PROSITE logo

PROSITE entry PS00126


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] PDEASE_I_1
Accession [info] PS00126
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-JUL-1998 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00116

Name and characterization of the entry

Description [info] 3'5'-cyclic nucleotide phosphodiesterase domain signature.
Pattern [info] 
H-D-[LIVMFY]-x-H-x-[AG]-x(2)-[NQ]-x-[LIVMFY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 102 in 102 different sequences
Number of true positive hits 101 in 101 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 2
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.02 %
Recall (true positives / (true positives + false negatives)) 98.06 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 101 sequences 

PDE10_HUMAN (Q9Y233), PDE10_MOUSE (Q8CA95), PDE10_RAT   (Q9QYJ6), 

PDE11_DROME (Q9VJ79), PDE11_HUMAN (Q9HCR9), PDE11_MOUSE (P0C1Q2), 
PDE11_RAT   (Q8VID6), PDE11_TAKRU (Q1KKS3), PDE1A_BOVIN (P14100), 
PDE1A_HUMAN (P54750), PDE1A_MOUSE (Q61481), PDE1B_BOVIN (Q01061), 
PDE1B_CRIGR (Q64395), PDE1B_HUMAN (Q01064), PDE1B_MOUSE (Q01065), 
PDE1B_RAT   (Q01066), PDE1C_HUMAN (Q14123), PDE1C_MOUSE (Q64338), 
PDE1C_RAT   (Q63421), PDE1_CAEEL  (O18696), PDE1_DROME  (B7YZV4), 
PDE2A_BOVIN (P14099), PDE2A_HUMAN (O00408), PDE2A_MOUSE (Q922S4), 
PDE2A_RAT   (Q01062), PDE2_CAEEL  (P30645), PDE2_DICDI  (Q23917), 
PDE2_YEAST  (P06776), PDE3A_HUMAN (Q14432), PDE3A_MOUSE (Q9Z0X4), 
PDE3A_RAT   (Q62865), PDE3B_HUMAN (Q13370), PDE3B_MOUSE (Q61409), 
PDE3B_RAT   (Q63085), PDE3_CAEEL  (Q8I0P7), PDE3_DICDI  (B0G0Y8), 
PDE4A_DROME (Q9W4T4), PDE4A_HUMAN (P27815), PDE4A_MOUSE (O89084), 
PDE4A_RAT   (P54748), PDE4B_DROME (P12252), PDE4B_HUMAN (Q07343), 
PDE4B_RAT   (P14646), PDE4C_DROME (Q9W4S9), PDE4C_HUMAN (Q08493), 
PDE4C_MOUSE (Q3UEI1), PDE4C_RAT   (P14644), PDE4D_HUMAN (Q08499), 
PDE4D_MOUSE (Q01063), PDE4D_RAT   (P14270), PDE4E_DROME (Q8IRU4), 
PDE4_CAEEL  (Q22000), PDE4_DICDI  (Q86H13), PDE5A_BOVIN (Q28156), 
PDE5A_CANLF (O77746), PDE5A_HUMAN (O76074), PDE5A_MOUSE (Q8CG03), 
PDE5A_RAT   (O54735), PDE5_CAEEL  (P91119), PDE6A_BOVIN (P11541), 
PDE6A_CANLF (Q28263), PDE6A_HUMAN (P16499), PDE6A_MOUSE (P27664), 
PDE6B_BOVIN (P23439), PDE6B_CANLF (P33726), PDE6B_HUMAN (P35913), 
PDE6B_MOUSE (P23440), PDE6C_BOVIN (P16586), PDE6C_CHICK (P52731), 
PDE6C_HUMAN (P51160), PDE6C_MOUSE (Q91ZQ1), PDE6_CAEEL  (Q9N2V9), 
PDE6_DROAN  (B3LVW5), PDE6_DROER  (B3P3K2), PDE6_DROGR  (B4JXX2), 
PDE6_DROME  (Q9VFI9), PDE6_DROMO  (B4K9L4), PDE6_DROPE  (B4G4E5), 
PDE6_DROPS  (Q298P4), PDE6_DROSE  (B4HEM4), PDE6_DROSI  (B4QZU1), 
PDE6_DROVI  (B4LVU6), PDE6_DROWI  (B4NAL6), PDE6_DROYA  (B4PSS5), 
PDE7A_HUMAN (Q13946), PDE7A_MOUSE (P70453), PDE7A_RAT   (O08593), 
PDE7B_HUMAN (Q9NP56), PDE7B_MOUSE (Q9QXQ1), PDE8A_HUMAN (O60658), 
PDE8A_MOUSE (O88502), PDE8B_HUMAN (O95263), PDE8B_MOUSE (E9Q4S1), 
PDE9A_DROME (Q9I7S6), PDE9A_HUMAN (O76083), PDE9A_MOUSE (O70628), 
PDE9A_PANTR (H2QL32), PDE9A_RAT   (Q8QZV1), PDEB_PLAF7  (Q8I6Z7), 
PDED_PLAF7  (Q8IKD3), PDEG_PLAYE  (A0A077YBL0)
» more

UniProtKB/Swiss-Prot
False negative sequences		 2 sequences 

PDE8_DROME  (Q6NNF2), PDEA_PLAF7  (Q8I5V4)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			1 sequence
			


			
PDE4A_CAVPO (O89085)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			1 sequence
			


			
DNAE2_BRADU (Q89QU8)


				
	

	

		PDB
[Detailed view]		
		
			663 PDB
			


			1F0J; 1MKD; 1OYN; 1PTW; 1Q9M; 1RKP; 1RO6; 1RO9; 1ROR; 1SO2; 1SOJ; 1T9R; 
			
				1T9S; 1TAZ; 1TB5; 1TB7; 1TBB; 1TBF; 1UDT; 1UDU; 1UHO; 1XLX; 1XLZ; 1XM4; 
				1XM6; 1XMU; 1XMY; 1XN0; 1XOM; 1XON; 1XOQ; 1XOR; 1XOS; 1XOT; 1XOZ; 1XP0; 
				1Y2B; 1Y2C; 1Y2D; 1Y2E; 1Y2H; 1Y2J; 1Y2K; 1Z1L; 1ZKL; 1ZKN; 2CHM; 2FM0; 
				2FM5; 2H40; 2H42; 2H44; 2HD1; 2O8H; 2OUN; 2OUP; 2OUQ; 2OUR; 2OUS; 2OUU; 
				2OVV; 2OVY; 2QYK; 2QYL; 2QYM; 2QYN; 2WEY; 2Y0J; 2YY2; 3B2R; 3BJC; 3D3P; 
				3DY8; 3DYL; 3DYN; 3DYQ; 3DYS; 3ECM; 3ECN; 3FRG; 3G3N; 3G45; 3G4G; 3G4I; 
				3G4K; 3G4L; 3G58; 3GWT; 3HC8; 3HDZ; 3HMV; 3HQW; 3HQY; 3HQZ; 3HR1; 3I8V; 
				3IAD; 3IAK; 3IBJ; 3ITM; 3ITU; 3JAB; 3JBQ; 3JSI; 3JSW; 3JWQ; 3JWR; 3K3E; 
				3K3H; 3K4S; 3KKT; 3LXG; 3LY2; 3N3Z; 3O0J; 3O56; 3O57; 3QI3; 3QI4; 3QPN; 
				3QPO; 3QPP; 3SHY; 3SHZ; 3SIE; 3SL3; 3SL4; 3SL5; 3SL6; 3SL8; 3SN7; 3SNI; 
				3SNL; 3TGE; 3TGG; 3TVX; 3UI7; 3UUO; 3V9B; 3W5E; 3WD9; 3WI2; 3WS8; 3WS9; 
				3WYK; 3WYL; 3WYM; 4AEL; 4AJD; 4AJF; 4AJG; 4AJM; 4BBX; 4C1I; 4D08; 4D09; 
				4DDL; 4DFF; 4E90; 4FCB; 4FCD; 4G2J; 4G2L; 4G2W; 4G2Y; 4GH6; 4HEU; 4HF4; 
				4HTX; 4HTZ; 4I9Z; 4IA0; 4JIB; 4KP6; 4LKQ; 4LLJ; 4LLK; 4LLP; 4LLX; 4LM0; 
				4LM1; 4LM2; 4LM3; 4LM4; 4MD6; 4MRW; 4MRZ; 4MS0; 4MSA; 4MSC; 4MSE; 4MSH; 
				4MSN; 4MUW; 4MVH; 4MYQ; 4NPV; 4NPW; 4NW7; 4OEW; 4OEX; 4OGB; 4P0N; 4P1R; 
				4PHW; 4PM0; 4QGE; 4TPM; 4TPP; 4W1O; 4WCU; 4WN1; 4WZI; 4X0F; 4XY2; 4Y2B; 
				4Y86; 4Y87; 4Y8C; 4YQH; 4YS7; 4ZO5; 5AXP; 5AXQ; 5B25; 5B4K; 5B4L; 5C1W; 
				5C28; 5C29; 5C2A; 5C2E; 5C2H; 5DH4; 5DH5; 5EDE; 5EDG; 5EDH; 5EDI; 5I2R; 
				5JO3; 5K1I; 5K32; 5K6J; 5K9R; 5LAQ; 5LBO; 5OHJ; 5SDU; 5SDV; 5SDW; 5SDX; 
				5SDY; 5SDZ; 5SE0; 5SE1; 5SE2; 5SE3; 5SE4; 5SE5; 5SE6; 5SE7; 5SE8; 5SE9; 
				5SEA; 5SEB; 5SEC; 5SED; 5SEE; 5SEF; 5SEG; 5SEH; 5SEI; 5SEJ; 5SEK; 5SEL; 
				5SEM; 5SEN; 5SEO; 5SEP; 5SEQ; 5SER; 5SES; 5SET; 5SEU; 5SEV; 5SEW; 5SEX; 
				5SEY; 5SEZ; 5SF0; 5SF1; 5SF2; 5SF3; 5SF4; 5SF5; 5SF6; 5SF7; 5SF8; 5SF9; 
				5SFA; 5SFB; 5SFC; 5SFD; 5SFE; 5SFF; 5SFG; 5SFH; 5SFI; 5SFJ; 5SFK; 5SFL; 
				5SFM; 5SFN; 5SFO; 5SFP; 5SFQ; 5SFR; 5SFS; 5SFT; 5SFU; 5SFV; 5SFW; 5SFX; 
				5SFY; 5SFZ; 5SG0; 5SG1; 5SG2; 5SG3; 5SG4; 5SG5; 5SG6; 5SG7; 5SG8; 5SG9; 
				5SGB; 5SGC; 5SGD; 5SGE; 5SGF; 5SGG; 5SGH; 5SGI; 5SGJ; 5SGK; 5SGL; 5SGM; 
				5SGN; 5SGO; 5SGP; 5SGQ; 5SGR; 5SGS; 5SGT; 5SGU; 5SGV; 5SGW; 5SGX; 5SGY; 
				5SGZ; 5SH0; 5SH1; 5SH2; 5SH3; 5SH4; 5SH5; 5SH6; 5SH7; 5SH8; 5SH9; 5SHA; 
				5SHB; 5SHC; 5SHD; 5SHE; 5SHF; 5SHG; 5SHH; 5SHI; 5SHJ; 5SHK; 5SHL; 5SHM; 
				5SHN; 5SHO; 5SHP; 5SHQ; 5SHR; 5SHS; 5SHT; 5SHU; 5SHV; 5SHW; 5SHX; 5SHY; 
				5SHZ; 5SI0; 5SI1; 5SI2; 5SI3; 5SI4; 5SI5; 5SI6; 5SI7; 5SI8; 5SI9; 5SIA; 
				5SIB; 5SID; 5SIE; 5SIF; 5SIG; 5SIH; 5SII; 5SIJ; 5SIK; 5SIL; 5SIM; 5SIN; 
				5SIO; 5SIP; 5SIQ; 5SIR; 5SIS; 5SIT; 5SIU; 5SIV; 5SIW; 5SIX; 5SIY; 5SIZ; 
				5SJ0; 5SJ1; 5SJ2; 5SJ3; 5SJ4; 5SJ5; 5SJ6; 5SJ7; 5SJ8; 5SJ9; 5SJA; 5SJB; 
				5SJC; 5SJD; 5SJE; 5SJF; 5SJG; 5SJH; 5SJI; 5SJJ; 5SJK; 5SJL; 5SJM; 5SJN; 
				5SJO; 5SJP; 5SJQ; 5SJR; 5SJS; 5SJT; 5SJU; 5SJV; 5SJW; 5SJX; 5SJY; 5SJZ; 
				5SK0; 5SK1; 5SK2; 5SK3; 5SK4; 5SK5; 5SK6; 5SK7; 5SK8; 5SK9; 5SKA; 5SKB; 
				5SKC; 5SKD; 5SKE; 5SKF; 5SKG; 5SKH; 5SKI; 5SKJ; 5SKK; 5SKL; 5SKM; 5SKN; 
				5SKO; 5SKP; 5SKQ; 5SKR; 5SKS; 5SKT; 5SKU; 5SKV; 5TKB; 5TZ3; 5TZA; 5TZC; 
				5TZH; 5TZW; 5TZX; 5TZZ; 5U00; 5U7D; 5U7I; 5U7J; 5U7K; 5U7L; 5UOY; 5UP0; 
				5UWF; 5VP0; 5VP1; 5W6E; 5WH5; 5WH6; 5WQA; 5XKM; 5XUI; 5XUJ; 5ZNL; 5ZZ2; 
				6A3N; 6ACB; 6AKR; 6B96; 6B97; 6B98; 6BLF; 6BOJ; 6C7D; 6C7E; 6C7F; 6C7G; 
				6C7I; 6C7J; 6CYB; 6CYC; 6CYD; 6F6U; 6F8R; 6F8T; 6F8U; 6F8V; 6F8W; 6F8X; 
				6FDC; 6FDI; 6FE7; 6FEB; 6FET; 6FT0; 6FTA; 6FTW; 6FW3; 6HWO; 6IAG; 6IBF; 
				6IJH; 6IJI; 6IM6; 6IMB; 6IMD; 6IMI; 6IMO; 6IMR; 6IMT; 6IND; 6INK; 6INM; 
				6IWI; 6K9U; 6KDX; 6KDZ; 6KE0; 6KJZ; 6KK0; 6KO0; 6KO1; 6KZE; 6L6E; 6LRM; 
				6LZZ; 6MSA; 6MSC; 6MZB; 6NJH; 6NJI; 6NJJ; 6RCW; 6VBI; 6X88; 6ZBA; 6ZND; 
				6ZQZ; 7A8Q; 7A9V; 7AAG; 7AB9; 7ABD; 7ABE; 7ABJ; 7AY6; 7B9H; 7BPI; 7CBJ; 
				7CBQ; 7CWA; 7CWF; 7CWG; 7EG0; 7EG1; 7EG4; 7F0I; 7F2K; 7F2L; 7F2M; 7FAQ; 
				7FAR; 7JSN; 7KWE; 7L27; 7L28; 7L29; 7LRC; 7LRD; 7QPF; 7QPM; 7QPQ; 7QPV; 
				7QQ4; 7VSL; 7VTV; 7VTW; 7VTX; 7W4X; 7W4Y; 7XAA; 7XAB; 7XBB; 7YQF; 7YSX; 
				8BPY; 8DI4; 8K4C; 8K4H; 8OEG; 8SYC; 8UFI; 8UGB; 8UGS; 8ULG; 8W4Q; 8W4R; 
				8W4S; 8W4T; 8YLC
			
			

			» more