PROSITE logo

PROSITE entry PS00144


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] ASN_GLN_ASE_1
Accession [info] PS00144
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00132
Associated ProRule [info] PRU10099

Name and characterization of the entry

Description [info] Asparaginase / glutaminase active site signature 1.
Pattern [info]
[LIVM]-x-{L}-T-G-G-T-[IV]-[AGS].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 129 in 129 different sequences
Number of true positive hits 53 in 53 different sequences
Number of 'unknown' hits 1
Number of false positive hits 75 in 75 different sequences
Number of false negative sequences 18
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 41.41 %
Recall (true positives / (true positives + false negatives)) 74.65 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 7
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
53 sequences

ASP21_YEAST (P0CZ17), ASP22_YEAST (P0CX77), ASP23_YEAST (P0CX78), 
ASP24_YEAST (P0CX79), ASPG1_BACSU (P26900), ASPG1_ECO57 (P0A963), 
ASPG1_ECOLI (P0A962), ASPG1_YEAST (P38986), ASPG2_BACSU (O34482), 
ASPG2_ECOLI (P00805), ASPG2_HAEIN (P43843), ASPG_BACLI  (P30363), 
ASPG_DEIRA  (Q9RRX9), ASPG_DICCH  (P06608), ASPG_DIRIM  (Q9U518), 
ASPG_HELPJ  (Q9ZLB9), ASPG_HELPY  (O25424), ASPG_MYCBO  (P63628), 
ASPG_MYCLE  (Q9X7E6), ASPG_MYCTO  (P9WPX4), ASPG_MYCTU  (P9WPX5), 
ASPG_THEKO  (Q5JIW4), ASPG_WOLSU  (P50286), ASPQ_ACIGL  (P10172), 
ASPQ_DELAC  (P83712), ASPQ_PSEAE  (Q9I407), ASPQ_PSEFA  (O68897), 
ASPQ_PSEPK  (Q88K39), ASPQ_PSES7  (P10182), GATD_ARCFU  (O29380), 
GATD_HALS3  (B0R6H4), GATD_HALSA  (Q9HP20), GATD_HALWD  (Q18GL3), 
GATD_METAC  (Q8TR66), GATD_METBF  (Q46GJ6), GATD_METBU  (Q12X65), 
GATD_METJA  (Q60331), GATD_METKA  (Q8TV84), GATD_METM5  (A4FWR5), 
GATD_METM6  (A9AA46), GATD_METM7  (A6VGK5), GATD_METMA  (Q8PUM7), 
GATD_METMP  (P61400), GATD_METS3  (A5UK11), GATD_METST  (Q2NEH1), 
GATD_METTH  (O26802), GATD_METVS  (A6UPR4), GATD_PYRAB  (Q9V0T9), 
GATD_PYRFU  (Q8U0X0), GATD_PYRHO  (O59132), GATD_THEAC  (Q9HJJ5), 
GATD_THEKO  (Q5JI77), GATD_THEVO  (Q979L8)
» more

UniProtKB/Swiss-Prot
False negative sequences
18 sequences

ASPG_PYRFU  (Q8TZE8), GATD_AERPE  (Q9Y9T8), GATD_METS5  (A4YHH3), 
GATD_NANEQ  (P61401), GATD_PYRAE  (Q8ZY04), GATD_SACS2  (Q97ZH5), 
GATD_SULAC  (Q4J955), GATD_SULIA  (C3N5E7), GATD_SULIK  (C4KH13), 
GATD_SULIL  (C3MPS1), GATD_SULIM  (C3MYR5), GATD_SULIN  (C3NHQ2), 
GATD_SULIY  (C3NE01), GATD_SULTO  (Q971W5), GATD_THEPD  (A1RX40), 
LPP60_HUMAN (Q86U10), LPP60_MOUSE (A0JNU3), LPP60_RAT   (O88202)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

DESPA_DANRE (A0A8M2BID5)

		
UniProtKB/Swiss-Prot
False positive sequences
75 sequences

API10_SOLTU (Q03197), API11_SOLTU (P16348), API1_SOLTU  (Q41480), 
API2_SOLTU  (Q43646), API3_SOLTU  (P58518), API4_SOLTU  (Q43645), 
API5_SOLTU  (P58519), API6_SOLTU  (P58520), API7_SOLTU  (Q41448), 
API8_SOLTU  (P17979), API9_SOLTU  (P58521), APT_BLOPB   (Q493A5), 
APT_CHLAA   (A9WCV7), APT_CLOB1   (A7FY09), APT_CLOBH   (A5I6E1), 
APT_CLOBK   (B1IME3), APT_CLOBL   (A7GHS8), APT_CLOBM   (B1L0A2), 
APT_CLOP1   (Q0TP22), APT_CLOPE   (Q8XJ22), APT_CLOPS   (Q0SRP2), 
APT_DESRM   (A4J2G8), APT_LACLA   (Q9CHT5), APT_LACLM   (A2RIW0), 
APT_LACLS   (Q031A0), APT_LACP3   (Q038P1), APT_LACPL   (Q88VH0), 
APT_LATSS   (Q38W53), APT_LEVBA   (Q03QP8), APT_LIGS1   (Q1WT53), 
APT_METM7   (A6VJW6), APT_MYCBO   (P59959), APT_MYCBP   (A1KLT2), 
APT_MYCSJ   (A3PYX7), APT_MYCSK   (A1UFB6), APT_MYCSS   (Q1B9P7), 
APT_MYCTA   (A5U5T4), APT_MYCTO   (P9WQ06), APT_MYCTU   (P9WQ07), 
APT_PEDPA   (Q03F39), APT_PROM5   (A2BXB1), APT_ROSCS   (A7NG77), 
APT_ROSS1   (A5URA4), APT_SYNC1   (Q3A4N0), APT_UREP2   (B1AJC8), 
APT_UREPA   (Q9PQ02), ATM1_CHAGB  (Q2HIE9), ATRN1_MOUSE (Q6A051), 
CDIA2_BURP2 (I1WVY3), DSCA1_DROME (Q0E9H9), KPRS2_ARCFU (O28853), 
KPRS_AERPE  (Q9YAW0), KPRS_COREF  (Q8FQV2), KPRS_CORGL  (Q8NRU9), 
KPRS_MYCBO  (P65233), KPRS_MYCLE  (Q9CD45), KPRS_MYCTO  (P9WKE2), 
KPRS_MYCTU  (P9WKE3), KPRS_NOSS1  (Q8YN97), KPRS_THEAC  (Q9HLV6), 
KPRS_THEVO  (Q97CA5), MACB_NITEU  (Q82VK1), PPR4_ARATH  (Q9FZ24), 
ROCO5_DICDI (Q1ZXD6), SPI1_SOLTU  (P58514), SPI2_SOLTU  (P58515), 
SPI4_SOLTU  (P58517), SPI5_SOLTU  (Q41484), SPI6_SOLTU  (Q41433), 
SPI7_SOLTU  (P30941), SPIKE_ADECT (Q65914), Y1519_RHILW (B5ZMI8), 
Y1668_ARATH (Q9C9N5), Y2074_RHIJ3 (Q1MHJ7), YCGA_BACSU  (P55908)
» more

PDB
[Detailed view]
86 PDB

1AGX; 1DJO; 1DJP; 1HFJ; 1HFK; 1HFW; 1HG0; 1HG1; 1HO3; 1IHD; 1JAZ; 1JJA; 1JSL; 1JSR; 1NNS; 1O7J; 1WSA; 1ZQ1; 2D6F; 2HIM; 2P2D; 2P2N; 2WLT; 2WT4; 3ECA; 3PGA; 4PGA; 5F52; 5HW0; 5I3Z; 5I48; 5I4B; 5K3O; 5K45; 5K4G; 5K4H; 5MQ5; 5OT0; 6EOK; 6NX6; 6NX7; 6NX8; 6NX9; 6NXA; 6NXB; 6NXC; 6NXD; 6PA2; 6PA3; 6PA4; 6PA5; 6PA6; 6PA8; 6PAB; 6PAC; 6PAE; 6RUD; 6RUE; 6RUF; 6SYH; 6UOD; 6UOG; 6UOH; 6V23; 6V24; 6V25; 6V26; 6V29; 6V2A; 6V2B; 6V5F; 6WYW; 6WYX; 6WYY; 6WYZ; 6WZ4; 6WZ6; 6WZ8; 7M11; 7P9C; 7R57; 7R5Q; 7U6M; 8ECD; 8ECE; 8WGQ
» more