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PROSITE entry PS00158


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General information about the entry

Entry name [info] ALDOLASE_CLASS_I
Accession [info] PS00158
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00143

Name and characterization of the entry

Description [info] Fructose-bisphosphate aldolase class-I active site.
Pattern [info]
[LIVM]-x-[LIVMFYW]-E-G-x-[LSI]-L-K-[PA]-[SN].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.


Total number of hits 64 in 64 different sequences
Number of true positive hits 64 in 64 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 27
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 70.33 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] Schiff_base at position 9
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
64 sequences

ALDCA_DANRE (Q4KMC8), ALDCB_DANRE (Q8JH70), ALDOA_HUMAN (P04075), 
ALDOA_MOUSE (P05064), ALDOA_PANTR (A5A6I5), ALDOA_PONAB (Q5NVR5), 
ALDOA_RABIT (P00883), ALDOA_RAT   (P05065), ALDOA_SALSA (B5DGM7), 
ALDOB_BOVIN (Q3T0S5), ALDOB_CHICK (P07341), ALDOB_DANRE (Q8JH71), 
ALDOB_HUMAN (P05062), ALDOB_MOUSE (Q91Y97), ALDOB_PONAB (Q5RFA6), 
ALDOB_RABIT (P79226), ALDOB_RAT   (P00884), ALDOB_SHEEP (P52210), 
ALDOB_SPAAU (P53447), ALDOC_CARAU (P53448), ALDOC_HUMAN (P09972), 
ALDOC_MACFA (Q9GKW3), ALDOC_MOUSE (P05063), ALDOC_PANTR (Q5R1X4), 
ALDOC_RAT   (P09117), ALF1_CAEEL  (P54216), ALF1_LETCA  (P53445), 
ALF1_PEA(P46256), ALF1_TOXGO  (Q8I8I2), ALF1_XANAC  (Q8PHB5), 
ALF1_XANCP  (Q8P5Z7), ALF1_XYLFA  (Q9PF52), ALF1_XYLFT  (Q87AI0), 
ALF2_CAEEL  (P46563), ALF2_LETCA  (P53446), ALF2_PEA(P46257), 
ALF2_PLABA  (P49577), ALFC1_ORYSJ (P17784), ALFC1_PEA   (Q01516), 
ALFC2_ORYSJ (Q10A30), ALFC2_PEA   (Q01517), ALFC3_ORYSJ (Q5N725), 
ALFC4_ARATH (F4KGQ0), ALFC5_ARATH (O65581), ALFC6_ARATH (Q9SJQ9), 
ALFC7_ARATH (P22197), ALFC8_ARATH (Q9LF98), ALFC_SPIOL  (P16096), 
ALFP1_ARATH (Q9SJU4), ALFP2_ARATH (Q944G9), ALFP3_ARATH (Q9ZU52), 
ALFP_ORYSJ  (Q40677), ALF_CICAR   (O65735), ALF_DICDI   (Q86A67), 
ALF_DROME   (P07764), ALF_ECHMU   (Q9GP32), ALF_LYMST   (P91759), 
ALF_MAIZE   (P08440), ALF_PLAF7   (Q7KQL9), ALF_PLAFA   (P14223), 
ALF_PLAFK   (Q27744), ALF_SCHMA   (P53442), ALF_SPIOL   (P29356), 
ALF_TRYBB   (P07752)
» more

UniProtKB/Swiss-Prot
False negative sequences
27 sequences

ALF1_CLOAB  (Q97TN4), ALF1_CLOB8  (A6LXU8), ALF1_FUSNN  (Q8RGH3), 
ALF1_OCEIH  (Q8ELI2), ALF1_PORG3  (B2RLG9), ALF1_PORGI  (P60053), 
ALF1_STAA1  (A7X6Y6), ALF1_STAA2  (A6U4Y6), ALF1_STAA3  (Q2FDQ4), 
ALF1_STAA8  (Q2FV17), ALF1_STAA9  (A5IW31), ALF1_STAAB  (Q2YWF3), 
ALF1_STAAC  (Q5HCU6), ALF1_STAAE  (A6QK93), ALF1_STAAM  (P67472), 
ALF1_STAAN  (P99117), ALF1_STAAR  (Q6GDJ7), ALF1_STAAS  (Q6G670), 
ALF1_STAAT  (A8Z3K5), ALF1_STAAW  (Q8NUM5), ALF1_STACT  (Q07159), 
ALF1_STAEQ  (Q5HL21), ALF1_STAES  (Q8CMY5), ALF1_STAHJ  (Q4L9B6), 
ALF1_SYNY3  (P74309), ALF1_TREDE  (Q73QV3), ALFC_CHLRE  (Q42690)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
4 sequences

ALDOA_GADMO (P86980), ALDOA_THUAL (P86979), ALDOC_CHICK (P53449), 
ALFC_PINST  (P84722)
» more

PDB
[Detailed view]
69 PDB

1A5C; 1ADO; 1ALD; 1EWD; 1EX5; 1F2J; 1FBA; 1FDJ; 1J4E; 1QO5; 1XDL; 1XDM; 1XFB; 1ZAH; 1ZAI; 1ZAJ; 1ZAL; 2ALD; 2EPH; 2OT0; 2OT1; 2PC4; 2QUT; 2QUU; 2QUV; 3B8D; 3BV4; 3DFN; 3DFO; 3DFP; 3DFQ; 3DFS; 3DFT; 3LGE; 3TU9; 4ALD; 4D2J; 4TR9; 4TU1; 5KY6; 5TJS; 5TK3; 5TKC; 5TKL; 5TKN; 5TKP; 5TLE; 5TLH; 5TLW; 5TLZ; 5VY5; 6ALD; 6MWQ; 6RNG; 6RS1; 6V20; 6XMH; 6XML; 6XMM; 6XMO; 7K9L; 7K9X; 7KA2; 7KA3; 7KA4; 7VDC; 8D44; 8EHG; 8EW2
» more