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PROSITE entry PS00127


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General information about the entry

Entry name [info] RNASE_PANCREATIC
Accession [info] PS00127
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-1990 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00118

Name and characterization of the entry

Description [info] Pancreatic ribonuclease family signature.
Pattern [info] 
C-K-x(2)-N-T-F.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 197 in 197 different sequences
Number of true positive hits 189 in 189 different sequences
Number of 'unknown' hits 0
Number of false positive hits 8 in 8 different sequences
Number of false negative sequences 0
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 95.94 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] active_site at position 2
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 189 sequences 

AMPS1_LITPI (P85072), AMPS2_LITPI (P85073), AMPS3_LITPI (P85074), 

AMPS4_LITPI (P85075), ANG1_BOVIN  (P10152), ANG2_BOVIN  (P80929), 
ANG2_MOUSE  (Q64438), ANG3_MOUSE  (P97802), ANG4_MOUSE  (Q3TMQ6), 
ANGI_AOTTR  (Q8WN61), ANGI_CHICK  (P27043), ANGI_CHLAE  (Q8WN66), 
ANGI_COLGU  (Q861Y5), ANGI_GORGO  (Q71MJ0), ANGI_HORSE  (Q5VI84), 
ANGI_HUMAN  (P03950), ANGI_MACMU  (Q8WN63), ANGI_MIOTA  (Q8WN65), 
ANGI_MOUSE  (P21570), ANGI_PANTR  (Q8WME8), ANGI_PAPHA  (Q8WN64), 
ANGI_PIG(P31346), ANGI_PONPY  (Q8WN67), ANGI_RABIT  (P31347), 
ANGI_RHIAV  (Q861Y1), ANGI_RHIBE  (Q861Y2), ANGI_RHIRO  (Q861Y3), 
ANGI_SAGOE  (Q8WN62), ANGI_SAISC  (Q8WN60), ANGI_TRAFR  (Q861Y4), 
ECP1_MOUSE  (P97426), ECP2_MOUSE  (P97425), ECP3_MOUSE  (O35290), 
ECP_GORGO   (P47778), ECP_HUMAN   (P12724), ECP_MACFA   (P47779), 
ECP_MACNE   (Q8SPY9), ECP_PANTR   (P47780), ECP_PONPY   (P47781), 
ECP_RAT (P70709), LECS_RANJA  (P18839), RNAS1_ABRJE (Q9WUR3), 
RNAS1_ACOCA (Q9WTT5), RNAS1_AEPME (P07847), RNAS1_ALCAA (P00667), 
RNAS1_ANTAM (P00668), RNAS1_ATEGE (Q8SQ06), RNAS1_AXIPR (P87351), 
RNAS1_BALAC (P00673), RNAS1_BISBI (P61824), RNAS1_BOSTR (P07849), 
RNAS1_BOVIN (P61823), RNAS1_BUBBU (P00657), RNAS1_CAMBA (P67929), 
RNAS1_CAMDR (P67928), RNAS1_CAPCA (P00664), RNAS1_CAPHI (P67926), 
RNAS1_CEREL (P00663), RNAS1_CHEMY (P84844), RNAS1_CHESE (P04061), 
RNAS1_CHICH (P00675), RNAS1_CHINI (Q9WUV3), RNAS1_CHLAE (P61821), 
RNAS1_CHOHO (P00685), RNAS1_CONTA (P00660), RNAS1_CRIGR (P24717), 
RNAS1_DAMDA (P00665), RNAS1_DAMKO (P00659), RNAS1_EUDTH (P07848), 
RNAS1_GALMU (P00680), RNAS1_GERGM (Q9WUX4), RNAS1_GERNI (Q9WUS2), 
RNAS1_GIRCA (P00662), RNAS1_GLIGL (Q9WUS1), RNAS1_GORGO (Q8SQ13), 
RNAS1_HIPAM (P00672), RNAS1_HORSE (P00674), RNAS1_HUMAN (P07998), 
RNAS1_HYDHY (P00677), RNAS1_HYSCR (P04060), RNAS1_IGUIG (P80287), 
RNAS1_LAGLA (Q8SQ05), RNAS1_LEMCA (Q8SQ04), RNAS1_LEOED (Q9WUS3), 
RNAS1_MACMU (Q8SPN5), RNAS1_MESAU (P00682), RNAS1_MIOTA (P61822), 
RNAS1_MOUSE (P00683), RNAS1_MUSPA (Q9QYX3), RNAS1_MUSSA (Q9QYX2), 
RNAS1_MYOCO (P00676), RNAS1_MYOGA (Q9WUR4), RNAS1_NIVCR (Q9WUV4), 
RNAS1_NOMLE (Q8SQ11), RNAS1_NOTRU (B3EWJ0), RNAS1_ONDZI (P00681), 
RNAS1_ORYLE (Q29606), RNAS1_OSPRU (P00686), RNAS1_PANTR (Q8SQ14), 
RNAS1_PAPHA (Q8SQ09), RNAS1_PERLE (Q9WUV5), RNAS1_PIG   (P00671), 
RNAS1_PONPY (Q8SQ12), RNAS1_PROGU (P04059), RNAS1_PYGNE (Q8SPN4), 
RNAS1_RANTA (P00666), RNAS1_SAGOE (Q8SQ07), RNAS1_SAISC (Q8SQ08), 
RNAS1_SEMEN (P19644), RNAS1_SHEEP (P67927), RNAS1_SPAEH (P16414), 
RNAS1_SUNME (Q8VD83), RNAS1_TRAOR (P00658), RNAS1_URARU (Q9WUX6), 
RNAS2_AOTTR (O18937), RNAS2_CALJA (Q8SPY2), RNAS2_CHLAE (Q8SPY6), 
RNAS2_GORGO (P47782), RNAS2_HUMAN (P10153), RNAS2_MACFA (P47783), 
RNAS2_MACNE (Q8SPY5), RNAS2_MOUSE (O35291), RNAS2_NOMLE (Q8SPY8), 
RNAS2_PANTR (P47785), RNAS2_PAPHA (Q8SPY7), RNAS2_PONPY (P47784), 
RNAS2_SAGLB (Q8SPY3), RNAS2_SAGOE (P47786), RNAS2_SAISC (Q8SPY4), 
RNAS4_BOVIN (P15467), RNAS4_HUMAN (P34096), RNAS4_MOUSE (Q9JJH1), 
RNAS4_PANTR (Q8HZQ0), RNAS4_PIG   (P15468), RNAS4_PONAB (Q5NVS4), 
RNAS4_RAT   (O55004), RNAS6_AOTTR (O46528), RNAS6_BOVIN (P08904), 
RNAS6_CHLAE (O46534), RNAS6_GORGO (O46532), RNAS6_HUMAN (Q93091), 
RNAS6_MACMU (O46533), RNAS6_MIOTA (O46531), RNAS6_MOUSE (Q9D244), 
RNAS6_PANTR (O46525), RNAS6_PAPHA (O46527), RNAS6_PIG   (P81649), 
RNAS6_PONPY (O46526), RNAS6_SAGOE (O46530), RNAS6_SAISC (O46529), 
RNAS7_HUMAN (Q9H1E1), RNAS8_AOTTR (Q8SPZ5), RNAS8_CHLAE (Q8SPZ6), 
RNAS8_HUMAN (Q8TDE3), RNAS8_MIOTA (Q8SPZ7), RNAS8_PANTR (Q8SPZ8), 
RNAS8_PONPY (A1YLB9), RNAS8_SAGOE (Q8SPZ4), RNASL_AQUCT (P14626), 
RNASO_AQUCT (P11916), RNBR_AXIPR  (P87350), RNBR_BOVIN  (P39873), 
RNBR_CAPCA  (P79351), RNBR_GIRCA  (Q29542), RNBR_SHEEP  (Q29543), 
RNL2_CHICK  (P81476), RNP30_LITPI (P22069), RNS1A_CAVPO (P00678), 
RNS1A_RATEX (Q8VD93), RNS1A_RATFU (Q8VD91), RNS1B_CAVPO (P00679), 
RNS1B_PYGNE (Q8SPN3), RNS1B_RAT   (P00684), RNS1B_RATEX (Q9WUX3), 
RNS1B_RATTI (Q8VD84), RNS1D_RAT   (Q8VD88), RNS1D_RATEX (Q8VD92), 
RNS1D_RATRT (Q8VD86), RNS1D_RATTI (Q8VD85), RNS1G_RAT   (Q8VD89), 
RNS1G_RATFU (Q8VD90), RNS1G_RATRT (Q8VD87), RNS2B_MOUSE (O35292), 
RNSL3_DANRE (A5HAK0), RNS_BOVIN   (P00669), RNS_CEPSI   (Q29539), 
RNS_GIRCA   (Q29535), RNS_SAITA   (Q29538), RSFR_CHICK  (P30374)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 5 sequences 

GLYL_BOVIN  (P59760), LGEN_BOVIN  (P59761), RNAS1_ODOVI (P19640), 

RNAS2_PIG   (P80551), RNL1_PIG(P15466)
» more

UniProtKB/Swiss-Prot
False positive sequences		 8 sequences 

CAPSD_RCNMV (P22955), DAW1_CHLRE  (Q3Y8L7), DIAP3_HUMAN (Q9NSV4), 

DIAP3_MOUSE (Q9Z207), DIAP3_RAT   (F1LVW7), LCAT2_ARATH (Q4VCM1), 
RL32_ONYPE  (Q6YR20), VIT_ONCMY   (Q92093)
» more

PDB
[Detailed view]		 476 PDB

11BA; 11BG; 1A2W; 1A4Y; 1A5Q; 1AFK; 1AFL; 1AFU; 1AGI; 1ANG; 1AQP; 1AWZ; 1B1I; 1B1J; 1B6V; 1BC4; 1BEL; 1BSR; 1BZQ; 1C0B; 1C0C; 1C9V; 1C9X; 1CJQ; 1CJR; 1D5D; 1D5E; 1D5H; 1DFJ; 1DY5; 1DYT; 1DZA; 1E21; 1EIC; 1EID; 1EIE; 1EOS; 1EOW; 1F0V; 1FEV; 1FS3; 1GIO; 1GQV; 1GV7; 1H0D; 1H1H; 1H52; 1H53; 1H8X; 1HBY; 1HI2; 1HI3; 1HI4; 1HI5; 1J7Z; 1J80; 1J81; 1J82; 1JN4; 1JS0; 1JVT; 1JVU; 1JVV; 1K2A; 1K58; 1K59; 1K5A; 1K5B; 1KF2; 1KF3; 1KF4; 1KF5; 1KF7; 1KF8; 1KH8; 1KM8; 1KM9; 1LSQ; 1M07; 1N1X; 1N3Z; 1O0F; 1O0H; 1O0M; 1O0N; 1O0O; 1ONC; 1PU3; 1QHC; 1QMT; 1QWQ; 1R3M; 1R5C; 1R5D; 1RAR; 1RAS; 1RAT; 1RBB; 1RBC; 1RBD; 1RBE; 1RBF; 1RBG; 1RBH; 1RBI; 1RBJ; 1RBN; 1RBW; 1RBX; 1RCA; 1RCN; 1RHA; 1RHB; 1RNC; 1RND; 1RNF; 1RNM; 1RNN; 1RNO; 1RNQ; 1RNU; 1RNV; 1RNW; 1RNX; 1RNY; 1RNZ; 1ROB; 1RPF; 1RPG; 1RPH; 1RRA; 1RSM; 1RTA; 1RTB; 1RUV; 1SRN; 1SSA; 1SSB; 1SSC; 1TQ9; 1U1B; 1UN4; 1UN5; 1W4O; 1W4P; 1W4Q; 1WBU; 1XPS; 1XPT; 1Y92; 1Y94; 1YMN; 1YMR; 1YMW; 1YV4; 1YV6; 1YV7; 1Z3L; 1Z3M; 1Z3P; 1Z6D; 1Z6S; 1Z7X; 2AAS; 2ANG; 2APQ; 2BEX; 2BLP; 2BLZ; 2BWK; 2BWL; 2BZZ; 2C01; 2C02; 2C05; 2E0J; 2E0L; 2E0M; 2E0O; 2E33; 2E3W; 2G4W; 2G4X; 2G8Q; 2G8R; 2GMK; 2HKY; 2I5S; 2J4T; 2K11; 2KB5; 2KB6; 2LFJ; 2LT5; 2LVZ; 2NUI; 2OP2; 2OQF; 2P42; 2P43; 2P44; 2P45; 2P46; 2P47; 2P48; 2P49; 2P4A; 2P6Z; 2P7S; 2Q4G; 2QCA; 2RAT; 2RLN; 2RNF; 2RNS; 2VQ9; 2W5G; 2W5I; 2W5K; 2W5L; 2W5M; 2XOG; 2XOI; 2ZPO; 3A1R; 3BCM; 3BCO; 3BCP; 3D6O; 3D6P; 3D6Q; 3D7B; 3D8Y; 3D8Z; 3DH5; 3DH6; 3DI7; 3DI8; 3DI9; 3DIB; 3DIC; 3DJO; 3DJP; 3DJQ; 3DJV; 3DJX; 3DXG; 3DXH; 3EUX; 3EUY; 3EUZ; 3EV0; 3EV1; 3EV2; 3EV3; 3EV4; 3EV5; 3EV6; 3F8G; 3FD7; 3FKZ; 3FL0; 3FL1; 3FL3; 3HG6; 3I67; 3I6F; 3I6H; 3I6J; 3I7W; 3I7X; 3I7Y; 3JW1; 3LXO; 3MWQ; 3MWR; 3MX8; 3MZQ; 3MZR; 3OQY; 3OQZ; 3OR0; 3PHN; 3QL1; 3QL2; 3QSK; 3RAT; 3RH1; 3RID; 3RN3; 3RSD; 3RSK; 3RSP; 3SNF; 3SRN; 3TSR; 3U00; 3ZBV; 3ZBW; 4A2O; 4A2Y; 4AHD; 4AHE; 4AHF; 4AHG; 4AHH; 4AHJ; 4AHK; 4AHL; 4AHM; 4AHN; 4AO1; 4AOH; 4B36; 4G8V; 4G8Y; 4G90; 4J5Z; 4J60; 4J61; 4J62; 4J63; 4J64; 4J65; 4J66; 4J67; 4J68; 4J69; 4J6A; 4K7L; 4K7M; 4KXH; 4L55; 4MXF; 4N4C; 4O36; 4O37; 4OKF; 4OOH; 4OT4; 4OWZ; 4OXB; 4OXF; 4PEQ; 4PER; 4POU; 4QH3; 4RAT; 4RSD; 4RSK; 4RTE; 4S0Q; 4S18; 4SRN; 4WYN; 4WYP; 4WYZ; 4X08; 4X09; 4YGW; 4ZZ4; 5AR6; 5ARJ; 5ARK; 5ARL; 5D6U; 5D97; 5E13; 5E5E; 5E5F; 5EOP; 5EPZ; 5EQO; 5ET4; 5JLG; 5JMG; 5JML; 5M9A; 5M9G; 5M9J; 5M9M; 5M9P; 5M9Q; 5M9R; 5M9S; 5M9T; 5M9V; 5NA9; 5NJ7; 5OAB; 5OBC; 5OBD; 5OBE; 5OGH; 5OLD; 5RAT; 5RSA; 6ENP; 6ETK; 6ETL; 6ETM; 6ETN; 6ETO; 6ETP; 6ETQ; 6ETR; 6F60; 6GOK; 6MV6; 6MV7; 6PVU; 6PVV; 6PVW; 6PVX; 6QE9; 6QMN; 6RAT; 6RSA; 6SSO; 6XHC; 6XHD; 6XHE; 6XHF; 6XVX; 6XW0; 6YO1; 7NPM; 7OR6; 7ORD; 7P4R; 7P8R; 7PNI; 7PNJ; 7PNP; 7PNR; 7Q75; 7Q76; 7Q77; 7Q78; 7Q79; 7Q7A; 7Q7B; 7QHR; 7QPW; 7QPY; 7QPZ; 7QQ0; 7QWH; 7R1P; 7RAT; 7RSA; 7TY1; 7Z6D; 7Z6G; 8AF0; 8C3B; 8F5X; 8FHM; 8GC9; 8GGG; 8OO3; 8OO4; 8OQC; 8OQD; 8OQE; 8OQF; 8OQG; 8PX0; 8R5V; 8RAT; 8RSA; 8S96; 9EO5; 9EO8; 9RAT; 9RSA
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