PROSITE entry PS00159

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General information about the entry

Entry name [info]	ALDOLASE_KDPG_KHG_1
Accession [info]	PS00159
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-NOV-1995 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00144
Associated ProRule [info]	PRU10118

Name and characterization of the entry

Description [info]	KDPG and KHG aldolases active site.
Pattern [info]	G-[LIVM]-x(3)-E-[LIV]-T-[LF]-R.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.

Total number of hits	21 in 21 different sequences
Number of true positive hits	12 in 12 different sequences
Number of 'unknown' hits	0
Number of false positive hits	9 in 9 different sequences
Number of false negative sequences	1
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	57.14 %
Recall (true positives / (true positives + false negatives))	92.31 %

Comments [info]

Taxonomic range [info]	Archaea, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Site [info]	active_site at position 8
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	12 sequences ALKD_PSEA6 (Q15X88), ALKD_PSEAE (O68283), ALKD_PSEPU (P00885), ALKH_DICD3 (P38448), ALKH_ECO57 (P0A957), ALKH_ECOL6 (P0A956), ALKH_ECOLI (P0A955), ALKH_HAEIN (P44480), ALKH_SHIFL (P0A958), ALKH_TREPA (O83578), ALKH_ZYMMO (Q00384), FBPAP_THEKO (Q8NKR9) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	1 sequence ALKH_BACSU (P50846)
UniProtKB/Swiss-Prot False positive sequences	9 sequences CBPC2_MOUSE (Q8CDK2), CBPC2_XENTR (Q0P4M4), FBPAP_THEON (B6YTP6), NALP5_BOVIN (Q647I9), PP347_ARATH (Q9SMZ2), PRMC_THEVB (Q8DHV7), TLR4_CRIGR (Q9WV82), TLR4_MOUSE (Q9QUK6), TLR4_RAT(Q9QX05) » more
PDB [Detailed view]	8 PDB 1EUA; 1EUN; 1FQ0; 1FWR; 1MXS; 1VHC; 5XSE; 5XSF