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Entry: PS00165

General information about the entry

Entry name [info] DEHYDRATASE_SER_THR
Accession [info] PS00165
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
02-JUN-2021 INFO UPDATE.
PROSITE Doc. [info] PDOC00149

Name and characterization of the entry

Description [info] Serine/threonine dehydratases pyridoxal-phosphate attachment site.
Pattern [info] 
[DESH]-x(4,5)-[STVG]-{EVKD}-[AS]-[FYI]-K-[DLIFSA]-[RLVMF]-[GA]-[LIVMGA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2021_03 which contains 565'254 sequence entries.


Total number of hits 219 in 219 different sequences
Number of true positive hits 191 in 191 different sequences
Number of 'unknown' hits 0
Number of false positive hits 28 in 28 different sequences
Number of false negative sequences 19
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 87.21 %
Recall (true positives / (true positives + false negatives)) 90.95 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] pyridoxal_phosphate at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 191 sequences 

AKS11_ALTAL (V5Y0V0    ), ILVA_BACHD  (Q9KC63    ), ILVA_BACSU  (P37946    ), 

ILVA_BURM1  (P53607    ), ILVA_CORGL  (Q04513    ), ILVA_ECOLI  (P04968    ), 
ILVA_HAEIN  (P46493    ), ILVA_LACLA  (Q02145    ), ILVA_MYCBO  (P66898    ), 
ILVA_MYCLE  (Q9X7F1    ), ILVA_MYCTO  (P9WG94    ), ILVA_MYCTU  (P9WG95    ), 
ILVA_PASMU  (Q9CKJ2    ), ILVA_SALTY  (P20506    ), ILVA_STAA3  (Q2FF63    ), 
ILVA_STAA8  (Q2FWJ9    ), ILVA_STAAB  (Q2YUE8    ), ILVA_STAAC  (Q5HEE0    ), 
ILVA_STAAM  (Q99SJ1    ), ILVA_STAAN  (Q7A4H2    ), ILVA_STAAR  (Q3V7T5    ), 
ILVA_STAAS  (Q3V7T4    ), ILVA_STAAW  (Q8NVI8    ), ILVA_STAEQ  (Q5HMF5    ), 
ILVA_STAES  (Q8CNK9    ), ILVA_STAHJ  (Q4L7U4    ), ILVA_STAS1  (Q49Z16    ), 
LTHAD_PSESP (A4F2N8    ), LTHAD_YEAST (P36007    ), SDH1_YEASX  (P0CF23    ), 
SDHD1_ECOL5 (Q0TF95    ), SDHD1_ECOUT (Q1R901    ), SDHD2_ECOL5 (Q0T953    ), 
SDHD2_ECOUT (Q1R2Q6    ), SDHD_ACIAD  (Q6FDC1    ), SDHD_ACIB5  (B7I8P7    ), 
SDHD_ACIBC  (B2HVC6    ), SDHD_ACIBT  (A3M3B1    ), SDHD_AERHH  (A0KI76    ), 
SDHD_AERS4  (A4SPX2    ), SDHD_BACAC  (C3L7G5    ), SDHD_BACAH  (A0RCF8    ), 
SDHD_BACAN  (Q81S85    ), SDHD_BACC1  (Q73AC5    ), SDHD_BACC2  (B7IR88    ), 
SDHD_BACC3  (C1EPF1    ), SDHD_BACC4  (B7HID8    ), SDHD_BACC7  (B7HMG6    ), 
SDHD_BACCR  (Q81F73    ), SDHD_BACCZ  (Q63D23    ), SDHD_BACHD  (Q9KC12    ), 
SDHD_BACHK  (Q6HKG3    ), SDHD_BACMK  (A9VPH9    ), SDHD_BACSK  (Q5WGL6    ), 
SDHD_BACSU  (P54555    ), SDHD_CHRVO  (Q7NUP9    ), SDHD_CITK8  (A8ACI7    ), 
SDHD_COLP3  (Q47V69    ), SDHD_DESHY  (Q24WR0    ), SDHD_ECO24  (A7ZPH2    ), 
SDHD_ECO45  (B7MH26    ), SDHD_ECO55  (B7LBR9    ), SDHD_ECO57  (Q8XCK5    ), 
SDHD_ECO5E  (B5YYW7    ), SDHD_ECO81  (B7MY25    ), SDHD_ECO8A  (B7M6N5    ), 
SDHD_ECOBW  (C4ZVQ3    ), SDHD_ECODH  (B1X9N9    ), SDHD_ECOHS  (A8A2M0    ), 
SDHD_ECOK1  (A1ADP3    ), SDHD_ECOL6  (Q8FFF4    ), SDHD_ECOLC  (B1IX96    ), 
SDHD_ECOLI  (P00926    ), SDHD_ECOLU  (B7N5W6    ), SDHD_ECOSE  (B6I6R7    ), 
SDHD_ESCF3  (B7LK20    ), SDHD_GEOKA  (Q75TC9    ), SDHD_GEOSE  (Q75TH5    ), 
SDHD_HAES1  (Q0I5V1    ), SDHD_HISS2  (B0UWV3    ), SDHD_LACF3  (B2GBP8    ), 
SDHD_LACPL  (Q88TY1    ), SDHD_OENOB  (Q04G28    ), SDHD_PEDPA  (Q03DF6    ), 
SDHD_PHOLL  (Q7N5H9    ), SDHD_PHOPR  (Q6LHF5    ), SDHD_PSEA7  (A6V271    ), 
SDHD_PSEA8  (B7V2Y0    ), SDHD_PSEAB  (Q02QJ1    ), SDHD_PSEAE  (Q9HYN9    ), 
SDHD_PSEMY  (A4XXF3    ), SDHD_PSEP1  (A5W4Y8    ), SDHD_PSEPG  (B0KGK3    ), 
SDHD_SALA4  (B5EY75    ), SDHD_SALAR  (A9MKH2    ), SDHD_SALCH  (Q57I32    ), 
SDHD_SALDC  (B5FMC1    ), SDHD_SALEP  (B5QU31    ), SDHD_SALG2  (B5RG23    ), 
SDHD_SALHS  (B4TA53    ), SDHD_SALNS  (B4SY68    ), SDHD_SALPA  (Q5PKR3    ), 
SDHD_SALPB  (A9MWI4    ), SDHD_SALPC  (C0Q241    ), SDHD_SALPK  (B5BII6    ), 
SDHD_SALSV  (B4TMW9    ), SDHD_SALTI  (Q8Z2L4    ), SDHD_SALTY  (Q8ZL08    ), 
SDHD_SERP5  (A8GES6    ), SDHD_SHIBS  (Q31YA5    ), SDHD_SHIDS  (Q32DH8    ), 
SDHD_SHIF8  (Q0T2D1    ), SDHD_SHIFL  (Q83MK8    ), SDHD_SHISS  (Q3YZG4    ), 
SDHD_STAS1  (Q4A041    ), SDHD_VIBC3  (A5F0M6    ), SDHD_VIBCB  (A7MYG2    ), 
SDHD_VIBCH  (Q9KL72    ), SDHD_VIBCM  (C3LWD9    ), SDHD_VIBPA  (Q87QA2    ), 
SDHD_YERE8  (A1JJW5    ), SDHL_BOVIN  (Q0VCW4    ), SDHL_DICDI  (Q86B06    ), 
SDHL_HUMAN  (P20132    ), SDHL_MOUSE  (Q8VBT2    ), SDHL_RAT    (P09367    ), 
SDHL_YEAS1  (B3LU13    ), SDHL_YEAS6  (B5VKE8    ), SDHL_YEAS7  (A6ZVB1    ), 
SDHL_YEAS8  (C8ZAU6    ), SDSL_HUMAN  (Q96GA7    ), SRR_ARATH   (Q2PGG3    ), 
SRR_BOVIN   (A0JNI4    ), SRR_HUMAN   (Q9GZT4    ), SRR_MOUSE   (Q9QZX7    ), 
SRR_RAT     (Q76EQ0    ), STDH_YEAST  (P25379    ), TD1_SOLLC   (A0FKE6    ), 
TD2_SOLLC   (P25306    ), TDCB_ECO57  (P0AGF8    ), TDCB_ECOL6  (P0AGF7    ), 
TDCB_ECOLI  (P0AGF6    ), TDCB_SALTY  (P11954    ), TDCB_SHIFL  (P0AGF9    ), 
TDCB_STAA3  (Q2FH01    ), TDCB_STAA8  (Q2FYJ3    ), TDCB_STAAB  (Q2YY67    ), 
TDCB_STAAC  (Q5HFY5    ), TDCB_STAAM  (Q99U50    ), TDCB_STAAN  (Q7A5L8    ), 
TDCB_STAAR  (Q6GGX0    ), TDCB_STAAS  (Q6G9C4    ), TDCB_STAAW  (Q8NWQ4    ), 
TD_NICAT    (Q9AXU4    ), THD1_ARATH  (Q9ZSS6    ), THDH_BLAAD  (O42615    ), 
THDH_SCHPO  (O94634    ), THDH_YEAST  (P00927    ), THNS2_DANRE (Q2YDP8    ), 
THNS2_XENLA (Q5XH07    ), THRC1_ARATH (Q9S7B5    ), THRC2_ARATH (Q9SSP5    ), 
THRC_ASHGO  (Q00063    ), THRC_BACHD  (Q9K7E3    ), THRC_BACSL  (P09123    ), 
THRC_BACSU  (P04990    ), THRC_BUCAI  (P57289    ), THRC_BUCAP  (Q8K9V1    ), 
THRC_BUCBP  (Q89AR5    ), THRC_CORGL  (P23669    ), THRC_ECOLI  (P00934    ), 
THRC_HAEIN  (P44503    ), THRC_HELPJ  (Q9ZMX5    ), THRC_HELPY  (O24924    ), 
THRC_METAC  (Q8TQD4    ), THRC_METGL  (P37145    ), THRC_METJA  (Q58860    ), 
THRC_MYCBO  (P66903    ), THRC_MYCLE  (P45837    ), THRC_MYCS2  (A0R220    ), 
THRC_MYCTO  (P9WG58    ), THRC_MYCTU  (P9WG59    ), THRC_PSEAE  (P29363    ), 
THRC_SCHPO  (Q42598    ), THRC_SERMA  (P27735    ), THRC_SOLTU  (Q9MT28    ), 
THRC_SYNY3  (P74193    ), THRC_YEAST  (P16120    ), TSAL_GEOSL  (Q74FW6    ), 
Y4TJ_SINFN  (P55664    ), YI168_YEAST (P0CF21    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 19 sequences 

SDHD_ACIAC  (A1TPW5    ), SDHD_ACIET  (B9MIR7    ), SDHD_ACISJ  (A1W838    ), 

SDHD_BURL3  (Q396Y3    ), SDHD_BURP0  (A3P975    ), SDHD_BURP1  (Q3JJ76    ), 
SDHD_BURP6  (A3NNQ0    ), SDHD_BURPS  (Q63IF8    ), SDHD_BURTA  (Q2T8Q2    ), 
SDHD_CARHZ  (Q3AFZ5    ), SDHD_CUPPJ  (Q46X58    ), SDHD_FUSNN  (Q8RFX6    ), 
SDHD_HAHCH  (Q2SHX7    ), SDHD_POLNA  (A1VWK8    ), SDHD_RHIE6  (B3PYT5    ), 
SDHD_RHILW  (B5ZNC1    ), SDHD_SINMW  (A6UB95    ), SRR_SCHPO   (O59791    ), 
THD1_CICAR  (Q39469    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

TD_SOLTU    (P31212    )


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			28 sequences
			


			
ACTN3_BOVIN (Q0III9    ), ACTN3_HUMAN (Q08043    ), ACTN3_MOUSE (O88990    ), 

			
ALKD_PSEPU  (P00885    ), AROE_PYRAE  (Q8ZW89    ), BFPB_ECO11  (Q9S142    ), 
BFPB_ECO27  (Q47068    ), CY551_ALLVD (P80549    ), CY551_PSEAE (P00099    ), 
CYSM_CAMJE  (P71128    ), DHOM_HELPJ  (Q9ZL20    ), DHOM_HELPY  (P56429    ), 
DIP2A_MOUSE (Q8BWT5    ), DNLJ_BEII9  (B2IGH4    ), FEOB_LEPIC  (Q72SI0    ), 
FEOB_LEPIN  (Q8F332    ), GCST_PSESM  (Q88AS0    ), HNRLL_HUMAN (Q8WVV9    ), 
HNRLL_MOUSE (Q921F4    ), KAS1_STRVN  (P16540    ), PALLD_HUMAN (Q8WX93    ), 
PLSP2_LOTGI (B3A0P3    ), RL15_AGRFC  (Q8UE36    ), RS20_CUPMC  (Q1LJ99    ), 
RS20_CUPPJ  (Q46XK7    ), RSMG_CLOB8  (A6M3M3    ), SYLC_DICDI  (Q54N83    ), 
YDHG_SCHPO  (Q92361    )


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			34 PDB
			


			1E5X; 1KL7; 1P5J; 1PWE; 1PWH; 1TDJ; 1VB3; 2C2B; 2C2G; 2D1F; 2GN0; 2GN1; 
			
				2GN2; 2RKB; 3HMK; 3IAU; 3L6B; 3L6C; 3L6R; 3R0X; 3R0Z; 3SS7; 3SS9; 4H27; 
				5X2L; 6AA9; 6SLH; 6ZSP; 6ZUJ; 7NBC; 7NBD; 7NBF; 7NBG; 7NBH
			
			

			» more

				
	





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