PROSITE entry PS00131
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS00131 |
| Entry name [info] | CARBOXYPEPT_SER_SER |
| Accession [info] | PS00131 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-FEB-2003 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00122 |
| Associated ProRule [info] | PRU10074 |
Name and characterization of the entry
| Description [info] | Serine carboxypeptidases, serine active site. |
| Pattern [info] |
[LIVM]-x-[GSTA]-E-S-Y-[AG]-[GS]. |
Numerical results [info]
| Total number of hits | 172 in 172 different sequences |
| Number of true positive hits | 164 in 164 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 8 in 8 different sequences |
| Number of false negative sequences | 56 |
| Number of 'partial' sequences | 2 |
| Precision (true positives / (true positives + false positives)) | 95.35 % |
| Recall (true positives / (true positives + false negatives)) | 74.55 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 5 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
164 sequences
ACUI_ASPA1 (A0A1L9WN42), ATG42_YEAST (P38109), CBP1_HORVU (P07519), CBP1_ORYSJ (P37890), CBP21_HORVU (P55747), CBP22_HORVU (P55748), CBP23_HORVU (P52711), CBP2_HORVU (P08818), CBP2_WHEAT (P08819), CBP3_HORVU (P21529), CBP3_ORYSJ (P37891), CBP3_WHEAT (P11515), CBPX_ORYSJ (P52712), CBPYA_AJECG (C0NX46), CBPYA_AJECN (A6RGA0), CBPYA_AJEDR (C5GEU5), CBPYA_ARTBC (D4AZ71), CBPYA_ARTGP (E4USS9), CBPYA_ARTOC (C5FWJ1), CBPYA_ASPCL (A1CUJ5), CBPYA_ASPFN (B8NXS9), CBPYA_ASPFU (Q5VJG9), CBPYA_ASPNC (A5AB21), CBPYA_ASPOR (Q2TYA1), CBPYA_ASPTN (Q0CSD3), CBPYA_BLAGS (C5K1Y9), CBPYA_BOTFB (A6RUD7), CBPYA_CHAGB (Q2H9G6), CBPYA_COCP7 (C5P212), CBPYA_COLGM (E3QR43), CBPYA_EMENI (Q96VC4), CBPYA_FUSV7 (C7YQJ2), CBPYA_LEPMJ (E5A7I6), CBPYA_NEOFI (A1DP75), CBPYA_NEUCR (Q7RXW8), CBPYA_PARBA (C1GXD8), CBPYA_PARBD (C1GG77), CBPYA_PARBP (C0SGX7), CBPYA_PENRW (B6HPP6), CBPYA_PHANO (Q0V1R1), CBPYA_PODAN (B2AWD5), CBPYA_PYRO7 (A4RPY8), CBPYA_PYRTR (B2WKF1), CBPYA_SCLS1 (A7F4H5), CBPYA_SORMK (D1ZG13), CBPYA_TALMQ (B6QAN5), CBPYA_TALSN (B8M044), CBPYA_TRIEQ (B8XGR4), CBPYA_TRIRU (Q5J6J0), CBPYA_TRITO (A5YCB8), CBPYA_TRIVH (D4DLI1), CBPYA_UNCRE (C4JNM2), CBPYB_ARTBC (D4ANB6), CBPY_CANAX (P30574), CBPY_KOMPG (P52710), CBPY_SCHPO (O13849), CBPY_YEAST (P00729), CPS1_PENJA (P34946), CPVL_DICDI (Q869Q8), CPVL_HUMAN (Q9H3G5), CPVL_MOUSE (Q9D3S9), CPVL_PONAB (Q5RFE4), CPVL_RAT(Q4QR71), CTS11_CAEEL (P52717), CTS12_CAEEL (P52715), CTS31_CAEEL (P52716), CTS32_CAEEL (P52714), CTS41_CAEEL (Q09991), DPP4_TRIRU (Q5J6J3), KEX1_ARTBC (D4B5L8), KEX1_ARTOC (C5FTV7), KEX1_ASPCL (A1CQL5), KEX1_ASPFC (B0XQ16), KEX1_ASPFU (Q4WTK9), KEX1_ASPNC (A2QPW5), KEX1_ASPOR (Q2UPI1), KEX1_CANGA (Q6FTM9), KEX1_CLAL4 (C4Y8B4), KEX1_COLGM (E3QDT3), KEX1_EMENI (Q5BDJ6), KEX1_EREGS (Q752M5), KEX1_FUSV7 (C7YRS6), KEX1_KLULA (Q6CKK4), KEX1_KOMPG (C4QZV7), KEX1_LEPMJ (E5R540), KEX1_METRA (E9ESM3), KEX1_NEOFI (A1D3I1), KEX1_NEUCR (Q1K722), KEX1_OGAPD (E7R7R2), KEX1_PENRW (B6H7A4), KEX1_PHANO (Q0USX0), KEX1_PICPA (O74702), KEX1_PODAN (B2B762), KEX1_PYRTR (B2W340), KEX1_SCLS1 (A7EYY7), KEX1_SORMK (D1ZEM2), KEX1_TALMQ (B6QQZ9), KEX1_TUBMM (D5G4B1), KEX1_VANPO (A7TLB3), KEX1_YARLI (Q6CFP3), KEX1_YEAS2 (C7GWZ2), KEX1_YEAS8 (C8Z852), KEX1_YEASO (E7NHF8), KEX1_YEAST (P09620), NF314_NAEFO (P42661), PEPF_ASPNG (P52718), PEPS_ARTBC (D4AQA7), PEPS_ASPPH (P52719), PPGB_BOVIN (Q3MI05), PPGB_HUMAN (P10619), PPGB_MOUSE (P16675), RISC_HUMAN (Q9HB40), RISC_MOUSE (Q920A5), RISC_RAT(Q920A6), SCP1_MEDTR (A0A0C3VJP4), SCP20_ARATH (Q8L7B2), SCP21_ARATH (Q9LSV8), SCP22_ARATH (Q1PF08), SCP23_ARATH (O82229), SCP24_ARATH (Q9M099), SCP25_ARATH (Q8L9Y0), SCP26_ARATH (Q9ZQQ0), SCP26_ORYSJ (Q5W727), SCP27_ARATH (Q9SFB5), SCP28_ARATH (Q8S8K6), SCP29_ARATH (Q949Q7), SCP30_ARATH (O23364), SCP31_ARATH (O04084), SCP32_ARATH (Q4PSY2), SCP33_ARATH (Q9LSM9), SCP34_ARATH (Q0WPR4), SCP35_ARATH (Q9LEY1), SCP39_ARATH (Q9SV02), SCP40_ARATH (Q0WRX3), SCP41_ARATH (Q9FH06), SCP42_ARATH (Q9FH05), SCP43_ARATH (Q84W27), SCP44_ARATH (Q9MAR8), SCP45_ARATH (Q93Y09), SCP46_ARATH (Q8VY01), SCP47_ARATH (Q9FFB0), SCP48_ARATH (Q56WF8), SCP49_ARATH (P32826), SCP51_ARATH (Q67Y83), SCP53_ARATH (Q9LXY6), SCP54_ARATH (Q9FFB2), SCPA_ARTBC (D4AIF1), SCPA_TRITO (B6V867), SCPA_TRIVH (D4DD24), SCPB_ARTBC (D4AP52), SCPB_ARTOC (C5FGX1), SCPB_TRIRU (Q5J6J2), SCPC_ARTBC (D4AQ54), SCPD_ARTBC (D4B0Q6), SCPE_ARTBC (D4AZG9), SCPF_ARTBC (D4ASE6), SCPL1_DICDI (Q54DY7), SCPL2_DICDI (Q54VW1), SPCA_ARTOC (C5FW30), SPCA_TRIEQ (A7UKV5), SPCA_TRIRU (Q5J6J1), SXA2_SCHPO (P32825), VCP_AEDAE (P42660), VCP_APIME (C9WMM5)» more
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| UniProtKB/Swiss-Prot False negative sequences |
56 sequences
DAP4_PSEMX (Q6F3I7), HNLS_SORBI (P52708), KEX1_AJECN (A6QX86), KEX1_AJEDR (C5GC75), KEX1_ASPTN (Q0CCR9), KEX1_BLAGS (C5JN54), KEX1_CANAL (Q5AFP8), KEX1_CANAW (C4YTG0), KEX1_CANDC (B9WJJ7), KEX1_CANTT (C5MFP8), KEX1_CHAGB (Q2GYB7), KEX1_COCP7 (C5P635), KEX1_COCPS (E9CS37), KEX1_COPC7 (A8NYP0), KEX1_CRYGW (E6R6G5), KEX1_DEBHA (B5RUL7), KEX1_LACTC (C5DLM9), KEX1_LODEL (A5E751), KEX1_METAQ (E9E1Z2), KEX1_MYCMD (Q4P8U8), KEX1_PARBA (C1GP85), KEX1_PARBD (C1G2I2), KEX1_PARBP (C0SGJ2), KEX1_PHYIT (D0MVS1), KEX1_PICGU (A5DAT0), KEX1_PUCGT (E3L8A5), KEX1_PYRO7 (A4RE47), KEX1_SCHJY (B6K7U7), KEX1_TALSN (B8M719), KEX1_UNCRE (C4JTD3), KEX1_VERA1 (C9S688), KEX1_ZYGRC (C5DT72), SCP10_ARATH (O64810), SCP11_ARATH (Q2V465), SCP12_ARATH (O81009), SCP13_ARATH (Q8H780), SCP14_ARATH (Q9C7D3), SCP15_ARATH (Q9C7D2), SCP16_ARATH (Q9C7D4), SCP17_ARATH (Q9C7D6), SCP18_ARATH (Q9C7Z9), SCP19_ARATH (Q8VZU3), SCP1_ARATH (Q8RWJ6), SCP36_ARATH (Q9SV04), SCP37_ARATH (Q84WF0), SCP38_ARATH (Q9ZUG3), SCP3_ARATH (Q9CAU1), SCP4_ARATH (Q9CAU4), SCP50_ARATH (Q9M9Q6), SCP52_ARATH (Q8S8P0), SCP5_ARATH (Q9CAU2), SCP6_ARATH (Q9CAU0), SCP7_ARATH (Q9SQX6), SCP8_ARATH (Q8RUW5), SCP9_ARATH (O64811), SCPL2_ARATH (Q9CAU3)» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
2 sequences
CBPX_PEA(Q41005), PEP1_ASPNG (P55749) |
| UniProtKB/Swiss-Prot False positive sequences |
8 sequences
CAPSD_TTVV9 (Q9DUC4), CO4A3_HUMAN (Q01955), COMB_STRPN (P36498), COMB_STRR6 (P59654), KT3K_ENTFD (Q3XZZ9), RA213_ARATH (Q9LM15), SYTC_CAEEL (P52709), T4149_TANPA (X2ESR4)» more |
| PDB [Detailed view] |
18 PDB
1AC5; 1BCR; 1BCS; 1IVY; 1WHS; 1WHT; 1WPX; 1YSC; 3SC2; 4AZ0; 4AZ3; 4CI9; 4CIA; 4CIB; 4MWS; 4MWT; 6WIA; 7KDV » more |