PROSITE entry PS00149

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00149
Entry name [info]	SULFATASE_2
Accession [info]	PS00149
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-DEC-2001 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00117

Name and characterization of the entry

Description [info]	Sulfatases signature 2.
Pattern [info]	G-[YV]-x-[ST]-x(2)-[IVAS]-G-K-x(0,1)-[FYWMK]-[HL].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	54 in 54 different sequences
Number of true positive hits	54 in 54 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	27
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	66.67 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

54 sequences

ARSA_BOVIN  (Q08DD1), ARSA_HUMAN  (P15289), ARSA_MOUSE  (P50428),

ARSB_FELCA  (P33727), ARSB_HUMAN  (P15848), ARSB_MOUSE  (P50429), 
ARSB_RAT(P50430), ARSD_HUMAN  (P51689), ARSF_HUMAN  (P54793), 
ARSG_CANLF  (Q32KH9), ARSG_HUMAN  (Q96EG1), ARSG_MOUSE  (Q3TYD4), 
ARSG_RAT(Q32KJ9), ARSH_CANLF  (Q32KH8), ARSH_HUMAN  (Q5FYA8), 
ARSI_CANLF  (Q32KH7), ARSI_HUMAN  (Q5FYB1), ARSI_MOUSE  (Q32KI9), 
ARSI_RAT(Q32KJ8), ARSJ_HUMAN  (Q5FYB0), ARSJ_MOUSE  (Q8BM89), 
ARSL_HUMAN  (P51690), ARSL_MACFA  (Q60HH5), ARS_CHLRE   (P14217), 
ARS_HEMPU   (P14000), ARS_PSEAE   (P51691), ARS_STRPU   (P50473), 
ARS_VOLCA   (Q10723), ASLA_ECOLI  (P25549), ATSA_KLEAE  (P20713), 
ATSA_KLEPN  (Q9X759), BETC_RHIME  (O69787), GALNS_CANLF (Q32KH5), 
GALNS_HUMAN (P34059), GALNS_PIG   (Q8WNQ7), GALSF_BACTN (Q8A2H2), 
GLCSF_BACTN (Q89YS5), GNS_BOVIN   (Q1LZH9), GNS_CAPHI   (P50426), 
GNS_HUMAN   (P15586), GNS_MOUSE   (Q8BFR4), IDS_HUMAN   (P22304), 
IDS_MOUSE   (Q08890), PLH14_FORAG (T2KMG4), PLH18_FORAG (T2KPK5), 
SPHM_HUMAN  (P51688), STS_HUMAN   (P08842), STS_MOUSE   (P50427), 
STS_RAT (P15589), SULF_CLOP1  (Q0TUK6), SULF_CLOPE  (Q8XNV1), 
YDEN_ECOLI  (P77318), YHJ2_SCHPO  (Q9C0V7), YIDJ_ECOLI  (P31447)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

27 sequences

AGL7_HALVD  (D4GU60), ARSK_BOVIN  (Q148F3), ARSK_CANLF  (Q32KH0),

ARSK_CHICK  (Q5ZK90), ARSK_DANRE  (Q08CJ7), ARSK_HUMAN  (Q6UWY0), 
ARSK_MOUSE  (Q9D2L1), ARSK_RAT(Q32KJ2), ARSK_XENLA  (Q0IHJ2), 
ENDSF_BACTN (Q8A2F6), GALNS_MOUSE (Q571E4), GALNS_RAT   (Q32KJ6), 
HEXSF_BACTN (Q8A7C8), PLH11_FORAG (T2KM04), PLH12_FORAG (T2KN71), 
PLH13_FORAG (T2KPJ9), PLH19_FORAG (T2KMG7), PLH32_FORAG (T2KN90), 
PLH36_FORAG (T2KM26), SULF1_CAEEL (Q21376), SULF1_COTCO (Q90XB6), 
SULF1_DROME (Q9VEX0), SULF1_HUMAN (Q8IWU6), SULF1_MOUSE (Q8K007), 
SULF1_RAT   (Q8VI60), SULF2_HUMAN (Q8IWU5), SULF2_MOUSE (Q8CFG0)

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PDB
[Detailed view]

31 PDB

1AUK; 1E1Z; 1E2S; 1E33; 1E3C; 1FSU; 1HDH; 1N2K; 1N2L; 1P49; 4CXK; 4CXS; 4CXU; 4CYR; 4CYS; 4FDI; 4FDJ; 4MHX; 4MIV; 5AJ9; 5FQL; 5G2V; 6FNY; 6G5Z; 6G60; 6HHM; 6IOZ; 6S20; 7PTH; 7PTJ; 8EG3
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