH  (Q9LR78), 
FYPP1_ARATH (Q9SX52), FYPP3_ARATH (Q9LHE7), FYPP_PEA(Q8LSN3), 
GLC7A_CAEBR (Q61JR3), GLC7A_CAEEL (Q27497), GLC7B_CAEBR (Q627N3), 
GLC7B_CAEEL (P48727), GLC7C_CAEEL (O02658), GLC7D_CAEEL (P91420), 
PP11_ACEPE  (P48480), PP11_ARATH  (P30366), PP11_DROME  (P48461), 
PP11_SCHPO  (P13681), PP11_TOBAC  (O04856), PP11_TRYBB  (P23733), 
PP11_YEAST  (P20604), PP12_ACEPE  (P48481), PP12_ARATH  (P48482), 
PP12_DROME  (P12982), PP12_SCHPO  (P23880), PP12_TOBAC  (O04857), 
PP12_TRYBB  (P23734), PP12_YEAST  (P32598), PP13_ARATH  (P48483), 
PP13_DROME  (Q05547), PP13_TOBAC  (O04858), PP14_ARATH  (P48484), 
PP15_ARATH  (P48485), PP16_ARATH  (P48486), PP17_ARATH  (O82733), 
PP18_ARATH  (O82734), PP19_ARATH  (Q9M9W3), PP1A_BOVIN  (Q3T0E7), 
PP1A_CANLF  (Q8WMS6), PP1A_HUMAN  (P62136), PP1A_MOUSE  (P62137), 
PP1A_RABIT  (P62139), PP1A_RAT(P62138), PP1B_BOVIN  (Q3SWW9), 
PP1B_CANLF  (Q8MJ47), PP1B_CHICK  (P62207), PP1B_DROME  (P48462), 
PP1B_HUMAN  (P62140), PP1B_MOUSE  (P62141), PP1B_PIG(P61292), 
PP1B_PONAB  (Q5R740), PP1B_RABIT  (P62143), PP1B_RAT(P62142), 
PP1B_XENLA  (Q6GQL2), PP1B_XENTR  (Q5I085), PP1GA_XENLA (P36874), 
PP1GB_XENLA (Q7SZ10), PP1G_BOVIN  (P61287), PP1G_CANLF  (Q8MJ46), 
PP1G_HUMAN  (P36873), PP1G_MOUSE  (P63087), PP1G_RAT(P63088), 
PP1_BRANA   (P23777), PP1_BRAOL   (P48487), PP1_DICDI   (O15757), 
PP1_EMENI   (P20654), PP1_MAIZE   (P22198), PP1_MEDSV   (P48488), 
PP1_NEUCR   (Q9UW86), PP1_ORYSJ   (P48489), PP1_PHAVU   (P48490), 
PP2A1_ARATH (Q07099), PP2A1_EMENI (Q9HFQ2), PP2A1_NEUCR (P48580), 
PP2A1_ORYSI (A2YEB4), PP2A1_ORYSJ (Q0DBD3), PP2A1_PARTE (P48726), 
PP2A1_SCHPO (P23635), PP2A1_YEAST (P23594), PP2A2_ARATH (Q07098), 
PP2A2_BLUHO (Q8X178), PP2A2_ORYSI (A2XN40), PP2A2_ORYSJ (Q10BT5), 
PP2A2_PARTE (A0CNL9), PP2A2_SCHPO (P23636), PP2A2_YEAST (P23595), 
PP2A3_ARATH (Q07100), PP2A3_ORYSI (A2X2G3), PP2A3_ORYSJ (Q0E2S4), 
PP2A3_PARTE (Q6BFF6), PP2A4_ARATH (P48578), PP2A4_ORYSI (P0C5D7), 
PP2A4_ORYSJ (A3C4N5), PP2A4_YEAST (P32838), PP2A5_ARATH (O04951), 
PP2A5_TOBAC (O04860), PP2AA_BOVIN (P67774), PP2AA_CHICK (P48463), 
PP2AA_DICDI (Q9XZE5), PP2AA_HUMAN (P67775), PP2AA_MOUSE (P63330), 
PP2AA_PIG   (P67776), PP2AA_RABIT (P67777), PP2AA_RAT   (P63331), 
PP2AB_BOVIN (Q0P594), PP2AB_DICDI (Q54RD6), PP2AB_HUMAN (P62714), 
PP2AB_MOUSE (P62715), PP2AB_PIG   (P11493), PP2AB_RABIT (P11611), 
PP2AB_RAT   (P62716), PP2A_ACEPE  (P48577), PP2A_BRANA  (P23778), 
PP2A_CAEEL  (G5EGK8), PP2A_DROME  (P23696), PP2A_HELAN  (P48579), 
PP2A_HEVBR  (Q9ZSE4), PP2A_MEDSA  (Q06009), PP2A_TOBAC  (Q9XGH7), 
PP2B1_CRYNH (O42773), PP2B1_DROME (P48456), PP2B1_YEAST (P23287), 
PP2B2_DROME (Q27889), PP2B2_YEAST (P14747), PP2B3_DROME (Q9VXF1), 
PP2BA_BOVIN (P48452), PP2BA_DICDI (Q7YSW8), PP2BA_HUMAN (Q08209), 
PP2BA_MOUSE (P63328), PP2BA_RAT   (P63329), PP2BB_HUMAN (P16298), 
PP2BB_MOUSE (P48453), PP2BB_RAT   (P20651), PP2BC_HUMAN (P48454), 
PP2BC_MOUSE (P48455), PP2B_ASPFU  (Q4WUR1), PP2B_CAEEL  (Q0G819), 
PP2B_EMENI  (P48457), PP2B_NEUCR  (Q05681), PP2B_SCHPO  (Q12705), 
PP4C1_CAEBR (A8XE00), PP4C1_CAEEL (Q9XW79), PP4C2_CAEEL (Q9XTT8), 
PP4CA_DANRE (A8WGP3), PP4CB_DANRE (A9JRC7), PP4C_BOVIN  (A6H772), 
PP4C_CANGA  (Q6FM81), PP4C_DICDI  (Q9Y0B7), PP4C_DROME  (O76932), 
PP4C_EREGS  (Q74ZR2), PP4C_HUMAN  (P60510), PP4C_KLULA  (Q6CNT6), 
PP4C_MOUSE  (P97470), PP4C_PONAB  (Q5R6K8), PP4C_RABIT  (P11084), 
PP4C_RAT(Q5BJ92), PP4C_XENLA  (Q6IP91), PP4C_XENTR  (Q6P861), 
PP4C_YEAST  (P32345), PPE1_HUMAN  (O14829), PPE1_MOUSE  (O35655), 
PPE1_RAT(Q3SWT6), PPE1_SCHPO  (P36614), PPE2_HUMAN  (O14830), 
PPE2_MOUSE  (O35385), PPE_CAEEL   (G5EBX9), PPG1_CANAL  (Q5A6B6), 
PPIG_XENTR  (Q6NVU2), PPP5_ASPOR  (Q2U919), PPP5_HUMAN  (P53041), 
PPP5_MOUSE  (Q60676), PPP5_RAT(P53042), PPP5_SCHPO  (O43049), 
PPP5_YEAST  (P53043), PPP6_CAEEL  (Q09496), PPP6_DICDI  (Q9U9A3), 
PPP6_DROME  (Q27884), PPP6_HUMAN  (O00743), PPP6_MOUSE  (Q9CQR6), 
PPP6_RAT(Q64620), PPP7_ARATH  (Q9FN02), PPQ1_YEAST  (P32945), 
PPX1_ARATH  (P48529), PPX1_PARTE  (P49576), PPX2_ARATH  (P48528), 
PPX2_PARTE  (A0DJ90), PPX3_PARTE  (A0C1E4), PPX4_PARTE  (A0CCD2), 
PPY_DROME   (P11612), PPZ1_YEAST  (P26570), PPZ2_YEAST  (P33329), 
PPZA_ASPFC  (B0XUR7), PPZ_SCHPO   (P78968), PP_LAMBD(P03772), 
PRP1_ECOLI  (P55798), PRP1_SALTY  (Q8ZNY9), PRP2_ECOLI  (P55799), 
RDGC_DROME  (P40421), SIT4_CANAL  (Q59KY8), SITA_ASPFU  (Q4WM22), 
YD44_SCHPO  (Q10298), YL39_CAEEL  (P34430), YOU5_SCHPO  (O74789), 
YSD1_CAEEL  (P48459), YT91_CAEEL  (P48458), YY06_CAEEL  (P48460)
» more

UniProtKB/Swiss-Prot
False negative sequences		 5 sequences 

PPP5_ARATH  (Q84XU2), PPP5_SOLLC  (Q84K11), PPP7I_ARATH (Q9LEV0), 

PPP7L_ARATH (Q9LNG5), PRP2_SALTY  (Q8ZMH3)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

PPP5_RABIT  (P55739)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			10 sequences
			


			
ARSR2_HALSA (O52026), GFD1_YEAST  (Q04839), LAP1_CHAGB  (Q2H1T8), 

			
LAP1_NEUCR  (Q7RYC8), NFM_CHICK   (P16053), PYCC1_ECOLX (P0DV24), 
RPM1_CAEEL  (Q17551), SYP_SYNC1   (Q3A6R6), TASO2_MOUSE (Q5DTT3), 
XIRP2_MOUSE (Q4U4S6)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			151 PDB
			


			pdb_00001aui; pdb_00001fjm; pdb_00001g5b; pdb_00001it6; pdb_00001jk7; pdb_00001m63; pdb_00001mf8; pdb_00001s70; pdb_00001s95; pdb_00001tco; pdb_00001u32; pdb_00001wao; 
			
				pdb_00002bcd; pdb_00002bdx; pdb_00002iae; pdb_00002ie3; pdb_00002ie4; pdb_00002jog; pdb_00002npp; pdb_00002nyl; pdb_00002nym; pdb_00002o8a; pdb_00002o8g; pdb_00002p6b; 
				pdb_00003c5w; pdb_00003dw8; pdb_00003e7a; pdb_00003e7b; pdb_00003egg; pdb_00003egh; pdb_00003fga; pdb_00003h60; pdb_00003h61; pdb_00003h62; pdb_00003h63; pdb_00003h64; 
				pdb_00003h66; pdb_00003h67; pdb_00003h68; pdb_00003h69; pdb_00003hvq; pdb_00003icf; pdb_00003k7v; pdb_00003k7w; pdb_00003ll8; pdb_00003n5u; pdb_00003p71; pdb_00003v4y; 
				pdb_00004f0z; pdb_00004g9j; pdb_00004i5l; pdb_00004i5n; pdb_00004il1; pdb_00004iyp; pdb_00004ja7; pdb_00004ja9; pdb_00004lac; pdb_00004mov; pdb_00004moy; pdb_00004mp0; 
				pdb_00004or9; pdb_00004ora; pdb_00004orb; pdb_00004orc; pdb_00004ut2; pdb_00004ut3; pdb_00004v0u; pdb_00004v0v; pdb_00004v0w; pdb_00004v0x; pdb_00004xpn; pdb_00004zvz; 
				pdb_00004zx2; pdb_00005c1v; pdb_00005hpe; pdb_00005inb; pdb_00005ioh; pdb_00005j28; pdb_00005sve; pdb_00005ui1; pdb_00005w0w; pdb_00005wg8; pdb_00005zqv; pdb_00005zt0; 
				pdb_00006alz; pdb_00006czo; pdb_00006dcx; pdb_00006dno; pdb_00006g0i; pdb_00006g0j; pdb_00006ghm; pdb_00006nts; pdb_00006nuc; pdb_00006nuf; pdb_00006nuu; pdb_00006obn; 
				pdb_00006obp; pdb_00006obq; pdb_00006obr; pdb_00006obs; pdb_00006obu; pdb_00006tz7; pdb_00006tz8; pdb_00006uuq; pdb_00006zee; pdb_00006zef; pdb_00006zeg; pdb_00006zeh; 
				pdb_00006zei; pdb_00006zej; pdb_00006zk6; pdb_00007cun; pdb_00007k36; pdb_00007nzm; pdb_00007pks; pdb_00007qfb; pdb_00007qm2; pdb_00007qwj; pdb_00007sd0; pdb_00007soy; 
				pdb_00007t0y; pdb_00007tvf; pdb_00007txh; pdb_00007upi; pdb_00007ycx; pdb_00007zr5; pdb_00007zr6; pdb_00008a8f; pdb_00008b5r; pdb_00008dwk; pdb_00008dwl; pdb_00008jfw; 
				pdb_00008jfy; pdb_00008rbx; pdb_00008rbz; pdb_00008rc4; pdb_00008so0; pdb_00008sw5; pdb_00008sw6; pdb_00008ttb; pdb_00008twe; pdb_00008twi; pdb_00008u1x; pdb_00008u5g; 
				pdb_00008u89; pdb_00008uwb; pdb_00008yjb; pdb_00009b9g; pdb_00009chu; pdb_00009chv; pdb_00009chx
			
			

			» more