PROSITE logo

PROSITE entry PS00166


View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] ENOYL_COA_HYDRATASE
Accession [info] PS00166
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
03-MAY-2023 INFO UPDATE.
PROSITE Doc. [info] PDOC00150

Name and characterization of the entry

Description [info] Enoyl-CoA hydratase/isomerase signature.
Pattern [info] 
[LIVM]-[STAG]-x-[LIVM]-[DENQRHSTA]-G-x(3)-[AG](3)-x(4)-[LIVMST]-x-[CSTA]-
[DQHP]-[LIVMFYA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2023_02 which contains 569'516 sequence entries.


Total number of hits 242 in 242 different sequences
Number of true positive hits 220 in 220 different sequences
Number of 'unknown' hits 0
Number of false positive hits 22 in 22 different sequences
Number of false negative sequences 159
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 90.91 %
Recall (true positives / (true positives + false negatives)) 58.05 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 220 sequences 

AIM1_ARATH  (Q9ZPI6    ), AUHM_DICDI  (Q54HG7    ), AUHM_HUMAN  (Q13825    ), 

AUHM_MOUSE  (Q9JLZ3    ), AUHM_RAT    (F1LU71    ), BAMA_GEOMG  (Q39TV7    ), 
BBSH_THAAR  (Q9KJE7    ), CAID_CITK8  (A8ALR7    ), CAID_ECO57  (Q8XA35    ), 
CAID_ECOL5  (Q0TLV3    ), CAID_ECOL6  (Q8FLA6    ), CAID_ECOLC  (B1IRE0    ), 
CAID_ECOLI  (P31551    ), CAID_ECOSM  (B1LFW9    ), CAID_PROMH  (B4EY26    ), 
CAID_PROSL  (Q8GB17    ), CAID_SALA4  (B5F749    ), CAID_SALAR  (A9MR28    ), 
CAID_SALCH  (Q57TJ1    ), CAID_SALDC  (B5FHG4    ), CAID_SALEP  (B5R1Q9    ), 
CAID_SALG2  (B5RGA4    ), CAID_SALHS  (B4TIG9    ), CAID_SALNS  (B4T6J5    ), 
CAID_SALPA  (Q5PIL1    ), CAID_SALPB  (A9MYJ5    ), CAID_SALPC  (C0Q4L2    ), 
CAID_SALPK  (B5BL54    ), CAID_SALSV  (B4TWR3    ), CAID_SALTI  (Q8Z9L5    ), 
CAID_SALTY  (Q8ZRX5    ), CAID_SHIFL  (P59395    ), CBAD1_ARTSP (O85078    ), 
CBAD2_ARTSP (Q9LCU3    ), CBADH_PSEUC (A5JTM5    ), CLAC_PENCR  (A0A481WNM8), 
CRCH_SYNWW  (Q0AVM1    ), CRTL_DICDI  (Q869N6    ), CRT_CLOAB   (P52046    ), 
DCI1_ARATH  (Q9FHR8    ), DMDD_RUEPO  (Q5LLW6    ), DPGD_AMYOR  (G4V4T7    ), 
ECH12_MYCBO (Q7U004    ), ECH12_MYCLE (P53526    ), ECH12_MYCTO (P9WNN6    ), 
ECH12_MYCTU (P9WNN7    ), ECH14_MYCBO (P64019    ), ECH14_MYCTO (P9WNN4    ), 
ECH14_MYCTU (P9WNN5    ), ECH1_DICDI  (Q54SS0    ), ECH1_HUMAN  (Q13011    ), 
ECH1_MOUSE  (O35459    ), ECH1_PONAB  (Q5RFG0    ), ECH1_RAT    (Q62651    ), 
ECH2M_ARATH (F4JML5    ), ECHA6_MYCBO (P64015    ), ECHA6_MYCLE (Q50130    ), 
ECHA6_MYCTO (P9WNP0    ), ECHA6_MYCTU (P9WNP1    ), ECHA8_MYCBO (P64017    ), 
ECHA8_MYCLE (O07137    ), ECHA8_MYCTO (P9WNN8    ), ECHA8_MYCTU (P9WNN9    ), 
ECHA_HUMAN  (P40939    ), ECHA_MOUSE  (Q8BMS1    ), ECHA_PIG    (Q29554    ), 
ECHA_RAT    (Q64428    ), ECHD1_BOVIN (Q2HJD5    ), ECHD1_CHICK (F1NB38    ), 
ECHD1_DANRE (F1R6N4    ), ECHD1_HUMAN (Q9NTX5    ), ECHD1_MOUSE (Q9D9V3    ), 
ECHD1_PONAB (Q5R4W0    ), ECHD1_RAT   (Q6AYG5    ), ECHD1_XENLA (Q5HZQ8    ), 
ECHD1_XENTR (Q28C91    ), ECHD2_BOVIN (Q2TBT3    ), ECHD2_HUMAN (Q86YB7    ), 
ECHD2_MOUSE (Q3TLP5    ), ECHH_RHIME  (Q52995    ), ECHH_RHOCB  (P24162    ), 
ECHM_BOVIN  (Q58DM8    ), ECHM_CAEEL  (P34559    ), ECHM_DICDI  (Q1ZXF1    ), 
ECHM_HUMAN  (P30084    ), ECHM_MOUSE  (Q8BH95    ), ECHM_PONAB  (Q5R646    ), 
ECHM_RAT    (P14604    ), ECHP_CAVPO  (P55100    ), ECHP_DANRE  (Q6NYL3    ), 
ECHP_HUMAN  (Q08426    ), ECHP_MOUSE  (Q9DBM2    ), ECHP_PONAB  (Q5R5M8    ), 
ECHP_RAT    (P07896    ), ECI1_HUMAN  (P42126    ), ECI1_MOUSE  (P42125    ), 
ECI1_RAT    (P23965    ), FADB_ACIAD  (Q6FF68    ), FADB_ACIB3  (B7H1I0    ), 
FADB_ACIB5  (B7I3P1    ), FADB_ACIBC  (B2I2J9    ), FADB_ACIBS  (B0VLX4    ), 
FADB_ACIBY  (B0VE45    ), FADB_ALIF1  (Q5E8X6    ), FADB_ALIFM  (B5FEW8    ), 
FADB_ALISL  (B6EGU2    ), FADB_BACSU  (P94549    ), FADB_CITK8  (A8ACZ4    ), 
FADB_COLP3  (Q489W3    ), FADB_ECO24  (A7ZU51    ), FADB_ECO27  (B7UNH4    ), 
FADB_ECO45  (B7MHD1    ), FADB_ECO55  (B7L9A7    ), FADB_ECO57  (Q8X8I2    ), 
FADB_ECO5E  (B5YY93    ), FADB_ECO7I  (B7NV20    ), FADB_ECO81  (B7N2F2    ), 
FADB_ECO8A  (B7M649    ), FADB_ECOBW  (C5A020    ), FADB_ECODH  (B1XAK8    ), 
FADB_ECOHS  (A8A6V1    ), FADB_ECOL5  (Q0TAL0    ), FADB_ECOL6  (Q8FBI2    ), 
FADB_ECOLC  (B1IW61    ), FADB_ECOLI  (P21177    ), FADB_ECOLU  (B7NFE7    ), 
FADB_ECOSM  (B1LM32    ), FADB_ECOUT  (Q1R466    ), FADB_ENT38  (A4WFX4    ), 
FADB_ENTCL  (Q9F0Y7    ), FADB_ESCF3  (B7LTY9    ), FADB_IDILO  (Q5QXH7    ), 
FADB_KLEP3  (B5XYH0    ), FADB_KLEP7  (A6TGM4    ), FADB_PHOLL  (Q7MZ92    ), 
FADB_PHOPR  (Q6LW06    ), FADB_PSEA7  (A6V382    ), FADB_PSEA8  (B7UYR6    ), 
FADB_PSEAB  (Q02PH8    ), FADB_PSEAE  (Q9HZJ2    ), FADB_PSEE4  (Q1I7D4    ), 
FADB_PSEF5  (Q4KFC4    ), FADB_PSEFR  (P28793    ), FADB_PSEFS  (C3K613    ), 
FADB_PSEOL  (Q93Q12    ), FADB_PSEP1  (A5W6H0    ), FADB_PSEPF  (Q3K9D8    ), 
FADB_PSEPG  (B0KH74    ), FADB_PSEPK  (Q88L02    ), FADB_PSEPU  (Q9AHY3    ), 
FADB_PSEPW  (B1J5A5    ), FADB_SALA4  (B5EZW0    ), FADB_SALCH  (Q57HM6    ), 
FADB_SALEP  (B5QW85    ), FADB_SALG2  (B5RFL6    ), FADB_SALNS  (B4SZ85    ), 
FADB_SALPA  (Q5PKQ2    ), FADB_SALPB  (A9MYB0    ), FADB_SALPK  (B5BIZ0    ), 
FADB_SALSV  (B4TNZ1    ), FADB_SALTI  (Q8Z3C6    ), FADB_SALTY  (Q9L6L5    ), 
FADB_SERP5  (A8G8D1    ), FADB_SHEHH  (B0TLB9    ), FADB_SHEPA  (A8GYG0    ), 
FADB_SHEPW  (B8CH91    ), FADB_SHESH  (A8FP63    ), FADB_SHEWM  (B1KCZ3    ), 
FADB_SHIB3  (B2TVJ5    ), FADB_SHIDS  (Q32A21    ), FADB_SHIF8  (Q0SZ36    ), 
FADB_SHIFL  (Q83PG1    ), FADB_SHISS  (Q3YVC1    ), FADB_VIBA3  (B7VGL4    ), 
FADB_YERE8  (A1JIG4    ), FADB_YERP3  (A7FDF2    ), FADB_YERPA  (Q1C2C4    ), 
FADB_YERPB  (B2K0Z6    ), FADB_YERPE  (Q8ZAN0    ), FADB_YERPG  (A9R754    ), 
FADB_YERPN  (Q1CN99    ), FADB_YERPP  (A4TR27    ), FADB_YERPS  (Q66FR8    ), 
FADB_YERPY  (B1JP63    ), FADJ_ALIF1  (Q5E3U1    ), FADJ_IDILO  (Q5QXM1    ), 
FADJ_PECAS  (Q6D2L7    ), FADJ_PECCP  (C6DAL7    ), FADJ_SHEFN  (Q07ZP8    ), 
FADJ_VIBC1  (A7MS61    ), FADJ_VIBC3  (A5F2P2    ), FADJ_VIBCH  (Q9KT58    ), 
FADJ_VIBPA  (Q87MM3    ), FADJ_VIBVU  (Q8DB47    ), FADJ_VIBVY  (Q7MIS5    ), 
FER4_USTMA  (Q4PEN0    ), HCHL_PSEFL  (O69762    ), HIBCH_YEAST (P28817    ), 
HPCD_METS5  (A4YI89    ), MENB_ARATH  (Q8GYN9    ), MENB_BACSU  (P23966    ), 
MENB_CYACA  (Q9TM10    ), MENB_ECOL6  (P0ABU1    ), MENB_ECOLI  (P0ABU0    ), 
MENB_HAEIN  (P44960    ), MENB_PASMU  (Q9CLV5    ), MENB_SALTY  (Q7CQ56    ), 
MENB_STAEQ  (Q5HQC3    ), MENB_STAES  (Q8CPQ4    ), MENB_STAHJ  (Q4L549    ), 
MENB_STAS1  (Q49WG8    ), MFP2_ARATH  (Q9ZPI5    ), MFPA_BRANA  (O49809    ), 
MFPA_CUCSA  (Q39659    ), MFP_ORYSJ   (Q8W1L6    ), PAAF_ECOLI  (P76082    ), 
PKSH_BACSU  (P40805    ), PKSI_BACSU  (P40802    ), SCPB_ECOLI  (P52045    ), 
YNGF_BACSU  (O34893    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 159 sequences 

CARB_PECCC  (Q9XB60    ), DCH_THAAR   (O87873    ), DPGB_AMYOR  (G4V4T5    ), 

ECH13_MYCTU (P95279    ), ECH17_MYCA1 (A0QJH8    ), ECH17_MYCBO (Q7TXE1    ), 
ECH17_MYCBP (A1KN36    ), ECH17_MYCPA (Q73VC7    ), ECH17_MYCTA (A5U753    ), 
ECH17_MYCTO (P9WNN2    ), ECH17_MYCTU (P9WNN3    ), ECH1P_ARATH (Q6NL24    ), 
ECH20_MYCTU (I6Y3U6    ), ECH20_RHOJR (Q0S7P8    ), ECHD3_DANRE (A0PJR5    ), 
ECHD3_HUMAN (Q96DC8    ), ECHD3_MOUSE (Q9D7J9    ), ECHD3_RAT   (Q3MIE0    ), 
ECHD3_XENLA (A9JS71    ), ECI1_YEAST  (Q05871    ), FABM_STRMU  (Q8DSN0    ), 
FABM_STRR6  (Q8DR19    ), FAD3_RICFE  (Q4UL32    ), FAD3_RICPR  (Q9ZCZ1    ), 
FAD3_RICTY  (Q68WH7    ), FADB_AERHH  (A0KEL1    ), FADB_AERS4  (A4STF2    ), 
FADB_CROS8  (A7MQP0    ), FADB_ECOSE  (B6I4I6    ), FADB_PECAS  (Q6DAP5    ), 
FADB_PSE14  (Q48GW3    ), FADB_PSEMY  (A4XSM8    ), FADB_PSESM  (Q87ZB2    ), 
FADB_PSEU2  (Q4ZRA0    ), FADB_PSYA2  (Q4FQC6    ), FADB_PSYCK  (Q1Q8J9    ), 
FADB_PSYWF  (A5WH99    ), FADB_SHEAM  (A1S1I8    ), FADB_SHEB2  (B8E3R3    ), 
FADB_SHEB5  (A3CYJ4    ), FADB_SHEB8  (A6WHA0    ), FADB_SHEB9  (A9KU91    ), 
FADB_SHEFN  (Q08A39    ), FADB_SHELP  (A3Q8U4    ), FADB_SHEON  (Q8EKR9    ), 
FADB_SHEPC  (A4Y1B6    ), FADB_SHESA  (A0KR50    ), FADB_SHESM  (Q0HPB7    ), 
FADB_SHESR  (Q0I0T3    ), FADB_SHESW  (A1RDW6    ), FADB_STUS1  (A4VKA3    ), 
FADB_VIBC1  (A7N1D2    ), FADB_VIBC3  (A5F465    ), FADB_VIBCH  (Q9KNI1    ), 
FADB_VIBCM  (C3LSI3    ), FADB_VIBPA  (Q87TN9    ), FADB_VIBVU  (Q8DDK6    ), 
FADB_VIBVY  (Q7MQH9    ), FADJ_CITK8  (A8ADP2    ), FADJ_CROS8  (A7MH81    ), 
FADJ_ECO24  (A7ZPF8    ), FADJ_ECO27  (B7UFZ8    ), FADJ_ECO45  (B7MGV7    ), 
FADJ_ECO55  (B7LBJ5    ), FADJ_ECO57  (Q8XCP2    ), FADJ_ECO5E  (B5YXY4    ), 
FADJ_ECO7I  (B7NP24    ), FADJ_ECO81  (B7MY16    ), FADJ_ECO8A  (B7M6M2    ), 
FADJ_ECOBW  (C4ZVN2    ), FADJ_ECODH  (B1X9L4    ), FADJ_ECOHS  (A8A2L0    ), 
FADJ_ECOK1  (A1ADI8    ), FADJ_ECOL5  (Q0TFA6    ), FADJ_ECOL6  (Q8FFG4    ), 
FADJ_ECOLC  (B1IXA5    ), FADJ_ECOLI  (P77399    ), FADJ_ECOLU  (B7N5V2    ), 
FADJ_ECOSE  (B6I6Q4    ), FADJ_ECOSM  (B1LME7    ), FADJ_ECOUT  (Q1R972    ), 
FADJ_ENT38  (A4WCW6    ), FADJ_ESCF3  (B7LLD0    ), FADJ_KLEP3  (B5XVW2    ), 
FADJ_KLEP7  (A6TC19    ), FADJ_PHOLL  (Q7N288    ), FADJ_PHOPR  (Q6LTK3    ), 
FADJ_SALA4  (B5EZR9    ), FADJ_SALCH  (Q57LW6    ), FADJ_SALDC  (B5FPN1    ), 
FADJ_SALEP  (B5R3R9    ), FADJ_SALG2  (B5RCL3    ), FADJ_SALHS  (B4TCA8    ), 
FADJ_SALNS  (B4SZR0    ), FADJ_SALPA  (Q5PCX6    ), FADJ_SALPB  (A9N453    ), 
FADJ_SALPK  (B5BBA1    ), FADJ_SALSV  (B4TQC2    ), FADJ_SALTI  (Q8Z4Z0    ), 
FADJ_SALTY  (Q8ZNA7    ), FADJ_SERP5  (A8GH86    ), FADJ_SHEAM  (A1S7L6    ), 
FADJ_SHEB5  (A3D684    ), FADJ_SHEB8  (A6WQ25    ), FADJ_SHEHH  (B0TL21    ), 
FADJ_SHELP  (A3QFP3    ), FADJ_SHEON  (Q8ECP7    ), FADJ_SHEPC  (A4Y897    ), 
FADJ_SHESA  (A0KV76    ), FADJ_SHESM  (Q0HKD1    ), FADJ_SHESR  (Q0HWN3    ), 
FADJ_SHESW  (A1RI92    ), FADJ_SHIB3  (B2TWV4    ), FADJ_SHIBS  (Q31YB7    ), 
FADJ_SHIDS  (Q32DJ4    ), FADJ_SHIF8  (Q0T2E6    ), FADJ_SHIFL  (Q83QQ0    ), 
FADJ_SHISS  (Q3YZM2    ), FADJ_YERE8  (A1JK30    ), FADJ_YERP3  (A7FGK1    ), 
FADJ_YERPA  (Q1C660    ), FADJ_YERPE  (Q8ZD45    ), FADJ_YERPN  (Q1CHK2    ), 
FADJ_YERPP  (A4TM82    ), FADJ_YERPS  (Q668V1    ), HIBC1_ARATH (Q9LKJ1    ), 
HIBC2_ARATH (Q1PEY5    ), HIBC3_ARATH (Q6NMB0    ), HIBC4_ARATH (Q5XF59    ), 
HIBC5_ARATH (Q8RXN4    ), HIBC6_ARATH (Q9T0K7    ), HIBC7_ARATH (Q9LK08    ), 
HIBC8_ARATH (Q9SHJ8    ), HIBCH_BOVIN (Q2HJ73    ), HIBCH_CHICK (Q5ZJ60    ), 
HIBCH_DANRE (Q58EB4    ), HIBCH_DICDI (Q55GS6    ), HIBCH_HUMAN (Q6NVY1    ), 
HIBCH_MOUSE (Q8QZS1    ), HIBCH_RAT   (Q5XIE6    ), HIBCH_SCHPO (O74802    ), 
HIBCH_XENLA (A2VDC2    ), HIBCH_XENTR (Q28FR6    ), HTDX_MYCTU  (O53664    ), 
HTDY_MYCTU  (I6YBZ8    ), HTDZ_MYCBO  (Q7U2S5    ), HTDZ_MYCTO  (P9WNP2    ), 
HTDZ_MYCTU  (P9WNP3    ), MENB_MYCS2  (A0QRD3    ), MENB_MYCTO  (P9WNP4    ), 
MENB_MYCTU  (P9WNP5    ), MENB_STAAC  (Q5HH38    ), MENB_STAAM  (Q99V48    ), 
MENB_STAAN  (Q7A6A9    ), MENB_STAAR  (Q6GI37    ), MENB_STAAS  (Q6GAG7    ), 
MENB_STAAW  (Q8NXA0    ), PAAG_ECOLI  (P77467    ), YHAR_BACSU  (O07533    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

CRT_CLODI   (P45361    ), CRT_CLOPA   (P81357    )


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			22 sequences
			


			
LKA11_MANHA (P55118    ), LKA13_MANHA (Q9EV31    ), LKA14_MANHA (Q9EV33    ), 

			
LKA16_MANHA (Q9EV32    ), LKA1A_MANHA (P16535    ), LKA1B_MANHA (Q7BHI8    ), 
LKA2A_MANHA (Q9EV30    ), LKA2B_MANHA (P0C081    ), LKA2C_MANHA (P0C082    ), 
LKA2D_MANHA (Q9EV29    ), LKA2E_MANHA (Q9EV27    ), LKA7A_MANHA (P0C084    ), 
LKA7B_MANHA (P0C085    ), LKTA6_MANHA (P0C083    ), LKTA8_MANHA (Q9EV34    ), 
LKTA_BIBTR  (P55117    ), LKTA_MANGL  (Q9ETX2    ), LKTA_PASSP  (P55123    ), 
NRT23_ORYSJ (Q94JG1    ), NRT25_ARATH (Q9LPV5    ), RFIP5_HUMAN (Q9BXF6    ), 
SYE1_ROSDO  (Q16AX5    )


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			82 PDB
			


			1DCI; 1DUB; 1EF8; 1EF9; 1EY3; 1HZD; 1JXZ; 1MJ3; 1NZY; 1SG4; 1WDK; 1WDL; 
			
				1WDM; 1XX4; 2D3T; 2DUB; 2HW5; 2J5I; 2VRE; 2VSS; 2VSU; 2WTB; 2X58; 2ZQQ; 
				2ZQR; 3H02; 3H81; 3HE2; 3HP0; 3PZK; 3Q0G; 3Q0J; 3T88; 3T89; 3ZW8; 3ZW9; 
				3ZWA; 3ZWB; 3ZWC; 4ELS; 4ELW; 4ELX; 4FJW; 4FZW; 4I42; 4IZB; 4IZC; 4IZD; 
				4Q1G; 4Q1H; 4Q1I; 4Q1J; 4Q1K; 5DTP; 5DTW; 5DU4; 5DU6; 5DU8; 5DUC; 5DUF; 
				5MGB; 5MRC; 5MRE; 5MRF; 5OMO; 5Z7R; 5ZAI; 5ZQZ; 5ZRV; 6DV2; 6N92; 6N93; 
				6N94; 6N95; 6N96; 6N97; 6TNM; 6Z5F; 6Z5O; 6Z5V; 6ZIB; 6ZIC
			
			

			» more