PROSITE logo

PROSITE entry PS00170


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] CSA_PPIASE_1
Accession [info] PS00170
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00154

Name and characterization of the entry

Description [info] Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature.
Pattern [info]
[FY]-x(2)-[STCNLVA]-x-[FV]-H-[RH]-[LIVMNS]-[LIVM]-x(2)-F-[LIVM]-x-Q-
[AGFT]-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 256 in 256 different sequences
Number of true positive hits 256 in 256 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 61
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 80.76 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
256 sequences

CP18A_ARATH (Q9LPC7), CP18B_ARATH (Q9SIH1), CP18C_ARATH (P34790), 
CP18D_ARATH (Q42406), CP19A_ARATH (Q38900), CP19B_ARATH (Q9SKQ0), 
CP19C_ARATH (Q38867), CP19D_ARATH (Q8LDP4), CP20A_ARATH (Q9SP02), 
CP20C_ARATH (P34791), CP21A_ARATH (O49605), CP21B_ARATH (Q8L8W5), 
CPY57_ARATH (Q6Q152), CWC27_ASPFU (Q4WE62), CWC27_BOVIN (Q17QX9), 
CWC27_DANRE (Q7ZW86), CWC27_EMENI (Q5AUG9), CWC27_GIBZE (Q4IPB3), 
CWC27_HUMAN (Q6UX04), CWC27_MACFA (Q4R713), CWC27_MOUSE (Q3TKY6), 
CWC27_NEUCR (Q7SBX8), CWC27_PONAB (Q5R7W3), CWC27_RAT   (Q5XIB2), 
CWC27_RHIO9 (P0C1J2), CWC27_USTMA (Q4P7H2), CWC27_XENLA (Q6GLX7), 
CYP10_CAEEL (P52017), CYP11_CAEEL (P52018), CYP11_RHIO9 (P0C1I9), 
CYP15_RHIO9 (P0C1J0), CYP1_BRUMA  (Q27450), CYP1_CAEEL  (P52009), 
CYP1_SOYBN  (Q8W171), CYP2_CAEEL  (P52010), CYP3_CAEEL  (P52011), 
CYP40_ARATH (Q9C566), CYP5_CAEEL  (P52013), CYP5_RHIO9  (P0C1I7), 
CYP63_ARATH (Q9LY75), CYP6_CAEEL  (P52014), CYP6_RHIO9  (P0C1I8), 
CYP7_CAEEL  (P52015), CYP7_SCHPO  (O42941), CYP7_YEAST  (P47103), 
CYP8_CAEEL  (P52016), CYP9_CAEEL  (Q09637), CYP9_SCHPO  (O74942), 
CYPB_ARTBC  (D4AY02), CYPB_VICFA  (Q41651), CYPB_YEAST  (P23285), 
CYPC_YEAST  (P25719), CYPD_YEAST  (P35176), CYPE_DICDI  (Q9NI62), 
CYPH_ALLCE  (P34887), CYPH_BRANA  (P24525), CYPH_CATRO  (Q39613), 
CYPH_ENCCU  (Q8SRE1), CYPH_LUPLU  (O49886), CYPH_MAIZE  (P21569), 
CYPH_NEUCR  (P10255), CYPH_SCHPO  (P18253), CYPH_SOLLC  (P21568), 
CYPH_UROFA  (O00060), CYPH_YEAST  (P14832), CYPR_CALVI  (P28517), 
CYPR_DROME  (P15425), CYPX_USEUD  (P35627), NKTR_HUMAN  (P30414), 
NKTR_MOUSE  (P30415), PAL4A_HUMAN (Q9Y536), PAL4C_HUMAN (A0A0B4J2A2), 
PAL4D_HUMAN (F5H284), PAL4E_HUMAN (A0A075B759), PAL4F_HUMAN (P0DN26), 
PAL4G_HUMAN (P0DN37), PAL4H_HUMAN (A0A075B767), PNSL5_ARATH (Q9ASS6), 
PPI1_BRUA2  (Q2YPY5), PPI1_BRUAB  (Q57D43), PPI1_BRUME  (Q8YHB5), 
PPI1_BRUSU  (Q8G0J9), PPI1_STAEQ  (Q5HQK8), PPI1_STAES  (Q8CT84), 
PPI1_STAS1  (Q49W93), PPI1_SYNY3  (P72704), PPI2_SYNY3  (P73789), 
PPIA1_RHIO9 (P0C1H7), PPIA2_RHIO9 (P0C1H8), PPIA_ACIAD  (P42693), 
PPIA_AOTTR  (Q6DTV9), PPIA_BLAGE  (P54985), PPIA_BOVIN  (P62935), 
PPIA_CANAL  (P22011), PPIA_CHLAE  (P62938), PPIA_CRIGR  (P14851), 
PPIA_DICD3  (O53021), PPIA_DICDI  (Q54SM3), PPIA_DROME  (P25007), 
PPIA_ECHGR  (P14088), PPIA_ECO57  (P0AFL5), PPIA_ECOL6  (P0AFL4), 
PPIA_ECOLI  (P0AFL3), PPIA_FELCA  (Q8HXS3), PPIA_GORGO  (Q0ZQL0), 
PPIA_HELPJ  (Q9ZJH5), PPIA_HELPY  (O25982), PPIA_HEMPU  (P91791), 
PPIA_HUMAN  (P62937), PPIA_HYLLA  (Q0ZQK8), PPIA_MACMU  (P62940), 
PPIA_MOUSE  (P17742), PPIA_MYCBO  (P65763), PPIA_MYCLE  (Q9CDE9), 
PPIA_MYCTO  (P9WHW2), PPIA_MYCTU  (P9WHW3), PPIA_NEOCA  (P84343), 
PPIA_NOMLE  (Q0ZQK7), PPIA_PANPA  (Q0ZQL2), PPIA_PANTR  (Q0ZQL1), 
PPIA_PAPAN  (P62941), PPIA_PARPR  (O00845), PPIA_PIG(P62936), 
PPIA_PONPY  (Q5R8S7), PPIA_PSEAE  (Q59641), PPIA_RABIT  (Q9TTC6), 
PPIA_RAT(P10111), PPIA_SAGOE  (Q0ZQK3), PPIA_SALTY  (P20753), 
PPIA_SCHMA  (Q26565), PPIA_STRAQ  (Q06118), PPIA_SYMSY  (Q0ZQK6), 
PPIB1_RHIO9 (P0C1H9), PPIB2_RHIO9 (P0C1I0), PPIB_ARTBE  (O93826), 
PPIB_ASPFU  (Q4WP12), PPIB_ASPNG  (Q8X166), PPIB_ASPOR  (Q2UGK2), 
PPIB_BACSU  (P35137), PPIB_BOVIN  (P80311), PPIB_CHICK  (P24367), 
PPIB_CRYNB  (P0CP79), PPIB_CRYNJ  (P0CP78), PPIB_DICDI  (Q9TW32), 
PPIB_ECOLI  (P23869), PPIB_EMENI  (Q5B4R3), PPIB_GIBZE  (Q4I5R9), 
PPIB_HAEIN  (P44499), PPIB_HUMAN  (P23284), PPIB_MOUSE  (P24369), 
PPIB_NEUCR  (Q7S7Z6), PPIB_ORPSP  (Q01490), PPIB_RAT(P24368), 
PPIB_SCHJA  (Q27774), PPIB_SCHMA  (Q26551), PPIB_SCHPO  (O94273), 
PPIB_STRAQ  (P77949), PPIB_STRAT  (P83221), PPIB_TREPA  (O66105), 
PPIB_YARLI  (Q6C4W6), PPIC_BOVIN  (Q08E11), PPIC_HUMAN  (P45877), 
PPIC_MOUSE  (P30412), PPID_AMAMU  (Q5U8Z7), PPID_ASPFU  (Q4WIF3), 
PPID_ASPOR  (Q2U0E0), PPID_BOVIN  (P26882), PPID_CANAL  (Q5ACI8), 
PPID_CANGA  (Q6FNU6), PPID_DEBHA  (Q6BXZ7), PPID_DICDI  (Q9UA41), 
PPID_EMENI  (Q5B4E7), PPID_EREGS  (Q75A33), PPID_GIBZE  (Q4HXF6), 
PPID_HUMAN  (Q08752), PPID_KLULA  (Q6CL78), PPID_MOUSE  (Q9CR16), 
PPID_NEUCR  (Q9P3X9), PPID_RAT(Q6DGG0), PPID_RHIO9  (P0C1I1), 
PPID_SCHPO  (Q11004), PPID_USTMA  (Q4P0V4), PPID_YARLI  (Q6CBP4), 
PPID_YEAST  (P53691), PPIE_BOVIN  (A4FV72), PPIE_DROME  (Q9V3G3), 
PPIE_HAECO  (Q4G338), PPIE_HUMAN  (Q9UNP9), PPIE_MOUSE  (Q9QZH3), 
PPIE_PONAB  (Q5R723), PPIE_RHIO9  (P0C1I2), PPIE_SCHJA  (Q26516), 
PPIE_SCHMA  (Q26548), PPIF_BOVIN  (P30404), PPIF_HUMAN  (P30405), 
PPIF_MOUSE  (Q99KR7), PPIF_RAT(P29117), PPIG_HUMAN  (Q13427), 
PPIG_MOUSE  (A2AR02), PPIG_RAT(O55035), PPIH_ASPFU  (Q4WCM6), 
PPIH_ASPOR  (Q2TZ33), PPIH_BOVIN  (Q0P5D0), PPIH_CRYNB  (P0CP83), 
PPIH_CRYNJ  (P0CP82), PPIH_EMENI  (Q5AQL0), PPIH_GIBZE  (Q4IPH4), 
PPIH_HUMAN  (O43447), PPIH_MOUSE  (Q9D868), PPIH_NEUCR  (Q7SG06), 
PPIH_RHIO9  (P0C1I3), PPIH_SCHPO  (O74729), PPIH_USTMA  (Q4P6X6), 
PPIL1_ASPFU (Q4WCR3), PPIL1_ASPNG (Q8X191), PPIL1_ASPOR (Q2U6U0), 
PPIL1_BOVIN (Q5E992), PPIL1_CRYNB (P0CP85), PPIL1_CRYNJ (P0CP84), 
PPIL1_EMENI (Q5ASQ0), PPIL1_GIBZE (Q4I1Y1), PPIL1_HUMAN (Q9Y3C6), 
PPIL1_MOUSE (Q9D0W5), PPIL1_NEUCR (Q7SF72), PPIL1_RHIO9 (P0C1I4), 
PPIL1_SCHPO (P87051), PPIL2_ARATH (Q9FJX0), PPIL2_ASPFU (Q4WVU5), 
PPIL2_ASPOR (Q2U5W8), PPIL2_CAEEL (P52012), PPIL2_CRYNB (P0CP91), 
PPIL2_CRYNJ (P0CP90), PPIL2_EMENI (Q5AXT6), PPIL2_GIBZE (Q4IBK5), 
PPIL2_HUMAN (Q13356), PPIL2_MOUSE (Q9D787), PPIL2_NEUCR (Q7RXA6), 
PPIL2_RHIO9 (P0C1J1), PPIL2_SCHPO (Q09928), PPIL2_USTMA (Q4P555), 
PPIL3_CHICK (Q5ZLV2), PPIL3_CRYNB (P0CP87), PPIL3_CRYNJ (P0CP86), 
PPIL3_DICDI (Q54E95), PPIL3_EMENI (Q5BAH7), PPIL3_GIBZE (Q4IPB8), 
PPIL3_HUMAN (Q9H2H8), PPIL3_MOUSE (Q9D6L8), PPIL3_NEUCR (Q6MWS8), 
PPIL3_RAT   (Q812D3), PPI_LOTGI   (B3A0R0), PPI_SYNE7   (P29820), 
RBP2_BOVIN  (P48820), RBP2_HUMAN  (P49792), RBP2_MOUSE  (Q9ERU9), 
RBP2_PANTR  (H2QII6)
» more

UniProtKB/Swiss-Prot
False negative sequences
61 sequences

BPPI_STRP6  (Q5XAQ1), CP21C_ARATH (Q94A16), CP21D_ARATH (Q9C835), 
CP26A_ARATH (Q9LIK6), CP26B_ARATH (F4HTT6), CPY28_ARATH (O65220), 
CPY71_ARATH (Q8W4D0), CWC27_CRYNB (P0CP93), CWC27_CRYNJ (P0CP92), 
CWC27_DEBHA (Q6BWH6), CWC27_EREGS (Q75A74), CWC27_YARLI (Q6CGK4), 
CWC27_YEAST (Q02770), CYP22_ARATH (Q9ZVJ4), CYP23_ARATH (Q8LDR3), 
CYP37_ARATH (P82869), CYP38_ARATH (Q9SSA5), CYP59_ARATH (Q6Q151), 
CYP8_YEAST  (P53728), CYP95_ARATH (Q8RWY7), CYP9_CAEBR  (A8X8D0), 
CYPR_YEAST  (P25334), PPI1_STAA3  (Q2FIC1), PPI1_STAA8  (Q2FZU9), 
PPI1_STAAB  (Q2YWT2), PPI1_STAAC  (Q5HHD1), PPI1_STAAM  (Q99VD4), 
PPI1_STAAN  (Q7A6I1), PPI1_STAAR  (Q6GID4), PPI1_STAAS  (Q6GAX2), 
PPI1_STAAW  (Q7A1C0), PPI1_STAHJ  (Q4L4W9), PPI3_SYNY3  (Q55118), 
PPIB_MYCLE  (P46697), PPIB_MYCTO  (P9WHW0), PPIB_MYCTU  (P9WHW1), 
PPID_CRYNB  (P0CP81), PPID_CRYNJ  (P0CP80), PPIL3_RHIO9 (P0C1I5), 
PPIL3_USTMA (Q4PCH8), PPIL4_ASPFU (Q4WAQ9), PPIL4_ASPOR (Q2U256), 
PPIL4_CRYNB (P0CP89), PPIL4_CRYNJ (P0CP88), PPIL4_EMENI (Q5ARI5), 
PPIL4_GIBZE (Q4IE79), PPIL4_HUMAN (Q8WUA2), PPIL4_MOUSE (Q9CXG3), 
PPIL4_NEUCR (Q871A4), PPIL4_RHIO9 (P0C1I6), PPIL4_SCHPO (Q9UUE4), 
PPIL4_USTMA (P0C196), PPIL6_BOVIN (Q1RMP7), PPIL6_HUMAN (Q8IXY8), 
PPIL6_MOUSE (Q9D6D8), PPWD1_BOVIN (Q29RZ2), PPWD1_HUMAN (Q96BP3), 
PPWD1_MOUSE (Q8CEC6), PPWD1_PONAB (Q5NVL7), SIG7_CAEEL  (G5EEW6), 
TLP40_SPIOL (O49939)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
5 sequences

CYPH_BETPN  (P81531), PPIA_NAEFO  (P84342), PPIA_PENGL  (P85444), 
PPIM_MAIZE  (Q10724), TLP20_SPIOL (P82536)
» more

PDB
[Detailed view]
351 PDB

1A33; 1A58; 1AK4; 1AWQ; 1AWR; 1AWS; 1AWT; 1AWU; 1AWV; 1BCK; 1C5F; 1CLH; 1CWA; 1CWB; 1CWC; 1CWF; 1CWH; 1CWI; 1CWJ; 1CWK; 1CWL; 1CWM; 1CWO; 1CYN; 1DYW; 1E3B; 1E8K; 1FGL; 1H0P; 1IHG; 1IIP; 1IST; 1J2A; 1LOP; 1M63; 1M9C; 1M9D; 1M9E; 1M9F; 1M9X; 1M9Y; 1MF8; 1MIK; 1MZW; 1NMK; 1OCA; 1QOI; 1RMH; 1V9T; 1VAI; 1VBS; 1VBT; 1VDN; 1W74; 1W8L; 1W8M; 1W8V; 1XWN; 1XYH; 1YND; 1ZKC; 1ZKF; 1ZMF; 2ALF; 2BIT; 2BIU; 2CK1; 2CMT; 2CPL; 2CYH; 2ESL; 2GW2; 2HE9; 2HQ6; 2IGV; 2IGW; 2K7N; 2MC9; 2MS4; 2MZU; 2N0T; 2NUL; 2OJU; 2OK3; 2R99; 2RMA; 2RMB; 2RMC; 2RS4; 2WFI; 2WFJ; 2WLW; 2X25; 2X2A; 2X2C; 2X2D; 2X7K; 2XGY; 2Z6W; 3CYH; 3CYS; 3ICH; 3ICI; 3JB9; 3K0M; 3K0N; 3K0O; 3K0P; 3K0Q; 3K2C; 3ODI; 3ODL; 3QYU; 3R49; 3R4G; 3R54; 3R56; 3R57; 3R59; 3RCF; 3RCG; 3RCI; 3RCK; 3RCL; 3RD9; 3RDA; 3RDB; 3RDC; 3RDD; 3UCH; 4CYH; 4DGA; 4DGB; 4DGC; 4DGD; 4DGE; 4I9Y; 4IPZ; 4J58; 4J59; 4J5A; 4J5B; 4J5C; 4J5D; 4J5E; 4LQW; 4N1M; 4N1N; 4N1O; 4N1P; 4N1Q; 4N1R; 4N1S; 4O8H; 4O8I; 4R3E; 4TOT; 4XNC; 4YUG; 4YUH; 4YUI; 4YUJ; 4YUK; 4YUL; 4YUM; 4YUN; 4YUO; 4YUP; 4ZSC; 4ZSD; 5A0E; 5CBT; 5CBU; 5CBV; 5CBW; 5CCN; 5CCQ; 5CCR; 5CCS; 5CYH; 5F66; 5FJB; 5HSV; 5JHE; 5KUL; 5KUN; 5KUO; 5KUQ; 5KUR; 5KUS; 5KUU; 5KUV; 5KUW; 5KUZ; 5KV0; 5KV1; 5KV2; 5KV3; 5KV4; 5KV5; 5KV6; 5KV7; 5LUD; 5MQF; 5NOQ; 5NOR; 5NOS; 5NOT; 5NOU; 5NOV; 5NOW; 5NOX; 5NOY; 5NOZ; 5O9Z; 5T9U; 5T9W; 5T9Z; 5TA2; 5TA4; 5WC7; 5XJC; 5YZG; 5Z56; 5Z57; 5Z58; 6AHD; 6BTA; 6FF4; 6FF7; 6FK1; 6GJI; 6GJJ; 6GJL; 6GJM; 6GJN; 6GJP; 6GJR; 6GJY; 6GS6; 6I42; 6ICZ; 6ID0; 6ID1; 6QDV; 6R8L; 6R8O; 6R8W; 6R9S; 6R9U; 6R9X; 6RA1; 6U5C; 6U5D; 6U5E; 6U5G; 6X3R; 6X3Y; 6X4M; 6X4N; 6X4O; 6X4P; 6X4Q; 6Y3E; 6Y9V; 6Y9W; 6Y9X; 6Y9Y; 6Y9Z; 6YBM; 6ZDJ; 6ZYM; 7A5P; 7ABI; 7ABT; 7DVQ; 7N3J; 7N9X; 7OGI; 7PCJ; 7PMT; 7Q6P; 7QBW; 7QTT; 7R2H; 7R2I; 7R2J; 7R2L; 7R5J; 7R5K; 7RFD; 7TA8; 7TGS; 7TGT; 7TGU; 7TGV; 7TH1; 7TH6; 7TH7; 7THC; 7THD; 7THF; 7UPN; 7UXJ; 7UXM; 7UXN; 7W59; 7W5A; 7W5B; 7WFF; 7WG5; 7ZDN; 8C6J; 8CH6; 8EJX; 8G9P; 8G9Q; 8H6K; 8H6L; 8HZ8; 8I0P; 8I0R; 8I0S; 8I0T; 8I0U; 8I0V; 8I0W; 8QO9; 8QZS; 8R09; 8R0B; 8RM5; 8TBF; 8TBG; 8TBH; 8TBI; 8TBJ; 8TBK; 8TBL; 8TBM; 8TBN; 8UC4; 8UC5; 8VRG; 8VRH; 8VRI; 8XCK; 9AX6; 9BFY; 9BG1; 9FMD
» more